M6PR Antikörper (N-Term)

Produktnummer ABIN357957

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-M6PR Antikörper (ABIN357957) detektiert spezifisch M6PR in IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für M6PR Antikörper (N-Term) (ABIN357957)

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser M6PR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-M6PR Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects M6PR (N-term).

Aufreinigung: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human M6PR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Immunohistochemistry: 1/10-1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-M6PR Antikörper (ABIN357957)

Ohka, Tan, Ishiyama, Ogasawara, Hanasaka, Ishida, Hagiwara, Liu, Chong, Hanaki, Schiavo: "The uncoating of EV71 in mature late endosomes requires CD-M6PR." in: Biology open, Vol. 11, Issue 9, (2022) (PubMed).

Details zu M6PR

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Andere Bezeichnung: M6PR

Hintergrund: M6PR is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.Synonyms: 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, CD-MPR, Cation-dependent mannose-6-phosphate receptor, MPR46, MPRD

Molekulargewicht: 30993 Da

Gen-ID: 4074, 9606

UniProt: P20645