Protocadherin gamma Subfamily C, 5 Proteine (PCDHGC5)

PCDHGC5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.

alle Proteine anzeigen Gen GeneID UniProt
Human PCDHGC5 PCDHGC5 56097 Q9Y5F6
Maus PCDHGC5 PCDHGC5 93708  
Ratte PCDHGC5 PCDHGC5 641525  
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
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Weitere Proteine zu Protocadherin gamma Subfamily C, 5 (PCDHGC5) Interaktionspartnern

Mouse (Murine) Protocadherin gamma Subfamily C, 5 (PCDHGC5) Interaktionspartner

  1. C-terminal cytoplasmic fragment of PcdhgC5 acts as a scaffold for CaMKP (zeige PPM1F Proteine) and CaMKI (zeige CAMK1 Proteine) to regulate CaMKP (zeige PPM1F Proteine) activity.

Protocadherin gamma Subfamily C, 5 (PCDHGC5) Protein Überblick

Protein Überblick

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Genbezeichner und Symbole assoziert mit PCDHGC5

  • protocadherin gamma subfamily C, 5 (PCDHGC5)
  • protocadherin gamma subfamily C, 5 (Pcdhgc5)
  • PCDH-GAMMA-C5 Protein

Bezeichner auf Proteinebene für PCDHGC5

protocadherin gamma-C5 , protocadherin gamma c5 , PCDH-gamma-C5

GENE ID SPEZIES
56097 Homo sapiens
93708 Mus musculus
520024 Bos taurus
641525 Rattus norvegicus
100034697 Pan troglodytes
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