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Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Zusätzlich bieten wir Ihnen GFRA2 Proteine (17) und GFRA2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
GDNF family receptor alpha-2
, GDNF receptor beta
, GFR-alpha 2
, PI-linked cell-surface accessory protein
, RET ligand 2
, TGF-beta-related neurotrophic factor receptor 2
, TRN receptor, GPI-anchored
, glial cell line derived neurotrophic factor receptor, beta
, neurturin receptor alpha
, GDNF receptor alpha-2
, GFR alpha 2
, GFR alpha-2
, CDC42 binding protein kinase alpha (DMPK-like)
, glial cell line derived neurotrophic factor family receptor alpha 2
, tyrosine kinase receptor ligand 2
, GDNF family receptor alpha 2
, GDNF family receptor alpha-2-like