M6PR Antikörper (N-Term)

Produktnummer ABIN2781302

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch M6PR in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Pferd.

Kurzübersicht für M6PR Antikörper (N-Term) (ABIN2781302)

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser M6PR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-M6PR Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: M6PR Antibody - N-terminal region

Sequenz: RLKPLFNKSF ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against M6PR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human M6PR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8104832

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Andere Bezeichnung: M6PR

Hintergrund:

Background Information: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.

Gene Name: Mannose-6-phosphate receptor (cation dependent)

Alternative Symbols: SMPR, MPR46, CD-MPR, MPR 46, MPR-46, CD-M6PR

Protein Name: Cation-dependent mannose-6-phosphate receptor

Molekulargewicht: 28kDa

Gen-ID: 4074

NCBI Accession: NP_002346

UniProt: P20645