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The protein encoded by GCDH belongs to the acyl-CoA dehydrogenase family. Zusätzlich bieten wir Ihnen Glutaryl-CoA Dehydrogenase Antikörper (66) und Glutaryl-CoA Dehydrogenase Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.
glutaryl-CoA dehydrogenase, mitochondrial
, glutaryl-Coenzyme A dehydrogenase