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The protein encoded by PANX2 belongs to the innexin family. Zusätzlich bieten wir Ihnen Pannexin 2 Proteine (6) und Pannexin 2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal PANX2 Primary Antibody für IHC, WB - ABIN2775571
Baranova, Ivanov, Petrash, Pestova, Skoblov, Kelmanson, Shagin, Nazarenko, Geraymovych, Litvin, Tiunova, Born, Usman, Staroverov, Lukyanov, Panchin: The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. in Genomics 2004
Show all 6 Pubmed References
Mammalian Monoclonal PANX2 Primary Antibody für ISt, IHC - ABIN1304906
Le Vasseur, Lelowski, Bechberger, Sin, Naus: Pannexin 2 protein expression is not restricted to the CNS. in Frontiers in cellular neuroscience 2014
All three pannexins Panx1 (zeige PANX1 Antikörper), Panx2, and Panx3 (zeige PANX3 Antikörper) mRNAs were expressed in all of the analyzed undifferentiated stem cell lines.
Panx2 mRNA and protein levels were only upregulated in focal cortical dysplasia type IIb lesions of intractable epilepsy patients and characteristically expressed on SOX2 (zeige SOX2 Antikörper)-positive multipotential balloon cells.
Panx2 is an important regulator of the insulin (zeige INS Antikörper) secretory capacity and apoptosis in pancreatic beta-cells.
The results of this study do not support a major contribution of PANX1 (zeige PANX1 Antikörper)-3 to disease risk of schizophrenia according to DSM-5.
There is dense expression of Panx2 in the enteric nervous system. The substantial increase in Panx2 mRNA in ulcerative colitis (UC) muscle but not protein suggests that the Panx2 translation process may be disrupted in UC.
Data suggest that both up-regulation and down-regulation of expression of pannexins (PANX1 (zeige PANX1 Antikörper), PANX2, PANX3 (zeige PANX3 Antikörper)) are associated with disease onset and/or progression; examples include neoplasms, multiple sclerosis, migraine, and hypertension. [REVIEW]
Panx1 (zeige PANX1 Antikörper) and Panx2 expression was detected in the temporal lobe cortex of patients with temporal lobe epilepsy and in the control tissues.
Pannexin1 (zeige PANX1 Antikörper) and Pannexin2 channels show quaternary similarities to connexons and different oligomerization numbers from each other
These data do not suggest that Panx2 or Cx36 (zeige GJD2 Antikörper) could increase the risk of schizophrenia in the Japanese population.
According to brain cancer gene expression database REMBRANDT, PANX2 expression levels can predict post diagnosis survival for patients with glial tumors.
It used overlap-extension cloning to create the first chimeric Panx, consisting of Panx2 with the Panx1 (zeige PANX1 Antikörper) C-terminus (Panx2(Panx1CT)), to determine whether the Panx1 (zeige PANX1 Antikörper) C-terminus influences the trafficking of Panx2.
). Pannexin double-knockout mice (Px1 (zeige PANX1 Antikörper)(-/-) Px2(-/-)) were less impaired in parameters such as exploration, anxiety, sensorimotor function and behavioral symmetry.
In situ hybridization revealed that mRNAs for Panx1 (zeige PANX1 Antikörper) and Panx2 were both expressed in the olfactory epithelium and olfactory bulb.
Px1 (zeige PANX1 Antikörper) and Px2 underlie channel function in neurons and contribute to ischemic brain damage
Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment
Panx2 strongly interacts with the core and high-mannose species of Panx1 (zeige PANX1 Antikörper) but not with Panx3 (zeige PANX3 Antikörper). The combination of Panx1 (zeige PANX1 Antikörper) & Panx2 results in compromised channel function.
Results reveal a widespread and similar mRNA distribution for both pannexin 1 (zeige PANX1 Antikörper) and 2, but indicate that they are inversely regulated during the development of the rat brain.
Panx1 (zeige PANX1 Antikörper) and Panx2 are abundantly expressed in the retina, and may therefore contribute to the electrical and metabolic coupling, or to signaling between retinal neurons
Data show that Panx2 is expressed in the spiral and Scarpa's ganglion neurons.
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene.