anti-Pappalysin 2 (PAPPA2) Antikörper

Metalloproteinase which specifically cleaves IGFBP-5. Zusätzlich bieten wir Ihnen Pappalysin 2 Kits (28) und Pappalysin 2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAPPA2 23850  
PAPPA2 60676 Q9BXP8
PAPPA2 680415  
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Top anti-Pappalysin 2 Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PAPPA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB <b>WB Suggested Anti-PAPPA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Rat Placenta lysate; Primary Ab: 2µg/ml Rabbit Anti-Human PAPPA2 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western Blot: Pappalysin-2/PAPP-A2 Antibody [NBP1-76487] - HeLa cell lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide. Immunocytochemistry/Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody [NBP1-76487] - Immunofluorescence of PAPP A2 in HeLa cells with PAPP A2 antibody at 20 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details

PAPPA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Pappalysin 2 Interaktionspartner

Mouse (Murine) Pappalysin 2 (PAPPA2) Interaktionspartner

  1. This review evaluates the current data concerning PAPP-A2 function, and particularly the effect of PAPP-A2 mutation on growth.

  2. Locally-produced Pappa2 in osteoblasts, epiphysis, and metaphysis, is required for normal postnatal bone growth.

  3. Despite a dramatic disruption of the balance between circulating IGF-I (zeige IGF1 Antikörper), IGFBP-3 (zeige IGFBP3 Antikörper) and -5, we found no effects of Pappa2 deletion on glucose metabolism, weight gain or adiposity on a high-fat diet.

  4. Pappa2 deletion had no effect on female reproduction and subtle effects on male fertility.

  5. Pappa2 is responsible for the effects of the previously-identified QTL, demonstrating that natural variation in the Pappa2 gene contributes to variation in postnatal growth in mice

  6. investigation of biological role of PAPP-A2 using knockout mice, heterozygotes, primary fibroblasts: The most striking phenotype of PAPP-A2 KO mice was postnatal growth retardation. PAPP-A2 KO mice were fertile, but exhibited compromised fecundity.

  7. Elevated PAPPA2 levels are a consequence rather than a cause of pregnancy complications.

  8. The refinement of the target region to four genes and the finding that the QTL affects IGFBP-5 (zeige IGFBP5 Antikörper) levels suggest that PAPPA2 may be involved with normal postnatal growth

  9. Pappa2 expression also shows specific localization within the mouse embryo and therefore may play roles in fetal development, independent of its action in the placenta

Human Pappalysin 2 (PAPPA2) Interaktionspartner

  1. This review evaluates the current data concerning PAPP-A2 function, and particularly the effect of PAPP-A2 mutation on growth.

  2. These patients provide important insights into the regulation of longitudinal growth in humans, documenting the critical role of PAPP-A2 in releasing IGF-I (zeige IGF1 Antikörper) from its binding proteins.

  3. Short-term treatment with progressive doses of rhIGF1 (recombinant human insulin-like growth factor-1 (zeige IGF1 Antikörper)) improved growth in two siblings with deficiency of PAPP-A2 (pregnancy-associated plasma protein-A2) [due to a homozygous loss-of-function frameshift mutation in exon 3 of the PAPP-A2 gene (p.D643fs25*)] that resulted in postnatal growth failure due to resulting decrease in IGF1 (zeige IGF1 Antikörper) bioavailability. [CASE REPORT]

  4. in situ hybridization (ISH (zeige ANTXR2 Antikörper)) and immunohistochemistry (IHC) were employed to examine the spatial and temporal expression of PAPPA2 in the human fetomaternal interface.

  5. PAPP-A2 is differentially expressed in different trophoblast populations and shows strong down regulation in the mid second trimester in chorionic villous samples.

  6. The association between this PAPPA2 single nucleotide polymorphism and developmental dysplasia of the hip was evaluated.

  7. The upregulation of PAPP-A2 observed in preeclampsia at term occurs early in pregnancy, before the symptoms develop.

  8. PAPPA2 may be upregulated in severe pre-eclampsia and, functionally, this may be mediated via increased placental hypoxia known to occur with this pregnancy disorder.

  9. The existence of this assay will enable an assessment of the biomarker potential of PAPP-A2 in pre-eclampsia as well as other clinical conditions.

  10. Association of a single nucleotide polymorphism in pregnancy-associated plasma protein-A2 with developmental dysplasia of the hip

Cow (Bovine) Pappalysin 2 (PAPPA2) Interaktionspartner

  1. Variants in the pregnancy-associated plasma protein-A2 gene on Bos taurus autosome 16 are associated with daughter calving ease and productive life in Holstein cattle.

Zebrafish Pappalysin 2 (PAPPA2) Interaktionspartner

  1. Papp-a2 modulates Bmp and Notch (zeige NOTCH1 Antikörper) signaling by independent mechanisms in zebrafish embryos to control cranial cartilage development and angiogenesis.

Pappalysin 2 (PAPPA2) Antigen-Profil

Protein Überblick

Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.

Genbezeichner und Symbole assoziert mit anti-Pappalysin 2 (PAPPA2) Antikörper

  • pappalysin 2 (Pappa2) Antikörper
  • pappalysin 2 (PAPPA2) Antikörper
  • pappalysin 2 (pappa2) Antikörper
  • PAPP-A2 Antikörper
  • PAPP-E Antikörper
  • PAPPE Antikörper
  • PLAC3 Antikörper
  • si:dkey-39f8.1 Antikörper

Bezeichner auf Proteinebene für anti-Pappalysin 2 (PAPPA2) Antikörper

placenta-specific 3 , pregnancy-associated plasma preproprotein-A2 , pregnancy-associated plasma protein-E , pappalysin-2 , pregnancy-associated plasma protein E1 , pappalysin 2 , pappalysin-2-like

GENE ID SPEZIES
23850 Mus musculus
60676 Homo sapiens
429071 Gallus gallus
457543 Pan troglodytes
480058 Canis lupus familiaris
538320 Bos taurus
567038 Danio rerio
100021506 Monodelphis domestica
100052718 Equus caballus
100447000 Pongo abelii
100468592 Ailuropoda melanoleuca
100491868 Xenopus (Silurana) tropicalis
100521390 Sus scrofa
100567326 Anolis carolinensis
100582901 Nomascus leucogenys
100357077 Oryctolagus cuniculus
100736235 Cavia porcellus
101118205 Ovis aries
680415 Rattus norvegicus
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