anti-Synuclein, beta (SNCB) Antikörper

The protein encoded by SNCB is highly homologous to alpha-synuclein. Zusätzlich bieten wir Ihnen beta Synuclein Proteine (18) und beta Synuclein Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SNCB 6620 Q16143
SNCB 104069 Q91ZZ3
SNCB 113893 Q63754
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Top anti-beta Synuclein Antikörper auf antikoerper-online.de

Showing 10 out of 99 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of Beta-synuclein staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of Beta-synuclein expression in HeLa (A), human brain (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6268871 at 1/100 staining Human brain cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of Synuclein β expression in HeLa cell lysate.The lane on the left is treated with the antigen-specific peptide. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
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Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa cells, using Synuclein beta Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Synuclein beta Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
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Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen Verfügbar
$181.73
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Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB Anti-SNCB / Beta-Synuclein antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104401 concentration 10 ug/ml. 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB SNCB Antibody (C-term) (ABIN652024) western blot analysis in mouse cerebellum tissue lysates (15 µg/lane). This demonstrates the SNCB antibody detected SNCB protein (arrow). SNCB antibody(C-term) (ABIN652024) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
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Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: beta-Synuclein Antibody  - Staining in human cerebral cortex and liver tissues using anti-SNCB antibody. Corresponding SNCB RNA-seq data are presented for the same tissues. Immunohistochemistry-Paraffin: beta-Synuclein Antibody  - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells, cells in the molecular layer and cells in the granular layer. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
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Human Kaninchen Unkonjugiert IF, IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$434.50
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$478.50
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Human Kaninchen Unkonjugiert ELISA, IF, IHC (p), WB 200 μL Anmelden zum Anzeigen 12 bis 14 Tage
$438.90
Details

Am meisten referenzierte anti-beta Synuclein Antikörper

  1. Human Polyclonal beta Synuclein Primary Antibody für WB - ABIN541122 : Bruening, Giasson, Klein-Szanto, Lee, Trojanowski, Godwin: Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. in Cancer 2000 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen beta Synuclein Interaktionspartner

Human Synuclein, beta (SNCB) Interaktionspartner

  1. These studies could be helpful in understanding collective human synuclein behavior in various protein environments and in the modulation of the homeostasis between beta-syn and healthy versus corrupt alpha- and gamma-syn that can potentially affect PD pathology.

  2. Cells that overexpress alpha-syn showed increased susceptibility to the toxicity of the oligomers, while those that overexpressed beta-syn showed increased resistance to the toxic oligomers.

  3. alterations in the plasma alpha-synuclein and beta-synuclein levels might be implicated in the association between synaptic abnormalities and autism spectrum disorder pathogenesis.

  4. Study suggests that beta-synuclein changes in Dementia with Lewy bodies may exacerbate neuronal dysfunction caused by accumulation of alpha-synuclein by influencing protein degradation.

  5. Data suggest that pH serves as an on/off switch for beta- synuclein to form aggregates/fibrils (as seem in Parkinson disease); hydrogen bonding between glutamate residues appears to be involved in fibril formation.

  6. Cellular pathways affected by bSyn are similar to those affected by aSyn, including impairment of vesicular trafficking and induction of oxidative stress.

  7. loss of inhibitory C-terminal conformations in disease associated P123H beta-synuclein

  8. beta-Synuclein expression was locally concentrated and rather modest, but nevertheless changed its effect on amyloid precursor protein expression and plaque load in a time- and concentration-dependent manner.

  9. The differing aggregation propensities of alpha-synuclein and beta-synuclein are associated with differences in the degree of residual structure in the C-terminus coupled to the shorter separation between the N- and C-termini in beta-synuclein.

  10. Beta-synuclein protects against isoaspartate accumulation in alpha-synuclein.

  11. both alphaS- and P123H betaS-globules were formed through similar but distinct pathogenic mechanisms.

  12. In vivo cross-linking reveals principally oligomeric forms of alpha-synuclein and beta-synuclein in neurons and non-neural cells

  13. Thermodynamic studies in conjunction with EPR confirm that alpha-synuclein, beta-synuclein, and gamma-synuclein bind copper(II) in a high affinity 1:1 stoichiometry.

  14. Data provide evidence for the role of beta-synuclein minor transcript variants in the development of complex diseases and provide new insights into the pathogenesis of Lewy body diseases.

  15. This study suggested that the pathogenesis of dementia in Parkinson disease, indicating that differential sncb expression in the caudate nucleus may represent one of the molecular mechanisms involved in these complex diseases.

  16. Despite both synucleins sharing considerable sequence homology, the level of carboxy-terminal Src kinase-homologous kinase (CHK) phosphorylation of beta-synuclein is significantly higher than that of alpha-synuclein.

  17. Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1.

  18. Synuclein-alpha, -beta, and -gamma are important in regulating neurotransmitter release from specific populations of midbrain dopamine neurons through mechanisms that differ from those reported in other neurons.

  19. Studies identified molecular interaction domains within the beta-synuclein polypeptide that specifically binds alpha-synuclein.

  20. beta-Synuclein mRNA expression in the control group was significantly higher than that in the schizophrenic group.

Mouse (Murine) Synuclein, beta (SNCB) Interaktionspartner

  1. the expression patterns of neuronal maturation markers in the brain of a mouse model of dementia with Lewy body-linked mutant beta-synuclein (betaS), especially in the hippocampus.

  2. These results suggest that synucleins are important orchestrators of presynaptic terminal topography.

  3. Immunoblot analysis of beta-synuclein and Akt levels in the mice reveals selective increases in beta-synuclein and phosphorylated Akt levels in ventral midbrain

  4. Synuclein-alpha, -beta, and -gamma are important in regulating neurotransmitter release from specific populations of midbrain dopamine neurons through mechanisms that differ from those reported in other neurons.

  5. late onset phenotypes in synuclein null mice were not due to a loss of synapses or neurons but rather reflect specific changes in synaptic protein composition and axonal structure

  6. Beta-synuclein decreased formation of Lewy bodies by 40%, and prevented functional deficits associated with overexpression of alpha-synuclein. This is a preliminary in vivo proof of antiaggregatory function of beta-synuclein.

  7. Accelerated accumulation of beta-synuclein is found in axonal spheroids of gracile axonal dystrophy mice, which do not express ubiquitin carboxyl-terminal hydrolase L1.

  8. beta-synuclein knockout mice show that synucleins are not essential components of the basic machinery for neurotransmitter release but may contribute to the long-term regulation and/or maintenance of presynaptic function.

  9. Developmentally, gamma-synuclein can be seen in the region of the outer hair cells by E19, while alpha- and beta-synuclein do not clearly appear there until approximately P10

Zebrafish Synuclein, beta (SNCB) Interaktionspartner

  1. Pla2g6 deficiency resulted in axonal degeneration, dopaminergic and motor neuron cell loss, and increased beta-synuclein expression.

  2. Hypokinesia and reduced dopamine levels in zebrafish lacking beta- and gamma1-synucleins.

  3. Data show the sequences of zebrafish synucleins are very similar to those of the human proteins. Whole-mount in situ hybridization show that sncb were expressed strongly in the nervous system.

beta Synuclein (SNCB) Antigen-Profil

Protein Überblick

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease\; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Synuclein, beta (SNCB) Antikörper

  • synuclein beta (SNCB) Antikörper
  • synuclein, beta (Sncb) Antikörper
  • synuclein, beta (sncb) Antikörper
  • synuclein beta (sncb) Antikörper
  • synuclein beta L homeolog (sncb.L) Antikörper
  • Beta-synuclein (syub) Antikörper
  • AI838531 Antikörper
  • betaSYN Antikörper
  • LOC619281 Antikörper
  • MGC75784 Antikörper
  • SNCB Antikörper
  • syub Antikörper
  • zgc:66343 Antikörper

Bezeichner auf Proteinebene für anti-Synuclein, beta (SNCB) Antikörper

beta-synuclein , PNP 14 , phosphoneuroprotein 14 , zSyn-&beta , zSynC , synuclein, beta , putative beta-synuclein variant 1 , Beta-synuclein

GENE ID SPEZIES
6620 Homo sapiens
104069 Mus musculus
113893 Rattus norvegicus
393944 Danio rerio
394467 Xenopus (Silurana) tropicalis
395391 Gallus gallus
479279 Canis lupus familiaris
495448 Xenopus laevis
508421 Bos taurus
619281 Takifugu rubripes
697484 Macaca mulatta
736255 Pan troglodytes
100127169 Sus scrofa
100190189 Taeniopygia guttata
100196630 Salmo salar
100354265 Oryctolagus cuniculus
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