anti-Pannexin 1 (PANX1) Antikörper

The protein encoded by PANX1 belongs to the innexin family. Zusätzlich bieten wir Ihnen Pannexin 1 Kits (15) und Pannexin 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PANX1 24145 Q96RD7
PANX1 55991 Q9JIP4
PANX1 315435 P60570
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Top anti-Pannexin 1 Antikörper auf

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-PANX1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IF, ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Pannexin 1 Antibody [NBP1-92241] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: Pannexin 1 Antibody [NBP1-92241] - Staining of human cell line A-431 shows positivity in plasma membrane. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB PANX1 Antibody (Center)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the PANX1 antibody detected the PANX1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of PANX1 using COLO205 whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry: Pannexin-1 Antibody [NBP1-59672] - Paraffin Embedded Tissue: Human neural cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0 - 8.0 ug/ml Magnification: 400X Immunohistochemistry: Pannexin-1 Antibody [NBP1-59672] - Human Jurkat cell lysate Antibody Dilution: 1.0 ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen Verfügbar
Ratte Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Rat Stomach Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage

Weitere Antikörper gegen Pannexin 1 Interaktionspartner

Zebrafish Pannexin 1 (PANX1) Interaktionspartner

  1. Extracellular ATP hydrolysis via NTPDase1 (zeige ENTPD1 Antikörper) action inhibits synaptic transmission by pannexin 1-mediated increase in pH buffering of the synaptic cleft.

  2. The existence of two Panx1 proteins in zebrafish displaying distinct tissue distribution, protein modification and electrophysiological properties, suggests that both proteins fulfill different functions in vivo.

  3. The function of panx1 channel is significantly reduced following mutation of a single cysteine residue (C282W) in the fourth transmembrane region of panx1.

Human Pannexin 1 (PANX1) Interaktionspartner

  1. Progressive PANX1 channel opening is directly linked to permeation of ions and large and occurs during both irreversible and reversible forms of channel activation. This unique, quantized activation process enables fine tuning of PANX1 channel activity and may be a generalized regulatory mechanism for other related multimeric channels.

  2. authors proposed a tentative intracellular signaling pathway of the acetylcholine-induced ciliary beat, in which the pannexin-1-purinergic P2X receptor unit may play a central role in ciliary beat regulation

  3. These results newly identify Pannexin-1 as a protein highly expressed in human dermal lymphatic endothelial cells.

  4. The pannexin 2 (Panx2 (zeige PANX2 Antikörper)) N86Q mutant is glycosylation-deficient and tends to aggregate in the endoplasmic reticulum (ER)reducing its cell surface trafficking but it can still interact with pannexin 1 (Panx1).

  5. All three pannexins Panx1, Panx2 (zeige PANX2 Antikörper), and Panx3 (zeige PANX3 Antikörper) mRNAs were expressed in all of the analyzed undifferentiated stem cell lines.

  6. Pannexin1 (Panx1) was suggested to be functionally associated with purinergic P2X and N-methyl-D-aspartate (NMDA) receptor channels. Activation of these receptor channels by their endogenous ligands leads to cross-activation of Panx1 channels. This in turn potentiates P2X and NMDA receptor channel signaling.

  7. The ubiquitous expression, as well as its function as a major ATP release and nucleotide permeation channel, makes Panx1 a primary candidate for participating in the pathophysiology of CNS disorders.

  8. Panx1 was mainly distributed in microcolumn neurons, dysmorphic neurons, balloon cells and reactive astrocytes in cortical lesions from intractable epilepsy patients with focal cortical dysplasia.

  9. ATP release from red blood cells is not mediated by the cAMP-mediated Panx1 pathway.

  10. Panx1 channels are involved in beta-toxin-induced cell death.

Mouse (Murine) Pannexin 1 (PANX1) Interaktionspartner

  1. Panx1 expressed in immune cells is critical for pain-like effects following nerve injury in mice, perhaps via a GPCR (zeige GPBAR1 Antikörper)-mediated activation mechanism, and suggest that inhibition of Panx1 may be useful in treating neuropathic pain.

  2. Auditory brainstem response thresholds in the Gen (zeige GEN1 Antikörper)-Panx1 KO mouse were significantly increased. Distortion product otoacoustic emission and cochlear microphonics were significantly reduced.

  3. These novel findings reveal unique roles for GFAP (zeige GFAP Antikörper)-positive glial and neuronal Panx1 and describe new chronic pain targets for cell-type specific intervention in this often intractable disease.

  4. Panx-1 modulation may be interesting to amplify the clinical effect of cisplatin (DDP (zeige TIMM8A Antikörper)) and reverse the resistance of testicular cancer cells to DDP (zeige TIMM8A Antikörper).

  5. Pannexin1 may play a role in the pathogenesis of liver disease.

  6. Findings indicate a deleterious role for membrane channel Pannexin 1 (Panx1) in response to permanent permanent middle cerebral artery (MCA (zeige RSPH1 Antikörper)) occlusion, that is unique to females.

  7. ATP release from red blood cells is not mediated by the cAMP-mediated Panx1 pathway.

  8. blocking Panx1 and/or Casp4 (zeige CASP4 Antikörper) activities is a beneficial strategy to enhance donor cell engraftment and LG regeneration through the reduction of inflammation.

  9. found a significant increase in waking and a correspondent decrease in slow wave sleep percentages in the Panx1-/- animals.

  10. Diabetic C57BL/6J-Ins2Akita mice were used to evaluate in vivo effects of high glucose on P2R and Panx1

Pannexin 1 (PANX1) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Genbezeichner und Symbole assoziert mit anti-Pannexin 1 (PANX1) Antikörper

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  • UNQ2529 Antikörper
  • zgc:55631 Antikörper

Bezeichner auf Proteinebene für anti-Pannexin 1 (PANX1) Antikörper

pannexin 1 , pannexin-1 , innexin

393890 Danio rerio
466751 Pan troglodytes
697204 Macaca mulatta
772164 Gallus gallus
100014304 Monodelphis domestica
100170473 Xenopus (Silurana) tropicalis
100171730 Pongo abelii
24145 Homo sapiens
607532 Canis lupus familiaris
528169 Bos taurus
55991 Mus musculus
315435 Rattus norvegicus
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