anti-GDNF Family Receptor alpha 2 (GFRA2) Antikörper

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Zusätzlich bieten wir Ihnen GFRA2 Proteine (17) und GFRA2 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GFRA2 2675 O00451
GFRA2 25136  
GFRA2 14586  
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Top anti-GFRA2 Antikörper auf antikoerper-online.de

Showing 10 out of 74 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GFRA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human brain Host: Rabbit <br /> Target Name: GFRA2 <br /> Sample Tissue: Human Adult Placenta <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$466.62
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-GDNF-Receptor-alpha-2 Polyclonal Antibody, Unconjugated (ABIN724235) 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-GDNF-Receptor-alpha-2 Polyclonal Antibody, Unconjugated (ABIN724235) 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, PE conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Unkonjugiert ICC, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert EIA, IF, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$375.38
Details
Human Kaninchen Unkonjugiert WB GFRA2 Antibody (C-term) (ABIN658295) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the GFRA2 antibody detected the GFRA2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

GFRA2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen GFRA2 Interaktionspartner

Human GDNF Family Receptor alpha 2 (GFRA2) Interaktionspartner

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (zeige RET Antikörper) tyrosine kinase (zeige TXK Antikörper).

  2. High GFRalpha2 expression level leads to PTEN inactivation via Mir-17-5p up-regulation, promoting pancreatic tumor cell growth and chemoresistance.

  3. GFRA2 variants associated with diabetic neuropathic pain.

  4. The study shows co-localization of RET (zeige RET Antikörper) with GFRA1 (zeige GFRA1 Antikörper) and GFRA2 in myenteric ganglia of the adult human colon.

  5. Cyclic AMP (zeige APRT Antikörper) signalling through PKA but not Epac (zeige RAPGEF3 Antikörper) is essential for neurturin (zeige NRTN Antikörper)-induced biphasic ERK1/2 (zeige MAPK1/3 Antikörper) activation and neurite outgrowths through GFRalpha2 isoforms.

  6. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia.

  7. This study found nominally-significant evidence for interactions between GFRA1 (zeige GFRA1 Antikörper), 2 and 3 associated with schizophrenia and clozapine response, consistent with the locations of these three genes within linkage regions for schizophrenia.

  8. Both GFR (zeige RAPGEF5 Antikörper) alpha2a and GFR (zeige RAPGEF5 Antikörper) alpha2c, but not GFR (zeige RAPGEF5 Antikörper) alpha2b (zeige ADRA2B Antikörper), promote neurite outgrowth in transfected Neuro2A cells.

Mouse (Murine) GDNF Family Receptor alpha 2 (GFRA2) Interaktionspartner

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (zeige RET Antikörper) tyrosine kinase (zeige TYRO3 Antikörper).

  2. Ret (zeige RET Antikörper) and Gfra2 null mice display comparable early central projection deficits, but Gfra2 null rapidly adapting mechanoreceptors recover later.

  3. STAT3 (zeige STAT3 Antikörper) phosphorylation by neurturin (zeige NRTN Antikörper) was found to be mediated specifically by GFRalpha2c and RET9 (zeige RET Antikörper) isoforms.

  4. Cholinergic innervation of gastric mucosa depends on neurturin (zeige NRTN Antikörper)-GFRalpha2 signalling but is dispensable for gastrin (zeige GAST Antikörper) secretion and for basal and maximal acid output

  5. our data demonstrate that RET (zeige RET Antikörper)/GFRalpha signals are dispensable for thymic T cell development in vivo

  6. Transduction-function role for GFR (zeige RAPGEF5 Antikörper) alpha2/neurturin (zeige NRTN Antikörper) signalling in a specific class of sensory neurons.

  7. The cholinergic subpopulation of sympathetic neurons requires GFR alpha 2 signaling for soma size and for growth or maintenance of target innervation.

  8. Demonstrate a role for GFRalpha2-expressing enteric neurons in the downstream signaling of the glucagon (zeige GCG Antikörper)-like peptides to inhibit GI motility, but not in intestinal growth.

GFRA2 Antigen-Profil

Protein Überblick

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GFRA2

  • DKFZP459C0228 protein (DKFZP459C0228) Antikörper
  • GDNF family receptor alpha 2 (gfra2) Antikörper
  • GDNF family receptor alpha 2a (gfra2a) Antikörper
  • GDNF family receptor alpha 2 (GFRA2) Antikörper
  • GDNF family receptor alpha 2 (Gfra2) Antikörper
  • glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2) Antikörper
  • DKFZP459C0228 Antikörper
  • GDNFRB Antikörper
  • gfra2 Antikörper
  • NRTNR-ALPHA Antikörper
  • NTNRA Antikörper
  • NTNRALPHA Antikörper
  • Retl2 Antikörper
  • TRNR2 Antikörper

Bezeichner auf Proteinebene für GFRA2

DKFZP459C0228 protein , GFR-alpha-2 , GDNF family receptor alpha-2 , GDNF family receptor alpha 2 , glial cell line derived neurotrophic factor family receptor alpha 2 , GFR alpha 2 , GDNF family receptor alpha-2-like , GDNF receptor beta , GDNFR-alpha-2 , GDNFR-beta , GFR-alpha 2 , NTNR-alpha , PI-linked cell-surface accessory protein , RET ligand 2 , TGF-beta-related neurotrophic factor receptor 2 , TRN receptor, GPI-anchored , glial cell line derived neurotrophic factor receptor, beta , neurturin receptor alpha , GDNF receptor alpha-2 , tyrosine kinase receptor ligand 2 , NRTNR-alpha , GFR alpha-2

GENE ID SPEZIES
100189713 Pongo abelii
100127717 Xenopus (Silurana) tropicalis
405794 Danio rerio
100475044 Ailuropoda melanoleuca
2675 Homo sapiens
609172 Canis lupus familiaris
514036 Bos taurus
25136 Rattus norvegicus
395993 Gallus gallus
100171804 Pongo abelii
14586 Mus musculus
Ausgewählte Anbieter für anti-GFRA2 (GFRA2) Antikörper
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