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RFFL Produkte

(Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

Kategorien

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

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Ausgewählte RFFL Kategorien

RFFL Antikörper

High quality antibodies with extensive validation data.

RFFL Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene RFFL Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, RNAi
Validierungen
  • (4)
Kat. Nr. ABIN566759
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7151117
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (5)
  • (1)
Kat. Nr. ABIN1881744
Menge 400 μL
Datenblatt Datenblatt

Empfohlene RFFL ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6221029
Menge 96 tests
Datenblatt Datenblatt

Empfohlene RFFL Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317849
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1317851
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3095003
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren RFFL Produkten

Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." in: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Newton-Cheh, Eijgelsheim, Rice, de Bakker, Yin, Estrada, Bis, Marciante, Rivadeneira, Noseworthy, Sotoodehnia, Smith, Rotter, Kors, Witteman, Hofman, Heckbert: "Common variants at ten loci influence QT interval duration in the QTGEN Study." in: Nature genetics, Vol. 41, Issue 4, pp. 399-406, (2009) (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).

Liao, Xiao, Tchikov, Fujita, Yang, Wincovitch, Garfield, Conze, El-Deiry, Schütze, Srinivasula: "CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation." in: Current biology : CB, Vol. 18, Issue 9, pp. 641-9, (2008) (PubMed).

Yang, Dicker, Chen, El-Deiry: "CARPs enhance p53 turnover by degrading 14-3-3sigma and stabilizing MDM2." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 5, pp. 670-82, (2008) (PubMed).

McDonald, El-Deiry: "Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 16, pp. 6170-5, (2004) (PubMed).

Coumailleau, Das, Alcover, Raposo, Vandormael-Pournin, Le Bras, Baldacci, Dautry-Varsat, Babinet, Cohen-Tannoudji: "Over-expression of Rififylin, a new RING finger and FYVE-like domain-containing protein, inhibits recycling from the endocytic recycling compartment." in: Molecular biology of the cell, Vol. 15, Issue 10, pp. 4444-56, (2004) (PubMed).

Tibbetts, Shiozaki, Gu, McDonald, El-Deiry, Shi: "Crystal structure of a FYVE-type zinc finger domain from the caspase regulator CARP2." in: Structure (London, England : 1993), Vol. 12, Issue 12, pp. 2257-63, (2004) (PubMed).

Synonyme und alternative Namen zu RFFL

ring finger and FYVE like domain containing E3 ubiquitin protein ligase (RFFL), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase L homeolog (rffl.L), ring finger and FYVE-like domain containing 1 (Rffl), ring finger and FYVE like domain containing protein (Rffl), ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl), 1700051E09Rik, 4930516L10Rik, BG080975, CARP-2, Carp2, CARP2, FRING, MGC84042, RFFL, Rffl, RIFIFYLIN, RNF34L, RNF189

Bezeichner auf Proteinebene für RFFL

  • E3 ubiquitin-protein ligase rififylin
  • ring finger and FYVE-like domain containing 1
  • rififylin
  • e3 ubiquitin-protein ligase rififylin-like
  • RING finger and FYVE-like domain-containing protein 1
  • fring
  • FYVE-RING finger protein SAKURA
  • RING finger protein 189
  • caspase regulator CARP2
  • caspases-8 and -10-associated RING finger protein 2
  • FYVE-RING finger protein Sakura
  • RING finger protein SAKURA
  • ring finger and FYVE like domain containing protein
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