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The protein encoded by IL23 is a member of the interleukin 1 cytokine family. Zusätzlich bieten wir Ihnen Interleukin 23 Kits (89) und Interleukin 23 Antikörper (74) und viele weitere Produktgruppen zu diesem Protein an.
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The serum levels of IL-37, which were correlated with antibody production and the serum levels of total IL-18 (zeige IL18 Proteine) and IL-18BP (zeige IL18BP Proteine), were elevated in the patients with primary Sjogren's syndrome.
this study shows that human IL-37 inhibited LPS (zeige IRF6 Proteine)-induced mouse osteoclast formation and bone resorption via inhibition of LPS (zeige IRF6 Proteine)-induced osteoclast related cytokines
serum IL-37 and its mRNA expression is increased in Ankylosing spondylitis (AS) patients with special consideration in patient with Osteoporosis and correlates with disease activity and BMD (zeige BEST1 Proteine) which indicate that IL-37 may provide a novel research target for pathogenesis and therapy of AS.
IL-27 (zeige IL27 Proteine) and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. stercoralis infections, which suggest the importance of IL-27 (zeige IL27 Proteine) and IL-37 in immune modulation in a chronic helminth infection.
IL-37 regulates autophagy in SMMC-7721 and Huh-7 cells via inhibition of the PI3K (zeige PIK3CA Proteine)/AKT (zeige AKT1 Proteine)/mTOR (zeige FRAP1 Proteine) signaling pathway.
IL37 itself reduced IL1beta (zeige IL1B Proteine), IL6 (zeige IL6 Proteine) and IL8 (zeige IL8 Proteine) production in osteoarthritis chondrocytes, indicating that IL37 is able to induce a counter-regulatory anti-inflammatory feedback loop in chondrocytes. In addition, IL37 dampens catabolic enzyme expression.
this study shows that IL-37 could decrease both NF-kappaB (zeige NFKB1 Proteine) and ICAM-1 (zeige ICAM1 Proteine) expression upon TLR2 activation in human coronary artery endothelial cells, and that this effect may be due to its inhibition on NF-kappaB (zeige NFKB1 Proteine)
Results show that elevated plasma IL-37 level and its associations with anti-Sm, anti-RNP (zeige RNPC3 Proteine) and C3 in systemic lupus erythematosus patients suggest that IL-37 may be implicated in this disease.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
, IL-1 zeta
, IL-1F7b (IL-1H4, IL-1H, IL-1RP1)
, IL-1X protein
, IL1F7 (canonical product IL-1F7b)
, interleukin 1 family member 7
, interleukin 1, zeta
, interleukin-1 homolog 4
, interleukin-1 superfamily z
, interleukin-1-related protein