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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Zusätzlich bieten wir Ihnen Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 4 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 64 products:
Mammalian Monoclonal KCNA4 Primary Antibody für ISt, IHC - ABIN1304751
Pott, Ren, Tran, Yang, Henderson, Jordan, Roos, Garfinkel, Philipson, Goldhaber: Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice. in American journal of physiology. Cell physiology 2007
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Human Polyclonal KCNA4 Primary Antibody für WB - ABIN1881472
Lee, Lee, Choi, Yoon, Pyo, Shin, Choi, Lim, Rhim, Won, Lim, Choe, Kim, Kim, Nah: Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue. in Molecular pharmacology 2008
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Expression of Kv1.4 appears to increase in the spinal cord of mice modelling remitting-relapsing experimental allergic encephalomyelitis (rrEAE) in peak and remitting phases.
Detection of the methylation prevalence of KCNA4 and CYP26B1 (zeige CYP26B1 Antikörper) together in serum demonstrated the good sensitivity and specificityin gastric cancer
Data suggest that episodic ataxia type 1 mutations affect fast inactivation of Kv1.1 (zeige KCNA1 Antikörper)/1.4 channels by a reduction in either subunit surface expression or altered affinity for the inactivation domain.
Sialylated N-glycans uniquely impact gating of a mammalian Shaker family K(v) channel isoform, K(v)1.5 (zeige KCNA5 Antikörper), but have no effect on gating of a second Shaker isoform, K(v)1.4.
Results describe an erbstatin (Erb (zeige ESR2 Antikörper)) analogue as a small molecule inhibitor of the N-type inactivation in potassium channels Kv1.4 and Kv1.1 (zeige KCNA1 Antikörper)+Kvbeta1 (zeige KCNAB1 Antikörper).
Novel role for GIP (zeige GIP Antikörper) in regulating K(V)1.4 cell surface expression and modulation of A-type potassium currents
Fast inactivation in human Kv1.4 is modulated by structural elements in the C-terminus, suggesting that the process involves the concerted action of the N- and C-termini.
The results demonstrate that the human Kvbeta1.1 (zeige KCNAB1 Antikörper) and Kvbeta1.2 subunits regulate the proportion of wild-type Kv1.4-1.1 channels that are available to open.
Ginsenoside Rg3 inhibits KV1.4 channel currents by interacting with the lysine531 residue.
Thr (zeige TRH Antikörper)-330 of Kv1.4 serves to interlock the voltage-sensing and gating domains of adjacent monomers, thereby yielding a structure competent for the surface expression of functional tetramers
Data show that suprachiasmatic nucleus (SCN (zeige SRI Antikörper)) explants from potassium channel (zeige KCNAB2 Antikörper) Kv1.4(-/-)period2 protein Per2 (zeige PER2 Antikörper)(Luc) and potassium channel Kv4.2 (zeige KCND2 Antikörper)(-/-) period2 protein Per2 (zeige PER2 Antikörper)(Luc) mice have significantly shorter circadian periods in PER2 (zeige PER2 Antikörper) rhythms.
Increased A-type K(+) currents and expression of voltage-gated potassium channel (zeige KCNQ1 Antikörper) Kcna4 (Kv1.4) in SNS (zeige SCN10A Antikörper)-gp130 (zeige LRPPRC Antikörper)(-/-) nociceptors.
The experiments here demonstrate that Kv4.2 (zeige KCND2 Antikörper), Kv4.3 (zeige KCND3 Antikörper) and Kv1.4 all contribute to the generation of potassium channels in mature cortical pyramidal (CP) neurons; these channels play distinct roles in regulating the intrinsic properties of mature CP neurons.
Kv1.4- and Kv4.2 (zeige KCND2 Antikörper)-encoded I(A) channels regulate the intrinsic excitability of SCN (zeige SRI Antikörper) neurons during the day and night and determine the period and amplitude of circadian rhythms in SCN (zeige SRI Antikörper) neuron firing and locomotor behavior.
This study demonistrated that Kcna4 gene expression in mouse dorsal raphe nucleus
Targeted deletion of Kv1.4 alpha-subunit (zeige POLG Antikörper) (along with Kv4.2 (zeige KCND2 Antikörper) and Kv4.3 (zeige KCND3 Antikörper)) demonstrates that individual alpha-subunits encode for the I(A) current in cortical pyramidal neurons.
PSD-95 (zeige DLG4 Antikörper) increased the amount of Kv1.4, but not Kv4.2 (zeige KCND2 Antikörper), in lipid rafts.
Data indicate that Kv1.4 expression is mediated through a complex interplay between many distinct RNA regions.
Pituitary adenylate cyclase activating polypeptide (zeige ADCYAP1 Antikörper) reduces kv1.4 epression in olfactory bulb.
In experimental autoimmune encephalomyelitis, Kv1.4 immunoreactivity was detected in or around lesions already during disease onset with a peak early and a subsequent decrease in the late phase of the disease.
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.
Kv1.4 voltage-gated potassium channel
, potassium channel alpha subunit Kv1.4
, potassium voltage-gated channel, shaker-related subfamily, member 4
, potassium channel Shaker alpha subunit variant cKv1.4(m)
, Kv1.4 potassium channel
, potassium voltage gated channel, shaker related subfamily, member 4
, potassium voltage-gated channel subfamily A member 4
, voltage-gated potassium channel subunit Kv1.4
, cardiac potassium channel
, fetal skeletal muscle potassium channel
, potassium channel 2
, rapidly inactivating potassium channel
, shaker-related potassium channel Kv1.4
, type A potassium channel
, voltage-gated K(+) channel HuKII
, voltage-gated potassium channel HBK4
, voltage-gated potassium channel HK1
, potassium voltage-gated channel, shaker-related subfamily, memeber 4