FPR1 Antikörper
Kurzübersicht für FPR1 Antikörper (ABIN615853)
Target
Alle FPR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- FPR1 Antibody detects endogenous levels of total FPR1 protein.
-
Aufreinigung
- Immunoaffinity Chromatography
-
Immunogen
- Synthetic peptide - KLH conjugated, Synthetic peptide Genename: FPR1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1,0 mg/mL
-
Buffer
- PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- -20 °C
-
-
- FPR1 (Formyl Peptide Receptor 1 (FPR1))
-
Andere Bezeichnung
- fMLP Receptor
-
Hintergrund
- Formyl peptide receptor 1, a Chemoattractant Receptor, mediates chemotaxis, degranulation, and superoxide production, as part of the inflammatory response. Bacterial N-formylmethionyl peptides and Annexin A1, specific ligands for FPR1, attract polymorphonuclear neutrophils to sites of infection. FPR receptors promote the phosphorylation and downregulation of CCR5, which has been shown to inhibit HIV infection. Therefore, ligands for an FPR receptor may be able to inhibit HIV infection.Synonyms: FPR1, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor, fMet-Leu-Phe receptor
-
Gen-ID
- 2357
-
NCBI Accession
- NP_001180235
-
UniProt
- P21462
Target
-