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beta Synuclein Antikörper

SNCB Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7182802
  • Target Alle beta Synuclein (SNCB) Antikörper anzeigen
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Reaktivität
    • 50
    • 32
    • 32
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 6
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 62
    • 4
    Polyklonal
    Konjugat
    • 31
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser beta Synuclein Antikörper ist unkonjugiert
    Applikation
    • 36
    • 27
    • 25
    • 14
    • 14
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized peptide derived from Human Synuclein beta antibody.
    Isotyp
    IgG
  • Applikationshinweise
    WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    beta Synuclein (SNCB) (Synuclein, beta (SNCB))
    Andere Bezeichnung
    SNCB (SNCB Produkte)
    Synonyme
    AI838531 antikoerper, betaSYN antikoerper, zgc:66343 antikoerper, sncb antikoerper, MGC75784 antikoerper, LOC619281 antikoerper, SNCB antikoerper, syub antikoerper, synuclein beta antikoerper, synuclein, beta antikoerper, synuclein beta L homeolog antikoerper, Beta-synuclein antikoerper, SNCB antikoerper, Sncb antikoerper, sncb antikoerper, sncb.L antikoerper, syub antikoerper
    Hintergrund

    Background: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

    Yuxin Fan, Hum. Mol. Genet., Oct 2006, 15: 3002 - 3011.
    Makoto Hashimoto, J. Biol. Chem., May 2004, 279: 23622 - 23629.
    Cristine Alves da Costa, J. Biol. Chem., Sep 2003, 278: 37330 - 37335.
    Heather Snyder, J. Biol. Chem., Mar 2005, 280: 7562 - 7569.

    Aliases: 14 kDa brain-specific protein antibody, Beta-synuclein antibody, Phosphoneuroprotein 14 antibody, PNP14 antibody, Sncb antibody, Synuclein beta antibody, SYUB_HUMAN antibody

    UniProt
    Q16143
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