anti-Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Antikörper

M6PR encodes a member of the P-type lectin family.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human M6PR M6PR 4074 P20645
Anti-Maus M6PR M6PR 17113 P24668
Anti-Ratte M6PR M6PR 312689 Q6AY20
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Top anti-M6PR Antikörper auf antikoerper-online.de

Showing 10 out of 71 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-M6PR Antibody Titration:  5.0ug/ml  Positive Control:  Jurkat cell lysate Human, Mouse 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert FACS, IF, WB M6PR Antibody (C-term) (ABIN650726) western blot analysis in A549 cell line lysates (35 µg/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow). M6PR Antibody (C-term) (ABIN650726) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p) 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of M6PR Antibody (N-term)(ABIN389291) in mouse brain tissue lysates (35 µg/lane). M6PR (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term) (ABIN389291), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, WB IHC-P on paraffin sections of human liver.HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT  Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. IHC-P on paraffin sections of human liver.HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module.Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm.Detection was done using Novolink HRP polymer from Leica following manufacturers instructions.Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer).Sections were counterstained with Harris Hematoxylin. 100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Hund Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of Mouse kidney cell line, using M6PR antibody. Immunohistochemistry of paraffin-embedded human liver injury using M6PR antibody at dilution of 1:100 (x40 lens). 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Fledermaus Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (33.48 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details

Am meisten referenzierte anti-M6PR Antikörper

  1. Cow (Bovine) Polyclonal M6PR Primary Antibody für ELISA - ABIN408673 : Frei, Jeon, Kilcher, Moest, Henning, Jost, Plückthun, Mercer, Aebersold, Carreira, Wollscheid: Direct identification of ligand-receptor interactions on living cells and tissues. in Nature biotechnology 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal M6PR Primary Antibody für ELISA, WB - ABIN561704 : Steffan, Williams, Welbourne, Cardelli: HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers. in Journal of cell science 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen M6PR Interaktionspartner

Human Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaktionspartner

  1. In light of existing report suggesting critical role of Nef-GCC185 (zeige GCC2 Antikörper) interaction reveals valuable mechanistic insights affecting specific protein transport pathway in docking of late endosome derived Rab9 (zeige RAB9A Antikörper) bearing transport vesicle at TGN (zeige TG Antikörper) elucidating role of Nef during viral pathogenesis.

  2. Results suggest that Rab (zeige HRB Antikörper) protein Rab29 (zeige RAB7L1 Antikörper) is essential for the integrity of the trans-Golgi network (TGN (zeige TG Antikörper)) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR).

  3. These data indicate that clathrin is required for the function of AP-1 (zeige FOSB Antikörper)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  4. Sortilin (zeige SORT1 Antikörper) is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR (zeige IGF2R Antikörper) is able to internalize circulating alpha-Gal A.

  5. Mannose receptor (MR) engagement by mesothelin (zeige MSLN Antikörper) GPI (zeige GNPDA1 Antikörper) anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody

  6. sorting of the CD-MPR in late endosomes requires a distinct di-aromatic motif with only limited possibilities for variations

  7. We conclude that the CI-MPR (zeige IGF2R Antikörper) participates in lysosomal and granular targeting of serglycin (zeige SRGN Antikörper) and basic proteins such as lysozyme (zeige LYZ Antikörper) associated with the proteoglycan (zeige Vcan Antikörper) in hematopoietic cells.

  8. sortilin (zeige SORT1 Antikörper) and mannose-6-phosphate receptors recycle to the TGN (zeige TG Antikörper) in SNX1 (zeige SNX1 Antikörper)-dependent carriers, which we named endosome-to-TGN (zeige TG Antikörper) transport carriers

  9. Missorting of cathepsin D (zeige CTSD Antikörper) in GARP (zeige CNGB1 Antikörper)-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.

  10. Data demonstrate that Rab31 (zeige RAB31 Antikörper) is required for transport of mannose 6-phosphate receptors from the trans-Golgi network to endosomes and for the Golgi/TGN (zeige TG Antikörper) organization.

Mouse (Murine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaktionspartner

  1. Finally, Chlamydia trachomatis infection interferes with the SNX5 (zeige SNX5 Antikörper):cation-independent mannose-6-phosphate receptor (zeige IGF2R Antikörper) interaction, suggesting that Chlamydia IncE and cation-independent mannose-6-phosphate receptor (zeige IGF2R Antikörper) are dependent on the same binding surface on SNX5 (zeige SNX5 Antikörper).

  2. We conclude that M6PR is an important receptor used by HIV-1 to cross the blood-brain barrier.

  3. Mannose 6-phosphate receptor has a role in acid sphingomyelinase (zeige SMPD1 Antikörper) deficiency

  4. in hepatocytes of MPR (zeige PAQR7 Antikörper)-deficient neonatal mice lysosomal storage occurs when both MPRs are lacking, whereas deficiency of CI-MPR (zeige IGF2R Antikörper) only has no effect on the ultrastructure of the lysosomal system.

  5. Data characterize the retrograde transport of mannose 6-phosphate receptor MPR46 from endosomes to the trans-Golgi network by an in vitro transport assay using mouse fibroblast cell lines.

  6. there is not a an Mpr300- or Mpr46-dependent pathway of granzyme-mediated killing in internalization of monomeric and complexed granzyme B

  7. These results indicate that beta-glucuronidase (zeige GUSB Antikörper) transport into brain parenchyma in early postnatal life is mediated by the mannose 6-phosphate/insulin-like growth factor II receptor (zeige IGF2R Antikörper).

  8. Mpr46 is dispensable on target cells for lysis and apoptosis mediated by alloreactive cytotoxic T lymphocytes.

  9. The murine 46-kDa mannose 6-phosphate receptor has the capacity to deliver its cargo proteins to lysosomes even in the absence of endosomal acidification.

  10. epinephrine restores the M6P receptor-mediated functional transport of (131)I-P-beta-glucuronidase (zeige GUSB Antikörper) across the blood brain barrier in adults to levels seen in the neonate

Cow (Bovine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaktionspartner

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

  2. Expression and binding properties of mannose-6-phosphate receptors CD-MPR and CI-MPR (zeige IGF2R Antikörper) differ during perinatal development in rat liver.

Zebrafish Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaktionspartner

  1. Analysis of full-length sequences for MPR 46 from zebrafish (Danio rerio) and its functional analysis.

Rhesus Monkey Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) Interaktionspartner

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

M6PR Antigen-Profil

Protein Überblick

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Genbezeichner und Symbole assoziert mit M6PR

  • mannose-6-phosphate receptor, cation dependent (M6PR) Antikörper
  • mannose-6-phosphate receptor, cation dependent (M6pr) Antikörper
  • mannose-6-phosphate receptor (cation dependent) L homeolog (m6pr.L) Antikörper
  • mannose-6-phosphate receptor (cation dependent) (m6pr) Antikörper
  • mannose-6-phosphate receptor (cation dependent) S homeolog (m6pr.S) Antikörper
  • mannose-6-phosphate receptor (cation dependent) (Ethha_1678) Antikörper
  • Cation-dependent mannose-6-phosphate receptor (mprd) Antikörper
  • CD-MPR Antikörper
  • CDMPR Antikörper
  • M6PR Antikörper
  • MGC68896 Antikörper
  • MGC89423 Antikörper
  • MGC130765 Antikörper
  • MPR-46 Antikörper
  • MPR 46 Antikörper
  • Mpr46 Antikörper
  • mprd Antikörper
  • SMPR Antikörper
  • wu:fj81h11 Antikörper
  • zgc:77757 Antikörper

Bezeichner auf Proteinebene für M6PR

46-kDa mannose 6-phosphate receptor , CD Man-6-P receptor , Mr 46,000 Man6PR , cation-dependent mannose-6-phosphate receptor , small mannose 6-phosphate receptor , 46 kDa mannose 6-phosphate receptor , MPR 46 , CD-MPR , mannose-6-phosphate receptor (cation dependent) , Mannose 6-Phosphate Receptor , Cation-dependent mannose-6-phosphate receptor , insulin-like growth factor 2 receptor

GENE ID SPEZIES
4074 Homo sapiens
17113 Mus musculus
281291 Bos taurus
312689 Rattus norvegicus
380564 Xenopus laevis
396044 Gallus gallus
406486 Danio rerio
477700 Canis lupus familiaris
493477 Xenopus (Silurana) tropicalis
496207 Xenopus laevis
716696 Macaca mulatta
736013 Pan troglodytes
10092655 Ethanoligenens harbinense YUAN-3
100194796 Salmo salar
100726206 Cavia porcellus
100154117 Sus scrofa
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