anti-KIAA1530 (KIAA1530) Antikörper

The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. Zusätzlich bieten wir Ihnen KIAA1530 Proteine (3) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KIAA1530 57654 Q2YD98
Anti-Maus KIAA1530 KIAA1530 71101 Q9D479
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Top anti-KIAA1530 Antikörper auf antikoerper-online.de

Showing 4 out of 6 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using UVSSA antibody [N1N2], N-term , at 1:200 dilution. WB Image Sample(30μg whole cell lysate) A: 293T B: A431 , C: H1299 D: HeLa S3 , E: Hep G2 , F: MOLT4 , G: Raji , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 bis 4 Tage
$466.18
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Human Maus Unkonjugiert WB Western Blot analysis of KIAA1530 expression in transfected 293T cell line by KIAA1530 MaxPab polyclonal antibody.Lane 1: KIAA1530 transfected lysate(28.6 KDa).Lane 2: Non-transfected lysate. 50 μg 11 bis 12 Tage
$440.00
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Human Kaninchen Unkonjugiert WB   100 μL 11 bis 14 Tage
$551.83
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Human Kaninchen Unkonjugiert ELISA, WB   100 μg 13 bis 16 Tage
$430.77
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Am meisten referenzierte anti-KIAA1530 Antikörper

  1. Human Polyclonal KIAA1530 Primary Antibody für ICC, IF - ABIN442562 : Nakazawa, Sasaki, Mitsutake, Matsuse, Shimada, Nardo, Takahashi, Ohyama, Ito, Mishima, Nomura, Kinoshita, Ono, Takenaka, Masuyama, Kudo, Slor, Utani, Tateishi, Yamashita, Stefanini, Lehmann, Yoshiura et al.: Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. ... in Nature genetics 2012 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen KIAA1530 Interaktionspartner

Human KIAA1530 Interaktionspartner

  1. UVSSA is mono-ubiquitinated in vitro. Lys(414) is the target of ubiquitination. Lys(414) was also modified by poly-ubiquitin chains in vivo. The substitution of Lys(414) by Arg of UVSSA inhibited its degradation and thereby suppressed the deficiency in transcription-coupled nucleotide excision repair.

  2. Data suggest that a common TFIIH subunit p62 recruitment mechanism is shared by UV-stimulated scaffold protein A (UVSSA) in transcription-coupled repair (TCR) and xeroderma pigmentosum, complementation group C protein (XPC) in global genome repair (GGR).

  3. stabilization of UVSSA by interaction with USP7 is essential for Transcription-coupled Nucleotide Excision Repair

  4. UVSSA together with USP7 is implicated in regulating transcription-coupled DNA repair.[review]

  5. Human UVSSA protein is required for the ubiquitination of RNA polymerase and DNA repair after light-induced DNA damage [review].

  6. KIAA1530 is an important player in TCR but also lead to a better understanding of the molecular mechanism underlying UV(s)S syndrome.

  7. Mutations in the UVSSA gene is associated with UV-sensitive syndrome.

  8. Mutations in UVSSA cause UV-sensitive syndrome and recruits USP7 to regulate transcription-coupled repair.

  9. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.

KIAA1530 Antigen-Profil

Protein Überblick

The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3.

Genbezeichner und Symbole assoziert mit anti-KIAA1530 (KIAA1530) Antikörper

  • UV stimulated scaffold protein A (UVSSA) Antikörper
  • UV stimulated scaffold protein A (uvssa) Antikörper
  • UV stimulated scaffold protein A (Uvssa) Antikörper
  • 4933407H18Rik Antikörper
  • D330017J19Rik Antikörper
  • Kiaa1530 Antikörper
  • mKIAA1530 Antikörper
  • UVSS3 Antikörper

Bezeichner auf Proteinebene für anti-KIAA1530 (KIAA1530) Antikörper

UV-stimulated scaffold protein A

GENE ID SPEZIES
57654 Homo sapiens
100135095 Xenopus (Silurana) tropicalis
71101 Mus musculus
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