Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) ELISA Kits

Human Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) Interaktionspartner

1. Data suggest positive feedback loops including oligodendrocyte transcription factor 2 (OLIG2): loops of epigenetic regulation.

2. Data show that oligodendrocyte transcription factor 2 (OLIG2) is epigenetically regulated via DNA methylation and expressed in a subset of AML (zeige RUNX1 ELISA Kits) patients.

3. Ectopic expression of phosphomimetic Olig2 is sufficient to block TGF-beta2 (zeige TGFB2 ELISA Kits)-mediated invasion.

4. phosphorylation of the motif itself serves as a template to prime phosphorylation of additional serines and creates a highly charged "acid blob" in the amino terminus of Olig2.

5. Olig2 was expressed in cord blood eosinophils on d 24, when cord blood eosinophils are considered fully differentiated, but no earlier. It was also expressed in human peripheral-blood eosinophils but not neutrophils, monocytes, lymphocytes, or cord blood mast cells. Many genes, including eosinophil surface molecules, were up-regulated along with OLIG2. OLIG2 shRNA or siRNA downregulated SIGLEC-8 (zeige SIGLEC8 ELISA Kits) mRNA and protein.

6. Data indicate that transcription factors Sox10 (zeige SOX10 ELISA Kits) and Olig2 play key roles in oligodendrocytes (OLs) specification.

7. Olig2 expressions were successfully detected in 12 (15.58%) of 77 SVZ type II Glioblastomas (GBs) and 16 (21.3%) of 75 SVZ type III GBs.

8. Olig2 was positive in 5 out of 44 ependymomas (11%) and 50 out of 54 (93%) non-ependymal tumors

9. The present study is the first to verify the associations of SNPs rs762178, rs1059004, and rs9653711 of the OLIG2 gene with OCD in a Chinese Han population. Thus, OLIG2 might serve as a potential target for OCD treatment

10. The results demonstrate that the expression of Olig2 in dental pulp stem cells reduces the expression of stem cell markers and induces the development of oligodendrocyte progenitors.

Zebrafish Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) Interaktionspartner

1. these data raise the possibility that cells expressing olig2 are intermediate targets that help guide facial motor neuron migration.

2. Study detected at least five different classes of olig2-positive cells in the telencephalon of the adult zebrafish.

3. By cooperating with Shh (zeige SHH ELISA Kits), FGF-receptor (zeige FGFR2 ELISA Kits) signalling controls the expression of olig2, a patterning gene essential for the specification of somatic motoneurons and oligodendrocytes.

4. Loss of olig2 function prevents primary motor neuron and oligodendrocyte development, whereas olig2 overexpression promotes formation of excess primary motor neurons and oligodendrocytes.

5. Olig2 is required for repression of iro3 expression in the progenitor domain of ventral spinal cord

6. data indicate that Hedgehog (zeige SHH ELISA Kits) & Wnt (zeige WNT2 ELISA Kits) work in opposition across the dorsoventral axis of the cerebellum to regulate formation of olig2(+) neurons; we propose that Hedgehog (zeige SHH ELISA Kits) limits the range of Wnt (zeige WNT2 ELISA Kits) signaling, which is necessary for olig2(+) neuron development

7. commitment of basal diencephalic DA neurons is regulated by the combined action of the neural protein Olig2 and its downstream neuronal specific effector Sim1

Mouse (Murine) Oligodendrocyte Lineage Transcription Factor 2 (OLIG2) Interaktionspartner

1. Olig2 is down-regulated in oligodendrocyte progenitor cells infected by Theiler's murine encephalomyelitis virus.

2. phosphorylation of the motif itself serves as a template to prime phosphorylation of additional serines and creates a highly charged "acid blob" in the amino terminus of Olig2.

3. OLIG2 modulates growth factor signaling in two distinct populations of glioma stem cells, characterized by expression of either the epidermal growth factor receptor (EGFR (zeige EGFR ELISA Kits)) or platelet-derived growth factor receptor alpha (zeige PDGFRA ELISA Kits).

4. the dynamic interplay between HMGNs and H1 in chromatin epigenetically regulates the expression of OLIG1 (zeige OLIG1 ELISA Kits)&2, thereby affecting oligodendrocyte development and myelination, and mouse behavior.

5. Olig2 was significantly upregulated and transcriptionally targeted the Gpr17 locus

6. Brg1 (zeige SMARCA4 ELISA Kits) represses Olig2 expression and the specification of oligodendrocyte progenitors, but is required for OPC differentiation and oligodendrocyte maturation

7. Data show that oligodendrocyte transcription factor 2 (Olig2) deletion causes platelet-derived growth factor receptor (PDGFR (zeige PDGFRB ELISA Kits)) downregulation and reciprocal epidermal growth factor receptor (EGFR (zeige EGFR ELISA Kits)) upregulation.

8. This study suggests that Olig2 misexpression in neural stem cells elicits neurogenesis defects and neuronal cell death, which may contribute to developmental disorders including Down syndrome

9. OLIG2 is a multifunctional regulator of neural stem cell self-renewal

10. Olig2 expression is localized to the cochleovestibular ganglia from E12.5 through E14.5