Keratin 16 Proteine (KRT16)

The protein encoded by KRT16 is a member of the keratin gene family. Zusätzlich bieten wir Ihnen Keratin 16 Antikörper (150) und Keratin 16 Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
KRT16 3868 P08779
KRT16 16666 Q9Z2K1
Ratte KRT16 KRT16 303530  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 10 bis 12 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage

KRT16 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
Mouse (Murine)

Weitere Proteine zu Keratin 16 (KRT16) Interaktionspartnern

Human Keratin 16 (KRT16) Interaktionspartner

  1. results suggest a conditional regulation of KRT16 gene by ATF4 that may be inhibited in normal cells, but engaged during cancer progression. Potential roles of KRT16, FAM129A and HKDC1 genes upregulation in adaptive stress responses and pathologies are discussed

  2. inflammatory cytokines promoted Nrf2 (zeige GABPA Proteine) nuclear translocation in psoriatic epidermis, which led to elevated expression of K6, K16, and K17 (zeige KRT17 Proteine), thus promoting keratinocyte proliferation and contributing to the pathogenesis of psoriasis.

  3. The wider spectrum of KRT16 mutations suggests that changes in codons 125, 127, and 132 are most commonly responsible for PC-1 (zeige PCSK1 Proteine) and that proline substitution mutations at codons 127 or 128 may produce more severe disease

  4. analysis of a new p.Leu421Pro (c.1262T>C) mutation in the highly conserved helix termination motif of K16 in a large Spanish family that may have a role in pachyonychia congenita

  5. Keratin 16 regulates innate immunity in response to epidermal barrier breach.

  6. Data established a seven-gene (AR, ESR2 (zeige ESR2 Proteine), GATA3 (zeige GATA3 Proteine), GBX2 (zeige GBX2 Proteine), KRT16, MMP28 (zeige MMP28 Proteine) and WNT11 (zeige WNT11 Proteine)) prognostic signature to define a subset of triple-negative breast cancer (TNBC).

  7. Genotype-phenotype correlations among PC patients with codon-125 mutation in KRT16 were established, while the phenotypes caused by the IVS8-2A>C mutation in KRT6A (zeige KRT6A Proteine) need further studies to confirm the rare feature of fissured tongue

  8. We found that the KRT16 mutation carriers developed plantar keratoderma at a similar age to KRT6A (zeige KRT6A Proteine) carriers wheras KRT6B (zeige KRT6B Proteine) and KRT17 (zeige KRT17 Proteine) carriers were significantly more likely to report later onset.

  9. Phenotypic differences exist between KRT6A (zeige KRT6A Proteine) and KRT16 mutations support adoption of a new classification system.

  10. Patients with p.Asn125Asp and p.Arg127Pro mutations in KRT16 exhibited more severe disease than patients carrying p.Asn125Ser and p.Arg127Cys mutations in terms of age of onset of symptoms, extent of nail (zeige CD244 Proteine) involvement, and impact on daily quality of life.

Mouse (Murine) Keratin 16 (KRT16) Interaktionspartner

  1. we show that the loss of Krt16 function in mice causes the development of prominent calluses on the plantar side of front and hind paws, which significantly compromise mobility.

  2. Keratin 6 and keratin 16 may play a role in wrinkle formation.

Keratin 16 (KRT16) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Genbezeichner und Symbole assoziert mit Keratin 16 Proteine (KRT16)

  • keratin 17 (KRT17)
  • keratin 16 (KRT16)
  • keratin 16 (Krt16)
  • keratin, type I cytoskeletal 16 (KRT16)
  • keratin 16, type I S homeolog (krt16.S)
  • AI324768 Protein
  • CK16 Protein
  • FNEPPK Protein
  • K1CP Protein
  • K16 Protein
  • Ka16 Protein
  • Krt1-16 Protein
  • krt16 Protein
  • KRT16A Protein
  • KRT17 Protein
  • NEPPK Protein

Bezeichner auf Proteinebene für Keratin 16 Proteine (KRT16)

keratin 17 , keratin 16 , Keratin, type I cytoskeletal 17 , CK-16 , cytokeratin 16 , cytokeratin-16 , focal non-epidermolytic palmoplantar keratoderma , keratin, type I cytoskeletal 16 , keratin-16 , keratin complex 1, acidic, gene 16 , keratin intermediate filament 16a , keratin intermediate filament 16b , keratin 14 , keratin 16 (focal non-epidermolytic palmoplantar keratoderma) , type I keratin KA16

468261 Pan troglodytes
3868 Homo sapiens
16666 Mus musculus
490978 Canis lupus familiaris
100138169 Bos taurus
303530 Rattus norvegicus
446743 Xenopus laevis
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