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The protein encoded by RIPK4 is a serine/threonine protein kinase that interacts with protein kinase C-delta. Zusätzlich bieten wir Ihnen RIPK4 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 56 products:
Human Monoclonal RIPK4 Primary Antibody für ELISA, WB - ABIN565712
Adams, Munz: RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair. in Experimental cell research 2009
Data show that the SCF (zeige KITLG Antikörper)(beta-TrCP (zeige BTRC Antikörper)) ubiquitin E3 ligase complex responsible for regulating the active protein kinase C-associated kinase (RIPK4) level.
Silencing RIPK4 promoted the proliferation and inhibited the apoptosis of chondrocytes. In addition, silencing RIPK4 blocked the Wnt/betacatenin signaling pathway, thus contributing to alleviating the osteoarthritis pathogenesis.
RIPK4 was upregulated in the subgroup of pancreatic cancer with a high metastatic potential
A20 (zeige TNFAIP3 Antikörper) regulates canonical wnt (zeige WNT2 Antikörper)-signaling through an interaction with RIPK4
that loss of RIP4 enhances STAT3 (zeige STAT3 Antikörper) signaling in lung cancer cells
The patient with CHAND syndrome harbored the same mutation as the one identified in the family previously reported. We thus confirm the implication of RIPK4 gene in CHAND syndrome in addition to Bartsocas-Papas (zeige PSTPIP1 Antikörper) syndrome and discuss genotype/phenotype correlations.
CCL5 (zeige CCL5 Antikörper) and CXCL11 (zeige CXCL11 Antikörper) expression were also induced in response to the activation of the PKC (zeige PRRT2 Antikörper) pathway, and gene silencing experiments indicated that their inducible expression was dependent on RIPK4 and IRF6 (zeige IRF6 Antikörper). Moreover, gene reporter assays suggested that RIPK4 induces CCL5 (zeige CCL5 Antikörper) and CXCL11 (zeige CXCL11 Antikörper) expression by stimulating the transactivation of their promoters by IRF6 (zeige IRF6 Antikörper).
Overexpression of EZH2 (zeige EZH2 Antikörper) was found in 30 patients (76.9%) and was associated with FIGO stage, histological type, and lymph node metastasis (p < 0.05). In conclusion, our data suggest that RIPK4/EZH2 (zeige EZH2 Antikörper) markers might be used as potential predictors of prognosis in cervical cancer.
These findings position RIPK4 upstream of a hierarchal IRF6 (zeige IRF6 Antikörper)-GRHL3 (zeige GRHL3 Antikörper)-ELF3 (zeige ELF3 Antikörper) transcription factor pathway in keratinocytes.
CHAND and Bartsocas-Papas (zeige PSTPIP1 Antikörper) syndrome might be allelic disorders or RIPK4 mutations could confer varying degrees of phenotypic severity, depending on their localization within or outside functionally important domains.
We further define the interactions of keratinocyte PKK with TP63 (zeige TP63 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) signaling, highlighting the importance of this protein as a tumor suppressor in skin squamous cell carcinoma development.
this work uncovers a critical role of PKK in lupus development
these results reveal a critical role of PKK in the maintenance of recirculating mature B cells as well as the development of B1 cells in mice
This approach identified a key signaling event, phosphorylation of a desmosome component, PKP1 (plakophilin-1 (zeige PKP1 Antikörper)) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal differentiation.
RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation
a member of the RICK/RIP (zeige HRB Antikörper) family of kinases, which is involved in a PKC-activated NF-kappa B (zeige NFKB1 Antikörper) signaling pathway that is independent of Bcl10 (zeige BCL10 Antikörper) and IKK gamma (zeige IKBKG Antikörper)
Data show that RIP4 is a critical component of a novel pathway that controls keratinocyte differentiation.
PKK may be required early in B cell development and for B cell receptor-mediated B cell proliferation.
PKK is not required for the production of B cells in the bone marrow or for the development and maintenance of all mature B lymphocyte (zeige AKAP17A Antikörper) populations.
NF-kappaB (zeige NFKB1 Antikörper) activity and keratinocyte differentiation are regulated by the RIP4 protein, which has roles in cutaneous wound repair
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
ankyrin repeat domain 3
, protein kinase PKK
, receptor-interacting serine/threonine-protein kinase 4
, receptor-interacting serine-threonine kinase 4
, receptor-interacting serine/threonine-protein kinase 4-like
, PKC-delta-interacting protein kinase
, ankyrin repeat domain-containing protein 3
, protein kinase C-associated kinase
, serine/threonine-protein kinase ANKRD3
, PKC-associated protein kinase
, PKC-regulated protein kinase