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UVSSA/KIAA1530 Antikörper (AA 143-206) (FITC)

UVSSA Reaktivität: Human Wirt: Kaninchen Polyclonal FITC
Produktnummer ABIN7175184
  • Target Alle UVSSA/KIAA1530 (UVSSA) Antikörper anzeigen
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    AA 143-206
    Reaktivität
    Human
    Wirt
    • 5
    • 2
    Kaninchen
    Klonalität
    • 6
    • 1
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    Dieser UVSSA/KIAA1530 Antikörper ist konjugiert mit FITC
    Applikation
    Bitte anfragen
    Kreuzreaktivität
    Human
    Aufreinigung
    >95%, Protein G purified
    Immunogen
    Recombinant Human UV-stimulated scaffold protein A protein (143-206AA)
    Isotyp
    IgG
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
    Andere Bezeichnung
    UVSSA (UVSSA Produkte)
    Synonyme
    KIAA1530 antikoerper, UVSS3 antikoerper, kiaa1530 antikoerper, 4933407H18Rik antikoerper, D330017J19Rik antikoerper, Kiaa1530 antikoerper, mKIAA1530 antikoerper, UV stimulated scaffold protein A antikoerper, UVSSA antikoerper, uvssa antikoerper, Uvssa antikoerper
    Hintergrund

    Background: Factor involved in transcription-coupled nucleotide excision repair (TC-NER) in response to UV damage. TC-NER allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Acts by promoting stabilization of ERCC6 by recruiting deubiquitinating enzyme USP7 to TC-NER complexes, preventing UV-induced degradation of ERCC6 by the proteasome. Interacts with the elongating form of RNA polymerase II (RNA pol IIo) and facilitates its ubiquitination at UV damage sites, leading to promote RNA pol IIo backtracking to allow access to the nucleotide excision repair machinery. Not involved in processing oxidative damage.

    Aliases: hypothetical protein LOC57654 antibody, K1530_HUMAN antibody, KIAA1530 antibody, Uncharacterized protein KIAA1530 antibody, UV stimulated scaffold protein A antibody, UVSS3 antibody, UVSSA antibody

    UniProt
    Q2YD98
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