anti-GSTa2 Antikörper

Protein Überblick

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Genbezeichner und Symbole assoziert mit GSTa2

• glutathione S-transferase alpha 2 (GSTA2) Antikörper
• glutathione S-transferase alpha 2 (Gsta2) Antikörper
• glutathione S-transferase (GSTA2) Antikörper
• glutathione S-transferase, alpha 2 (Yc2) (Gsta2) Antikörper

• GST2 Antikörper
• Gst2-2 Antikörper
• Gsta1 Antikörper
• GSTA2-2 Antikörper
• Gstc-2 Antikörper
• Alle Synonyme
• Gstc2 Antikörper
• GTA2 Antikörper
• GTH2 Antikörper

Bezeichner auf Proteinebene für GSTa2

GST class-alpha member 1 , GST class-alpha member 2 , glutathione S-transferase A1 , glutathione S-transferase A2 , glutathione S-transferase alpha 1 , glutathione S-transferase alpha-1 , glutathione S-transferase alpha-2 , GST HA subunit 2 , GST-gamma , S-(hydroxyalkyl)glutathione lyase A2 , glutathione S-alkyltransferase A2 , glutathione S-aralkyltransferase A2 , glutathione S-aryltransferase A2 , liver GST2 , GST 1-1 , GST 1a-1a , GST A1-1 , GST B , GST Ya1 , Glutathione-S-transferase alpha type (Yc?) , glutathione S-transferase Ya subunit , glutathione S-transferase Ya-1 , glutathione-S-transferase, alpha type2 , ligandin , glutathione S-transferase alpha class A2 , glutathione S-transferase GT41A