Peptidase Inhibitor 3, Skin-Derived Proteine (PI3)

PI3 encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. Zusätzlich bieten wir Ihnen Peptidase Inhibitor 3, Skin-Derived Antikörper (75) und Peptidase Inhibitor 3, Skin-Derived Kits (37) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PI3 5266 P19957
Maus PI3 PI3 20702 Q00896
Ratte PI3 PI3 408230  
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Top Peptidase Inhibitor 3, Skin-Derived Proteine auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Mammalian Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
Details
HOST_HEK-293T Cells Human His-DYKDDDDK-Strep II Tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$614.87
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,165.17
Details
Baculovirus infected Insect Cells Human His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$492.31
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
Details

PI3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , , ,
, , ,

Weitere Proteine zu Peptidase Inhibitor 3, Skin-Derived (PI3) Interaktionspartnern

Human Peptidase Inhibitor 3, Skin-Derived (PI3) Interaktionspartner

  1. Elafin decreased in active patients with inflammatory bowel disease and was negatively correlated with disease activity, suggesting that elafin may play a protective role

  2. Plasma Neutrophil Elastase (zeige ELANE Proteine) and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome

  3. UV phototoxicity-induced pre-elafin inside keratinocytes prior to cornified envelope formation could be involved in UV-induced keratinocyte apoptosis via cystatin-A (zeige CSTA Proteine) downregulation resulting in pro-caspase-3 (zeige CASP3 Proteine) activation.

  4. Recombinant human elafin promotes alveologenesis in newborn mice exposed to chronic hyperoxia

  5. Our study revealed that high elafin levels identified in smoking- and asthma-related microarray data sets and an epidemiologic study significantly reduced the risk of asthma.

  6. The expression of elafin in fallopian tubes of ectopic pregnancies is reduced.

  7. The elevations in cervical elafin and SLPI (zeige SLPI Proteine) expression in the women with preterm delivery might reflect the local response to the pathogen invasion into the cervix preceding preterm labor.

  8. PI3 expression was downregulated in 24% of DCIS and 83% of invasive breast tumors. PI3 was also downregulated in 33% of ovarian cystadenomas, 43% of borderline ovarian tumors, and 86% of invasive ovarian carcinomas.

  9. The imbalance between neutrophil elastase (zeige ELANE Proteine) and its inhibitors, such as elafin, presents an important therapeutic target in breast cancer.

  10. Higher urinary elafin levels are associated with an increased risk of micro- and macroalbuminuria, acute kidney injury and chronic kidney disease, and death after hematopoietic stem cell transplantation.

Mouse (Murine) Peptidase Inhibitor 3, Skin-Derived (PI3) Interaktionspartner

  1. Trappin-2 may therefore play an important role in innate recognition and clearance of pathogens during the very earliest stages of pulmonary infection.

Peptidase Inhibitor 3, Skin-Derived (PI3) Protein Überblick

Protein Überblick

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.

Genbezeichner und Symbole assoziert mit PI3

  • peptidase inhibitor 3 (PI3)
  • serine (or cysteine) peptidase inhibitor, clade A, member 1C (Serpina1c)
  • peptidase inhibitor 3, skin-derived (SKALP) (PI3)
  • WAP four-disulfide core domain 15B (Wfdc15b)
  • cementoin Protein
  • elafin Protein
  • ESI Protein
  • Pi3 Protein
  • Pi6 Protein
  • Serpina1c Protein
  • Skalp Protein
  • Spi1-3 Protein
  • Spi1-6 Protein
  • TRAPPIN-2 Protein
  • Wap3 Protein
  • Wfdc14 Protein

Bezeichner auf Proteinebene für PI3

PI-3 , WAP four-disulfide core domain 14 , WAP four-disulfide core domain protein 14 , elafin , elastase-specific inhibitor , pre-elafin , protease inhibitor 3, skin-derived (SKALP) , protease inhibitor WAP3 , skin-derived antileukoproteinase , trappin-2 , elafin preproprotein , peptidase inhibitor 3, skin-derived (SKALP) , TRAPPIN-2 protein , trappin ovine homolog , peptidase inhibitor 3, skin-derived , alpha-1 protease inhibitor 3 , alpha-1 protease inhibitor 6 , alpha-1-antitrypsin 1-3 , alpha-1-antitrypsin 1-6 , apha-1 protease inhibitor 3 , serine (or cysteine) proteinase inhibitor, clade A, member 1c , serine protease inhibitor 1-3 , serine protease inhibitor 1-6 , serine protease inhibitor A1c , serpin A1c , WAP four-disulfide core domain protein 15B , WAP-type four-disulfide core 14 , protease inhibitor 3, skin-derived , trappin 8

GENE ID SPEZIES
5266 Homo sapiens
458276 Pan troglodytes
477241 Canis lupus familiaris
574237 Macaca mulatta
641305 Ovis aries
100137037 Pongo abelii
100137495 Papio anubis
20702 Mus musculus
783871 Bos taurus
408230 Rattus norvegicus
396757 Sus scrofa
102172734 Capra hircus
101752219 Gallus gallus
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