Sulfatase 2 Proteine (SULF2)

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Zusätzlich bieten wir Ihnen Sulfatase 2 Antikörper (92) und Sulfatase 2 Kits (23) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
SULF2 55959 Q8IWU5
SULF2 72043 Q8CFG0
Ratte SULF2 SULF2 311642  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Maus S tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage

SULF2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
Mouse (Murine) ,

Weitere Proteine zu Sulfatase 2 (SULF2) Interaktionspartnern

Zebrafish Sulfatase 2 (SULF2) Interaktionspartner

  1. Sulf2 expression is almost entirely restricted to the CNS.

Human Sulfatase 2 (SULF2) Interaktionspartner

  1. SULF2 promotes the growth and metastasis of CRC probably by activating Akt and Erk1/2 pathways.

  2. Although no change in SULF2 was detected in squamous cell carcinoma of the head and neck (HNSCC) serum, its detection in saliva (zeige RAG1AP1 Proteine) makes it worthy of further investigation as a potential HNSCC biomarker.

  3. results demonstrated that SULF2 can mediate the detrimental effects of ionizing radiation in vivo

  4. The short variants of Sulf2 promoted FGF2 (zeige FGF2 Proteine)-induced MDA-MB231 and MCF7 in vitro growth while full-length Sulf1 (zeige SULF1 Proteine) inhibited growth supporting in vivo mammary tumour cell signalling patterns of growth.

  5. Most pancreatic ductal adenocarcinomas had positive SULF2 staining in tumour cells and intratumoural or tumour-adjacent stroma. Elevated SULF2 in PDAC was associated with advanced tumour stage, vascular invasion, shorter interval to radiological progression and shorter overall survival.

  6. The SULF1/SULF2 (zeige SULF1 Proteine) activation thus does not only promote regulated foetal growth and injury-induced liver regeneration but also dysregulated tumour growth.

  7. Sulf2 facilitated lymphangiogenesis in breast cancer cells by regulating VEGF-D (zeige Figf Proteine) and that the AKT1related signaling pathway was involved.

  8. renal cell carcinoma (zeige MOK Proteine) with lower SULF-2 expression might have a higher potential for cell invasion and proliferation, leading to a poorer prognosis via the activation of VEGF (zeige VEGFA Proteine) and/or FGF signaling

  9. SULF2 is a multifaceted protein involved in triglyceride-rich lipoprotein homeostasis and angiogenesis. [review]

  10. Our data confirmed that Sulf2 promoted breast cancer progression and regulated the expression of tumor-related genes in breast cancer.

Mouse (Murine) Sulfatase 2 (SULF2) Interaktionspartner

  1. Sulf1 (zeige SULF1 Proteine) and Sulf2 play indispensable roles to maintain glomerular integrity and protective roles in diabetic nephropathy, probably by growth factor modulation.

  2. Expression of the heparan sulfate 6-O-endosulfatases, Sulf1 (zeige SULF1 Proteine) and Sulf2, in the avian and mammalian inner ear suggests a role for sulfation during inner ear development.

  3. It is proposed that Sulf1 (zeige SULF1 Proteine), Sulf2 and ErbB1 (zeige EGFR Proteine) are involved in the inhibition of neurite outgrowth and may regulate structural plasticity and regeneration in the nervous system.

  4. Sulf1 (zeige SULF1 Proteine)/, but not Sulf2/, mice, exhibited a marked delay in healing of corneal epithelial wounds.

  5. SULF2 regulates tissue regeneration in part via the activation of a novel WNT (zeige WNT2 Proteine)-GLI1 (zeige GLI1 Proteine)-CYCLIN D1 (zeige CCND1 Proteine) pathway.

  6. Sulf1 (zeige SULF1 Proteine) and Sulf2 differentially contribute to the generation of organ-specific sulfation patterns of heparan sulfate.

  7. Heparan sulfate sulfatase (zeige SGSH Proteine) SULF2 regulates PDGFRalpha signaling and growth in human and mouse malignant glioma

  8. Sulf-1 (zeige SULF1 Proteine) and Sulf-2 are essential regulators of GDNF signaling in the SSC (zeige CYP11A1 Proteine) niche and direct downstream targets of Sertoli cell-specific transcriptional factor Wilm's tumor 1.

  9. SULF2 is an unexpected suppressor of atherogenic lipoprotein clearance by hepatocytes

  10. These results reveal that Sulf1 (zeige SULF1 Proteine) and Sulf2 fulfil non-redundant functions in vivo in the development and maintenance of the murine nervous system.

Sulfatase 2 (SULF2) Protein Überblick

Protein Überblick

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005

Genbezeichner und Symbole assoziert mit Sulfatase 2 Proteine (SULF2)

  • sulfatase 2a (sulf2a)
  • sulfatase 2 (SULF2)
  • extracellular sulfatase Sulf-2 (LOC100540921)
  • sulfatase 2 (sulf2)
  • sulfatase 2b (sulf2b)
  • sulfatase 2 S homeolog (sulf2.S)
  • sulfatase 2 (Sulf2)
  • 2010004N24Rik Protein
  • AU020235 Protein
  • HSULF-2 Protein
  • mKIAA1247 Protein
  • MSulf-2 Protein
  • si:dkeyp-84g9.1 Protein
  • Sulf1 Protein
  • SULF2 Protein
  • wu:fb48e04 Protein
  • xtsulf2 Protein
  • zgc:55612 Protein

Bezeichner auf Proteinebene für Sulfatase 2 Proteine (SULF2)

sulfatase 2 , extracellular sulfatase Sulf-2-like , extracellular sulfatase Sulf-2 , sulf2a , sulfatase FP2a , sulfatase FP2b , sulfatase FP2

393910 Danio rerio
715937 Macaca mulatta
100029594 Monodelphis domestica
100056840 Equus caballus
100392416 Callithrix jacchus
100482124 Ailuropoda melanoleuca
100540921 Meleagris gallopavo
100559066 Anolis carolinensis
100587072 Nomascus leucogenys
322056 Danio rerio
55959 Homo sapiens
495271 Xenopus laevis
419209 Gallus gallus
477254 Canis lupus familiaris
533264 Bos taurus
72043 Mus musculus
311642 Rattus norvegicus
100152351 Sus scrofa
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