Protocadherin gamma Subfamily B, 4 Proteine (PCDHGB4)

PCDHGB4 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five.

alle Proteine anzeigen Gen GeneID UniProt
Ratte PCDHGB4 PCDHGB4 291635  
Human PCDHGB4 PCDHGB4 8641 Q9UN71
Maus PCDHGB4 PCDHGB4 93701  
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 2 bis 3 Tage
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
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Protocadherin gamma Subfamily B, 4 (PCDHGB4) Protein Überblick

Protein Überblick

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes.

Genbezeichner und Symbole assoziert mit PCDHGB4

  • protocadherin gamma subfamily A, 7 (Pcdhga7)
  • protocadherin gamma subfamily B, 4 (PCDHGB4)
  • protocadherin gamma subfamily B, 4 (Pcdhgb4)
  • CDH20 Protein
  • FIB2 Protein
  • PCDH-GAMMA-B4 Protein
  • PCDHGB4 Protein

Bezeichner auf Proteinebene für PCDHGB4

protocadherin gamma-A7 , cadherin 20 , cadherin-20 , fibroblast cadherin FIB2 , fibroblast cadherin-2 , protocadherin gamma-B4 , protocadherin gamma C-VI

GENE ID SPEZIES
291635 Rattus norvegicus
8641 Homo sapiens
93701 Mus musculus
100034687 Pan troglodytes
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