anti-Non-POU Domain Containing, Octamer-Binding (NONO) Antikörper

NONO encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. Zusätzlich bieten wir Ihnen NONO Proteine (8) und NONO Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
NONO 4841 Q15233
NONO 317259 Q5FVM4
NONO 53610 Q99K48
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Top anti-NONO Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, WB <b>WB Suggested Anti-NONO Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Hund Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Rind (Kuh) Kaninchen Unkonjugiert IF, IHC, WB <b>WB Suggested Anti-NONO Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Hund Maus Unkonjugiert IF, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IHC (p), WB NONO Antibody (N-term) (ABIN657703) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the NONO antibody detected the NONO protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), IP, PLA, WB Detection of Human NONO by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 1/4 of IP reaction loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-NONO antibody ABIN151100 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. NONO was also immunoprecipitated using anti-NONO antibody ABIN151095 at 3 mcg/mg lysate. Detection: Chemiluminescence with exposure times of 10 seconds (A and B). Western Blot: NONO Antibody [ABIN151100] - Whole cell lysate NIH3T3, TCMK-1, 4T1, CT26.WT, and rat C6 cells. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Hund Maus Unkonjugiert BI, WB Western blot analysis of p54 [nrb] on a Jurkat lysate. Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10000 dilution of the p54 [nrb] antibody. Immunofluorescent staining of A549 (ATCC CCL-185) cells. Cells were seeded in a 96 well imaging plate at ~ 10 000 cells per well. After overnight incubation, cells were stained using the alcohol perm protocol and the anti-p54 [nrb] antibody. The second step reagent was FITC goat anti mouse Ig. The image was taken on a BD Pathway™ 855 Bioimager using a 20x objective. This antibody also stained HeLa (ATCC CCL-2) and U-2 OS (ATCC HTB-96) cells using both the Triton™ X-100 and alcohol perm protocols. 150 μg Anmelden zum Anzeigen 6 bis 8 Tage
$305.54
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185629 (0.1µg/ml) staining of mouse brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image p54/nrb antibody detects p54/nrb protein at nucleus in mouse brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse brain. p54/nrb antibody , diluted at 1:500. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$288.00
Details

NONO Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-NONO Antikörper

  1. Dog (Canine) Monoclonal NONO Primary Antibody für BI, WB - ABIN968450 : Basu, Dong, Krainer, Howe: The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO. in Molecular and cellular biology 1997 (PubMed)
    Show all 3 Pubmed References

  2. Dog (Canine) Monoclonal NONO Primary Antibody für BI, WB - ABIN968451 : Dong, Horowitz, Kobayashi, Krainer: Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6. in Nucleic acids research 1993 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal NONO Primary Antibody für IHC, IHC (p) - ABIN151100 : Zhang, Zhang, Shen, Burks, Zhang, Wang, LeMaire, Yoshimura, Aoki, Coselli, Wang: TNF-alpha suppresses prolyl-4-hydroxylase alpha1 expression via the ASK1-JNK-NonO pathway. in Arteriosclerosis, thrombosis, and vascular biology 2007 (PubMed)
    Show all 3 Pubmed References

  4. Cow (Bovine) Polyclonal NONO Primary Antibody für IF, WB - ABIN2779027 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal NONO Primary Antibody für IHC (p), IHC - ABIN251463 : Brown, Ripperger, Kadener, Fleury-Olela, Vilbois, Rosbash, Schibler: PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. in Science (New York, N.Y.) 2005 (PubMed)

  6. Cow (Bovine) Polyclonal NONO Primary Antibody für IF, IHC - ABIN2779028 : Kimura, Wakamatsu, Suzuki, Ota, Nishikawa, Yamashita, Yamamoto, Sekine, Tsuritani, Wakaguri, Ishii, Sugiyama, Saito, Isono, Irie, Kushida, Yoneyama, Otsuka, Kanda, Yokoi, Kondo, Wagatsuma, Murakawa et al.: Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ... in Genome research 2006 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen NONO Interaktionspartner

Human Non-POU Domain Containing, Octamer-Binding (NONO) Interaktionspartner

  1. Findings reveal a new mechanism whereby HUR (zeige ELAVL1 Antikörper) protects NONO from mir320-mediated degradation upon UVC exposure and identify a new component within the complex network of players underlying the DNA damage response adding mir320a to the list of p53 (zeige TP53 Antikörper)-regulated targets upon genotoxic stress.

  2. GAPLINC has a role in promoting colorectal cancer invasion via binding to PSF/NONO and partly by stimulating the expression of SNAI2

  3. Here, it is reported that l-proline stabilizes purified NONO homodimers, enabling good-quality solution small-angle X-ray structure determination and crystallization. NONO crystallized in the apparent space group P21 (zeige CDKN1A Antikörper) with a unique axis (b) of 408.9 A and with evidence of twinning, as indicated by the cumulative intensity distribution L statistic, suggesting the possibility of space group P1.

  4. Mechanistic dissection reveals that NEAT1 broadly interacts with the NONO-PSF (zeige IGFBP7 Antikörper) heterodimer as well as many other RNA-binding proteins and that multiple RNA segments in NEAT1, including a 'pseudo pri-miRNA' near its 3' end, help attract the Drosha (zeige DROSHA Antikörper)-DGCR8 (zeige DGCR8 Antikörper) Microprocessor.

  5. The SFPQ (zeige SFPQ Antikörper)*NONO complex contains an RNA binding domain, and prior work has demonstrated diverse roles in RNA metabolism. It is thus plausible that the additional repair function of NONO, revealed in cell-based assays, could involve RNA interaction.

  6. NEAT1-associated paraspeckle proteins P54nrb and PSF (zeige IGFBP7 Antikörper) have been reported as positive regulators of c-Myc (zeige MYC Antikörper) translation through interaction with c-Myc (zeige MYC Antikörper) IRES

  7. Exome analysis identified a novel de novo splice-site variant c.1171+1G>T in exon 11 of NONO gene in a patient with intellectual disability and non-compaction cardiomyopathy.

  8. Case Report: melanotic PEComa of the sinonasal mucosa with NONO-TFE3 (zeige TFE3 Antikörper) fusion.

  9. High expression of P54 (zeige DDX6 Antikörper) is associated with breast cancer.

  10. The present study indicates that p54nrb is a powerful molecule involved in the regulation of cell motility and promotes the migration and invasion of THP1 (zeige GLI2 Antikörper) cells, and it is more likely to be involved in the release of inflammatory mediators and the motility of inflammatory cells.

Mouse (Murine) Non-POU Domain Containing, Octamer-Binding (NONO) Interaktionspartner

  1. These findings argue that Nono collaborates with Erk (zeige EPHB2 Antikörper) signaling to regulate the integrity of bivalent domains and Mouse embryonic stem cell pluripotency.

  2. NONO deficiency significantly compromises the response to ionizing radiation-induced DNA damage in the testes, consistent with cell type-specific loss of DSB repair capacity. The results provide evidence that this RNA binding protein significantly contributes to the DNA damage response in vivo.

  3. Data indicate involvement of non-POU domain-containing octamer-binding protein (NONO)/paraspeckle protein component 1 (PSPC1 (zeige PSPC1 Antikörper))-aldehyde dehydrogenase 1 (NONO/PSPC1 (zeige PSPC1 Antikörper)-ALDH1A1 (zeige ALDH1A1 Antikörper)) in the modulation of Sertoli cells (SCs (zeige TWIST1 Antikörper)) response to mono-(2-ethylhexyl) phthalate (MEHP) challenge.

  4. This study provides an improved understanding of the molecular basis (structure and dynamics) that governs the binding of the p54(nrb)/NonO RRM1 (zeige RRM1 Antikörper) to one of its target RNAs.

  5. mechanisms have therapeutic implications for reducing beta-cell proliferation in insulinomas by inhibiting phospho-HLXB9 or its interaction with Nono and modulating the expression of its direct (Cblb) or indirect (c-Met) targets

  6. Cytoplasmic granule containing HERMES (zeige CD44 Antikörper), NonO, PSF (zeige IL-3 Antikörper), and G3BP1 (zeige G3BP1 Antikörper) is a neuronal RNA-protein granule that is transported in neurites during retinal differentiation.

  7. Quantitative proteomics reveals dynamic interaction of JNK (zeige MAPK8 Antikörper) with RNA transport granule proteins Sfpq (zeige SFPQ Antikörper) and Nono during neuronal differentiation

  8. We analyzed the expression of sperm-specific Akap3 (zeige AKAP3 Antikörper) and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.

  9. NONO genetic insufficiency led to upregulation of PSPC1 (zeige PSPC1 Antikörper), which replaced NONO in a stable complex with SFPQ (zeige SFPQ Antikörper).

  10. Dsta indicate that NONO bound to p16-Ink4A cell cycle checkpoint gene and potentiated its circadian activation in a PER protein-dependent fashion.

NONO Antigen-Profil

Protein Überblick

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.

Genbezeichner und Symbole assoziert mit NONO

  • non-POU domain containing octamer binding (NONO) Antikörper
  • non-POU domain containing, octamer-binding (NONO) Antikörper
  • non-POU domain containing, octamer-binding (Nono) Antikörper
  • non-POU domain containing, octamer binding L homeolog (nono.L) Antikörper
  • non-POU-domain-containing, octamer binding protein (Nono) Antikörper
  • AA407051 Antikörper
  • AV149256 Antikörper
  • nmt55 Antikörper
  • nonA Antikörper
  • nrb54 Antikörper
  • P54 Antikörper
  • p54nrb Antikörper
  • xp54nrb Antikörper

Bezeichner auf Proteinebene für NONO

54 kDa nuclear RNA- and DNA-binding protein , 55 kDa nuclear protein , DNA-binding p52/p100 complex, 52 kDa subunit , non-POU domain-containing octamer (ATGCAAAT) binding protein , non-POU domain-containing octamer-binding protein , p54(nrb) , non-POU-domain-containing, octamer-binding protein , 54 kD nuclear RNA-binding protein

GENE ID SPEZIES
4841 Homo sapiens
428701 Gallus gallus
612773 Canis lupus familiaris
615175 Bos taurus
317259 Rattus norvegicus
380427 Xenopus laevis
53610 Mus musculus
Ausgewählte Anbieter für anti-NONO (NONO) Antikörper
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