anti-Nuclear RNA Export Factor 1 (NXF1) Antikörper

NXF1 is one member of a family of nuclear RNA export factor genes. Zusätzlich bieten wir Ihnen NXF1 Kits (32) und NXF1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NXF1 10482 Q9UBU9
NXF1 53319 Q99JX7
NXF1 59087 O88984
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Top anti-NXF1 Antikörper auf antikoerper-online.de

Showing 10 out of 82 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-NXF1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HepG2 cell lysate NXF1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit Anti-NXF1 Antibody   Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic, nucleus Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-NXF1 Antibody Titration:  1.25ug/ml  Positive Control:  HepG2 cell lysate NXF1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit Anti-NXF1Antibody  Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of NXF1 expression in HeLa (A), A673 (B), K562 (C), Jurkat (D), A431 (E) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded NCIN87 Xenograft , using TAP , antibody at 1:100 dilution. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TAP , antibody at 1:200 dilution. 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert ICC, IF, WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE  diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TAP, antibody at 1:200 dilution. 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Verfügbar
$363.46
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis on HeLa cell lysate using NXF1 Antibody,The lane on the left is treated with the antigen-specific peptide. ABIN6266750 staining HeLa by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody. 100 μL 11 bis 12 Tage
$390.77
Details
Hund Kaninchen Unkonjugiert IHC, IHC (p), WB 100 μL 11 bis 14 Tage
$493.17
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 200 μL 12 bis 14 Tage
$438.90
Details

Weitere Antikörper gegen NXF1 Interaktionspartner

Human Nuclear RNA Export Factor 1 (NXF1) Interaktionspartner

  1. NXF1 is involved in coordinating transcriptional dynamics, 3' end processing, and nuclear export of long 3' UTR transcripts, implicating NXF1 as a nexus of gene regulation.

  2. Gain or loss-of-function experiments revealed NXF1 selectively regulates TLR7-driven IRF5 transcriptional activity, suggesting a new role for NXF1 in the IRF5 signaling pathway.

  3. repeat RNA-sequestration of SRSF1 triggers the NXF1-dependent nuclear export of C9ORF72 transcripts retaining expanded hexanucleotide repeats

  4. small hairpin RNA-mediated down-regulation of TAP or Aly reduced nuclear export of HDAg-L and assembly of HDV virions. Furthermore, a peptide, TAT-HDAg-L(198-210), containing the 10-amino acid TAT peptide and HDAg-L(198-210), inhibited the interaction between HDAg-L and TAP and blocked HDV virion assembly and secretion.

  5. Hepatitis B virus core protein associates with the cellular NXF1-p15 complex via the nuclear export signal motif of hepatitis B virus core protein.Nuclear export of human hepatitis B virus core protein and pregenomic RNA depends on the NXF1-p15 machinery.

  6. Complementary structural, biochemical and cellular techniques indicated that the formation of a symmetric RNA binding platform generated by dimerization of NXF1:NXT1 facilitates the recognition of CTE-RNA and promotes its nuclear export

  7. Gag polyprotein synthesis was decreased by NXF1 knockdown.

  8. a spatial map is produced in living cells of the sites for the interaction of two TREX subunits, Alyref and Chtop, with Nxf1.

  9. TREX is the major complex used to recruit Nxf1 to mRNA in human cells.

  10. the organization of the NXF1 proline-tyrosine nuclear localization signal reveal unexpected redundancy in the nuclear import pathways used by NXF1.

  11. The U2AF65 protein served as an adaptor to link expanded CAG RNA to NXF1 for RNA export.

  12. The crystal structure of the RNA recognition and leucine-rich repeat motifs of TAP bound to one symmetrical half of the CTE RNA is solved.

  13. these data revealed a redox-regulated chaperone function of PDI in delivering antigenic peptides from TAP to MHC-I.

  14. Tpr plays an important role in quality control of mRNA trafficked on the Nxf1 pathway.

  15. These results showed that the interaction between herpes simplex virus type 1 ICP27 and human TAP/NXF1 occurred in living cells upon head-to-tail intramolecular association of ICP27.

  16. Varicella-zoster virus IE4 protein interacts with SR proteins and exports mRNAs through the TAP/NXF1 pathway

  17. Depletion of NXF1 or 5,6-dichloro-1-beta-d-ribofuranosyl-benzimidazole treatment had similar effects, inhibiting the nuclear export of several of the H5N1 influenza virus mRNAs.

  18. Results describe the subcellular localization of ICP27 and its colocalization with cellular RNA export factors Aly/REF and TAP/NXF1.

  19. The structural and mutational data define a novel RNA-binding site on the Tap protein

  20. Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1

Mouse (Murine) Nuclear RNA Export Factor 1 (NXF1) Interaktionspartner

  1. Mutation E610G, quantitatively accounts for the Nxf1 modifier gene activity toward IAP insertion.

  2. Taken together, the results show for the first time that murine leukemia virus requires the Tap/NXF1-mediated export pathway for the expression of its spliced and unspliced RNAs and for full-legth RNA nuclear export.

  3. Disruption of NXF1 expression impaired cytoplasmic accumulations of both spliced and unspliced RNA transcripts of Murine leukemia virus.

  4. Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA toxicity in polyQ diseases.

  5. RNA transport element RTE evolved as a high affinity RBM15 ligand to provide a splicing-independent link to NXF1, thereby ensuring efficient nuclear export and expression of retrotransposon transcripts

  6. FMRP and Nxf2 associate with and destabilize Nxf1 mRNA in neuronal cells.

  7. CAST allele of Nxf1 suppresses IAP-Idelta1 insertions in Ap3d1[mh2J], Atcay[hes], Mgrn1[md] and Usp14[axJ]. Does not suppress the Mitf[mi-bw] LINE nor any of six tested ETn insertion alleles.

  8. The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.

  9. Allelic variation in Nxf1 suppresses RNA processing defects in IAP insertion alleles of Pitpn (vibrator) and Eya1 (branchio-oto-renal syndrome).

NXF1 Antigen-Profil

Protein Überblick

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit NXF1

  • nuclear RNA export factor 1 (nxf1) Antikörper
  • nuclear RNA export factor 1 S homeolog (nxf1.S) Antikörper
  • nuclear RNA export factor 1 (NXF1) Antikörper
  • nuclear RNA export factor 1 (LOC100113601) Antikörper
  • nuclear RNA export factor 1 (Tsp_03999) Antikörper
  • nuclear RNA export factor 1 (Nxf1) Antikörper
  • Nuclear RNA export factor 1 (nxf-1) Antikörper
  • im:7156527 Antikörper
  • Mex67 Antikörper
  • Mex67h Antikörper
  • MGC82224 Antikörper
  • Mvb1 Antikörper
  • NXF1 Antikörper
  • Tap Antikörper
  • wu:fc12d06 Antikörper

Bezeichner auf Proteinebene für NXF1

nuclear RNA export factor 1 , small bristles , Nuclear RNA export factor 1 , nuclear RNA export factor 1-like , mRNA export factor TAP , tip associating protein , tip-associated protein , tip-associating protein , Mex 67 homolog , modifier of vibrator 1 , nuclear RNA export factor 1 homolog , tip associated protein

GENE ID SPEZIES
323865 Danio rerio
432035 Xenopus laevis
451267 Pan troglodytes
734058 Xenopus (Silurana) tropicalis
100049009 Equus caballus
100113601 Nasonia vitripennis
100380454 Salmo salar
100399719 Callithrix jacchus
10904254 Trichinella spiralis
10482 Homo sapiens
483780 Canis lupus familiaris
512136 Bos taurus
53319 Mus musculus
59087 Rattus norvegicus
100347351 Oryctolagus cuniculus
100628213 Sus scrofa
769691 Gallus gallus
101115327 Ovis aries
100728879 Cavia porcellus
191736 Caenorhabditis elegans
Ausgewählte Anbieter für anti-NXF1 (NXF1) Antikörper
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