anti-Formyl Peptide Receptor 1 (FPR1) Antikörper

FPR1 encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. Zusätzlich bieten wir Ihnen FPR1 Kits (9) und FPR1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FPR1 2357 P21462
FPR1 14293 P33766
FPR1 292409  
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Top anti-FPR1 Antikörper auf antikoerper-online.de

Showing 10 out of 108 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μL 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of FPR1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of FPR1 expression in U87MG (A) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of FPR1 expression in A549 (A), Raw264.7 (B), rat brain (C) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from K562 cells, using FPR1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using FPR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of A549 cells, using FPR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with FPR1 antibody ABIN297066 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-FPR1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-FPR1 antibody  ABIN1048603 IHC staining of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FPR1 antibody IHC of human spleen, red pulp. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-FPR1 antibody  ABIN1048604 IHC staining of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FPR1 antibody IHC of human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-FPR1 antibody  ABIN1048601 IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details

Am meisten referenzierte anti-FPR1 Antikörper

  1. Human Monoclonal FPR1 Primary Antibody für CyTOF, FACS - ABIN4899071 : Prevete, Liotti, Visciano, Marone, Melillo, de Paulis: The formyl peptide receptor 1 exerts a tumor suppressor function in human gastric cancer by inhibiting angiogenesis. in Oncogene 2015 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal FPR1 Primary Antibody für FACS - ABIN4895417 : Schneider, Weaver, Gaur, Tripathi, Jesaitis, Zelenka, Gao, Murphy: The leukocyte chemotactic receptor FPR1 is functionally expressed on human lens epithelial cells. in The Journal of biological chemistry 2012 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal FPR1 Primary Antibody für IHC, IHC (p) - ABIN4312515 : Gardner, Yazid, Ribeiro, Ali, Dick: Augmenting Endogenous Levels of Retinal Annexin A1 Suppresses Uveitis in Mice. in Translational vision science & technology 1970 (PubMed)

Weitere Antikörper gegen FPR1 Interaktionspartner

Human Formyl Peptide Receptor 1 (FPR1) Interaktionspartner

  1. The overexpression of formyl peptide receptor 1 may be related to drug-resistant bladder cancer and promotes the deterioration of drug-resistant bladder cancer.

  2. FPR1 may play an important role in tumor cell invasion in colorectal cancer patients.

  3. Results show high expression of FPR1 in triple-negative breast cancer (TNBC) and in lymph node metastasis. This expression level was positively correlated with that of AnxA1 in primary tumors. The autocrine activation of FPR1 by AnxA1 might be a pivotal target for TNBC.

  4. FPR1 mRNA levels in whole blood can predict the presence of lung cancer. Using this as a reflex test for positive lung cancer screening computed tomography scans has the potential to increase the positive predictive value.

  5. To develop enzyme-resistant analogues, we applied here the Retro-Inverso (RI) approach, whereby the topology of the side chains is maintained by inverting the sequence of the peptide and the chirality of all residues. Molecular dynamics suggests that peptide RI-3 adopts the turn structure typical of uPAR-FPR1 antagonists

  6. Authors found that the co-expression of uPAR and FPR1 confers to A375 and M14 melanoma cells a clear-cut capability to move towards chemotactic gradients, to cross extracellular matrix and endothelial monolayers. FPR1 activity is required, as cell migration and invasion were abrogated by receptor desensitization.

  7. Taken together, our results suggest that intracellular FPR in naive CD4 T cells and surface FPRs in activated CD4 T cells might regulate immune responses by regulating CD4 T cell activity.

  8. the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases

  9. The data demonstrate that FPR1 is involved in neuroblastoma development and could represent a therapy option for the treatment of neuroblastoma.

  10. FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2.

  11. Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.

  12. The inhibitory function of oxidant sensing by TRPM2 requires the oxidation of Cys549, which then induces TRMP2 binding to formyl peptide receptor 1 (FPR1) and subsequent FPR1 internalization and signaling inhibition

  13. FPR1 expression is significantly upregulated in human masticatory mucosa during wound healing

  14. FAM19A4 is a novel ligand of formyl peptide receptor 1.

  15. The authors describe here the activation of isolated human blood neutrophils by TcdB and, moreover, by toxin fragments generated by limited proteolytical digestion via the FPR1 receptor.

  16. these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.

  17. Data suggest that formyl peptide receptor 1 (FPR1) stimulation may represent a novel therapeutic approach to counteract tumor angiogenesis.

  18. a pepducin designed to target FPR1 was found to hijack FPR2 and potently inhibit neutrophil functions

  19. the co-upregulated expression of mast cell chymase and ANXA1-FPR1 system in ectopic endometrium suggests their involvement in the development of endometriotic lesions.

  20. FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative age-related macular degeneration and polypoidal choroidal vasculopathy .

Mouse (Murine) Formyl Peptide Receptor 1 (FPR1) Interaktionspartner

  1. Fpr1 activation induces actin polymerization in wild type vascular smooth muscle cells. Absence of Fpr1 in the vasculature significantly decreased vascular contraction and induced loss of myogenic tone to elevated intraluminal pressures via disruption of actin polymerization.

  2. Mouse neutrophils lacking formyl peptide receptors (Fpr1/2(-/-)) are defective in the phagocytosis of Escherichia coli and the chemoattractant N-formyl-Met-Leu-Phe (fMLP)-coated beads.

  3. Study showed significantly increased expression of FPR1 and FPR2, during differentiation of neural stem cells (NSCs). The activation of FPRs promotes NSCs to differentiate into neurons with more primary neurites and branch points and longer neurites per cell. Meanwhile, this activation also inhibits the differentiation of NSCs into astrocytes.

  4. FPR1-deficient mice showed a slight but significant decrease of demyelination in the corpus callosum and reduced glial cell activation.

  5. the FPR1 downstream signaling pathways were competitively inhibited by HCH6-1. Furthermore, HCH6-1 prevented pulmonary neutrophil infiltration and edema along with alveolar damage in LPS-induced ALI in mice. Our findings suggest that HCH6-1, a FPR1 antagonist, may have potential as a new therapeutic agent for treating FPR1-involved inflammatory lung diseases

  6. Intravital TPLSM revealed that formyl-peptide-FPR1 signaling is responsible for regulating neutrophil chemotaxis to allow migration into the necrotic area in hepatic ischemia-reperfusion injury

  7. FAM3D plays a role in gastrointestinal homeostasis and inflammation through its receptors FPR1 and FPR2.

  8. Formylated MHC class Ib binding peptides activate both human and mouse neutrophils primarily through FPR1.

  9. Blocking of FPR1 completely abrogated the fMet-Leu-Phe-, gliadin- and synthetic peptide-induced migration.

  10. these results highlight the importance of FPR1 in chemotherapy-induced anticancer immune responses.

  11. Ovalbumininduced airway inflammation is mediated by upregulation of the TLR2/MyD88/NFkappaB signaling pathway and inhibition of LXA4R.

  12. Deficiency of formyl peptide receptor 1 is associated with increased inflammation and enhanced liver injury after LPS-stimulation

  13. Fpr1/2 are critical for normal healing of the sterile skin wound by mediating the first wave of neutrophil infiltration.

  14. these findings identify a novel role of FPR1 as pattern recognition receptors for perceiving the enteric microbiota that promotes repair of mucosal wounds via generation of reactive oxygen species from the enterocyte NOX1.

  15. FPR1 and FPR2 play an important role in the innate immune responses against Streptococcus pneumoniae within the central nervous system and the lack of the receptors leads to a dysregulation of the inflammatory response compared with wild-type mice.

  16. mediates neutrophil recruitment in acute lung injury

  17. Further, these results reveal Fpr1 as a major mediator of host commensal interaction during dysbiosis.

  18. The mechanism involved impaired early neutrophil recruitment to the liver with Fpr1 being sole receptor for neutrophils to sense Listeria chemoattractant signals and for production of bactericidal superoxide.

  19. findings may have clinical significance because current smokers and subjects with emphysema showed increased FPR expression in bronchoalveolar fluids and on peripheral neutrophils

  20. Neutrophil migration into the inflamed mouse colon does not depend on FPR1, but FPR1 contributes in other pathological mechanisms that are harmful during acute inflammation but are protective during chronic inflammation.

FPR1 Antigen-Profil

Protein Überblick

This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.

Genbezeichner und Symbole assoziert mit FPR1

  • formyl peptide receptor 1 (FPR1) Antikörper
  • formyl peptide receptor 1 (Fpr1) Antikörper
  • fMLF-R Antikörper
  • FMLP Antikörper
  • FPR Antikörper
  • FPR1 Antikörper
  • LXA4R Antikörper

Bezeichner auf Proteinebene für FPR1

N-formylpeptide chemoattractant receptor , fMLP receptor , fMet-Leu-Phe receptor , N-formyl peptide receptor , lipoxin A4 receptor

GENE ID SPEZIES
2357 Homo sapiens
14293 Mus musculus
292409 Rattus norvegicus
456254 Pan troglodytes
100443662 Pongo abelii
100009153 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-FPR1 (FPR1) Antikörper
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