anti-Ring Finger and FYVE-Like Domain Containing 1 (RFFL) Antikörper

Has E3 ubiquitin protein ligase activity. Zusätzlich bieten wir Ihnen RFFL Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RFFL 67338 Q6ZQM0
RFFL 117584 Q8WZ73
RFFL 282844 Q8CIN9
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Top anti-RFFL Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RFFL Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: THP-1 cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Rffl Antibody Titration: 1.0 ug/ml Positive Control: Mouse Liver 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, IHC (p), WB   0.5 mg 4 bis 8 Tage
$715.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with RFFL antibody ABIN214375 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-RFFL antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg 11 bis 14 Tage
$484.00
Details
Pferd Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert RNAi, ELISA, WB Western Blot analysis of RFFL expression in transfected 293T cell line by RFFL monoclonal antibody (M01), clone 3A4.Lane 1: RFFL transfected lysate(36.6 KDa).Lane 2: Non-transfected lysate. Western blot analysis of RFFL over-expressed 293 cell line, cotransfected with RFFL Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with RFFL monoclonal antibody (M01), clone 3A4. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg 11 bis 12 Tage
$440.00
Details
Rind (Kuh) Kaninchen Unkonjugiert EIA, IF, IHC (p), WB 50 μg 6 bis 8 Tage
$495.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in A2058 cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot using  Protein A Purified anti-RFFL antibody shows detection of RFFL (arrowhead) in lysate. Lanes correspond to empty vector 293T cell lysate (mock, left); RNF34 transfected lysate (middle) and RFFL transfected lysate (right), are shown using 20 µl of lysate per lane. Lysates were prepared from equivalent numbers of cells. Data presented demonstrate that this reagent is specific for RFFL. After SDS-PAGE and transfer, the membrane was probed with the primary antibody diluted to 1:1,000 using 5% BLOTTO, 0.1% Tween-20 in PBS as the diluent. Incuba-tion occurred for 1 h at room temperature. Personal Communication, Srinivasa Srinivasula, CCR-NCI, Bethesda, MD. 500 μg 5 bis 7 Tage
$688.50
Details

Am meisten referenzierte anti-RFFL Antikörper

  1. Polyclonal RFFL Primary Antibody für IHC (p), ELISA - ABIN539474 : McDonald, El-Deiry: Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal RFFL Primary Antibody für WB - ABIN2775666 : Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses. in The Journal of biological chemistry 2014 (PubMed)

Weitere Antikörper gegen RFFL Interaktionspartner

Mouse (Murine) Ring Finger and FYVE-Like Domain Containing 1 (RFFL) Interaktionspartner

  1. EGF, which signals through CRAF, and an activated BRAF mutant also activate PKC and stimulate cell migration through up-regulating RFFL expression.

  2. Data show that the the amino-terminal domain of rififylin is critical for its recruitment to recycling endocytic membranes and for the inhibition of recycling.

  3. CARP2 [Rififylin] deficiency does not alter induction of NF-kappaB by TNFalpha.

Human Ring Finger and FYVE-Like Domain Containing 1 (RFFL) Interaktionspartner

  1. RFFL is an important regulator of voltage-gated hERG potassium channel activity and therefore cardiac repolarization and that this ubiquitination-mediated regulation requires parts of the ERAD pathway.

  2. it is interesting to note that a human lncRNA does exist within the 5'-UTR intronic region of the human RFFL gene . Given the rat data, our study may serve as a translational foundation for considering this human lncRNA as a candidate regulator for cardiovascular diseases.

  3. EGF, which signals through CRAF, and an activated BRAF mutant also activate PKC and stimulate cell migration through up-regulating RFFL expression.

  4. data indicate AE induces caspase-8-mediated activation of mitochondrial death pathways by decreasing the stability of CARP mRNAs in a p53-independent manner.

  5. CARPs together with MDM2 enhance p53 degradation, thereby inhibiting p53-mediated cell death.

  6. acts at the level of endocytic vesicles to limit the intensity of TNF-induced NF-kappaB activation by the regulated elimination of a necessary signaling component within the receptor complex

RFFL Antigen-Profil

Protein Überblick

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

Genbezeichner und Symbole assoziert mit RFFL

  • ring finger and FYVE like domain containing E3 ubiquitin protein ligase (RFFL) Antikörper
  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog (rffl.L) Antikörper
  • ring finger and FYVE-like domain containing 1 (Rffl) Antikörper
  • ring finger and FYVE like domain containing protein (Rffl) Antikörper
  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl) Antikörper
  • 1700051E09Rik Antikörper
  • 4930516L10Rik Antikörper
  • BG080975 Antikörper
  • CARP-2 Antikörper
  • CARP2 Antikörper
  • FRING Antikörper
  • MGC84042 Antikörper
  • Rffl Antikörper
  • RIFIFYLIN Antikörper
  • RNF34L Antikörper
  • RNF189 Antikörper

Bezeichner auf Proteinebene für RFFL

E3 ubiquitin-protein ligase rififylin , ring finger and FYVE-like domain containing 1 , rififylin , e3 ubiquitin-protein ligase rififylin-like , RING finger and FYVE-like domain-containing protein 1 , fring , FYVE-RING finger protein SAKURA , RING finger protein 189 , caspase regulator CARP2 , caspases-8 and -10-associated RING finger protein 2 , FYVE-RING finger protein Sakura , RING finger protein SAKURA , ring finger and FYVE like domain containing protein

GENE ID SPEZIES
417529 Gallus gallus
447349 Xenopus laevis
454582 Pan troglodytes
491144 Canis lupus familiaris
530263 Bos taurus
100058179 Equus caballus
100115488 Nasonia vitripennis
100464760 Ailuropoda melanoleuca
100604408 Nomascus leucogenys
67338 Mus musculus
117584 Homo sapiens
282844 Rattus norvegicus
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