anti-Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) Antikörper

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009].. Zusätzlich bieten wir Ihnen EZH1 Kits (10) und EZH1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EZH1 2145 Q92800
EZH1 14055 P70351
EZH1 303547  
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Top anti-EZH1 Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-EZH1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  COLO205 cell lysate There is BioGPS gene expression data showing that EZH1 is expressed in COLO205 Immunohistochemistry with Spleen tissue at an antibody concentration of 5µg/ml using anti-EZH1 antibody (ARP38092_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert ChIP, WB Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. WB Suggested Anti-EZH1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184879 staining (2µg/ml) of MOLT-4 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Rind (Kuh) Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of EZH1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of EZH1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western Blot: EZH1 Antibody [ABIN43098228] - Detection of EZH1 in mouse (lane 1) and human (lane 2) spleen lysate using this antibody at 2 ug/ml. Western Blot: EZH1 Antibody [ABIN43098228] - WB detection of EZH1 protein in (A ) Ramos cells lysate, (B) Daudi cells lysate and (C) Peptide blocked - Daudi cells lysate by using EZH1 antibody at a concentration of 2 ug/ml. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from HT-29/LOVO/A549/NIH-3T3/RAW264.7/COS7 cells, using EZH1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using EZH1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-EZH1 Antibody (Center) (ABIN389082) in 293 cell line lysates (35 µg/lane). EZH1(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Ziege Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$610.50
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB Anti-EZH1 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958979 concentration 5 ug/ml. Anti-EZH1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other form ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details

EZH1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-EZH1 Antikörper

  1. Human Polyclonal EZH1 Primary Antibody für ELISA, WB - ABIN249717 : Abel, Brody, Valdes, Erdos, McKinley, Castilla, Merajver, Couch, Friedman, Ostermeyer, Lynch, King, Welcsh, Osborne-Lawrence, Spillman, Bowcock, Collins, Weber: Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1. in Genomics 1997 (PubMed)

  2. Human Polyclonal EZH1 Primary Antibody für WB - ABIN4309822 : Grimaldi, Christian, Steel, Henriet, Poutanen, Brosens: Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal cells. in Molecular endocrinology (Baltimore, Md.) 2011 (PubMed)

Weitere Antikörper gegen EZH1 Interaktionspartner

Human Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) Interaktionspartner

  1. identification of EZH1 as a repressor of haematopoietic multipotency in the early mammalian embryo

  2. pVHL (zeige VHL Antikörper) loss causes the transcriptional activation of hypoxia-inducible factor (HIF) target genes, including many genes that encode histone lysine demethylases.

  3. Data show that embryonic stem cells with deletion of EZH1 or EZH2 (zeige EZH2 Antikörper) fail to differentiate into ectoderm lineages.

  4. Expression of the EZH2 (zeige EZH2 Antikörper) homolog EZH1 is reduced in EZH2 (zeige EZH2 Antikörper)-deficient CML (zeige BCR Antikörper) LICs, creating a scenario resembling complete loss of PRC2. EZH2 (zeige EZH2 Antikörper) dependence of CML (zeige BCR Antikörper) LICs raises prospects for improved therapy of TKI-resistant CML (zeige BCR Antikörper) and/or eradication of disease by addition of EZH2 (zeige EZH2 Antikörper) inhibitors

  5. a hot-spot mutation in EZH1 is the second most frequent genetic alteration in autonomous thyroid adenomas; the association between EZH1 and TSHR (zeige TSHR Antikörper) mutations suggests a 2-hit model for the pathogenesis of these tumors, whereby constitutive activation of the cAMP pathway and EZH1 mutations cooperate to induce the hyperproliferation of thyroid cells

  6. EZH1, SUZ12 and UXT (zeige UXT Antikörper) work synergistically to regulate pathway activation in the nucleus.

  7. The authors report a novel PRC2-Ezh1 function that utilizes Ezh1beta as an adaptive stress sensor in the cytoplasm, thus allowing postmitotic cells to maintain tissue integrity in response to environmental changes.

  8. These evidences suggest that EZH2 (zeige EZH2 Antikörper) and EZH1 are important in the counter-balancing mechanisms controlling proliferation/resting of lymphoid cells. The disruption of the balanced EZH2/EZH1 (zeige EZH2 Antikörper) ratio may play important roles in the pathogenesis of lymphomas

  9. The related enzymatic subunits EZH1 and EZH2 (zeige EZH2 Antikörper) undergo an expression switch during blood cell development.

  10. EZH1 maintains repressive chromatin through different mechanisms.

Mouse (Murine) Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) Interaktionspartner

  1. The combined loss of Ezh1 and Ezh2 (zeige EZH2 Antikörper) in chondrocytes severely impairs skeletal growth in mice.

  2. identification of EZH1 as a repressor of haematopoietic multipotency in the early mammalian embryo

  3. Suggest that EZH1 and -2 are novel targets of miR (zeige MLXIP Antikörper)-214-3p, and miR (zeige MLXIP Antikörper)-214-3p might be one potential miRNA for the prevention of cardiac fibrosis.

  4. Ezh1 is required for neonatal heart regeneration and development.

  5. in the skin epithelium, EED (zeige EED Antikörper), Suz12, and Ezh1/2 function largely as subunits of the PRC2 complex and have roles in skin development

  6. the expression level of Ezh1 determines the restoration of H3K27 methylation in the absence of the canonical EZH2 (zeige EZH2 Antikörper)-PRC2.

  7. These results clearly demonstrated an essential role of Ezh1 in the pathogenesis of hematopoietic malignancies induced by Ezh2 (zeige EZH2 Antikörper) insufficiency, and highlighted the differential functions of Ezh1 and Ezh2 (zeige EZH2 Antikörper) in hematopoiesis.

  8. Loss of EZH1 is associated with increased liver injury and a blunted regenerative response.

  9. Data show that histone lysine methyltransferase Ezh1 promotes toll (zeige TLR4 Antikörper)-like receptor (TLR)-triggered inflammatory cytokine production by suppressing the Toll-interacting protein (Tollip (zeige TOLLIP Antikörper)), contributing to full activation of the innate immunity.

  10. presence of Ezh1 helps to maintain PRC2 occupancy on its target genes in myoblasts where Jarid2 (zeige JARID2 Antikörper) is not expressed.

Xenopus laevis Enhancer of Zeste Homolog 1 (Drosophila) (EZH1) Interaktionspartner

  1. Study shows that the PRC2 core components are enriched in retinal progenitors and downregulated in differentiated cells. Knockdown of the PRC2 core component Ezh2 (zeige EZH2 Antikörper) leads to reduced retinal progenitor proliferation.

EZH1 Antigen-Profil

Protein Überblick

EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008

Genbezeichner und Symbole assoziert mit EZH1

  • enhancer of zeste 1 polycomb repressive complex 2 subunit (EZH1) Antikörper
  • histone-lysine N-methyltransferase EZH1-like (LOC100221384) Antikörper
  • enhancer of zeste 1 polycomb repressive complex 2 subunit (ezh1) Antikörper
  • enhancer of zeste 1 polycomb repressive complex 2 subunit (Ezh1) Antikörper
  • enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog (ezh2.L) Antikörper
  • AW557915 Antikörper
  • enx-1 Antikörper
  • enx1 Antikörper
  • ezh1 Antikörper
  • ezh2 Antikörper
  • kmt6 Antikörper
  • KMT6B Antikörper
  • mKIAA0388 Antikörper
  • si:ch211-250i3.1 Antikörper
  • xez Antikörper
  • zgc:136829 Antikörper

Bezeichner auf Proteinebene für EZH1

enhancer of zeste homolog 1 (Drosophila) , enhancer of zeste homolog 1-like , histone-lysine N-methyltransferase EZH1-like , ENX-2 , histone-lysine N-methyltransferase EZH1 , enhancer of zeste 1 , enhancer of zeste homolog 1 , Enhancer of zeste homolog 2-A , Polycomb protein EZH2-A , histone-lysine N-methyltransferase EZH2

GENE ID SPEZIES
454697 Pan troglodytes
100052411 Equus caballus
100221384 Taeniopygia guttata
100351852 Oryctolagus cuniculus
100411881 Callithrix jacchus
100547448 Meleagris gallopavo
100559669 Anolis carolinensis
100604860 Nomascus leucogenys
2145 Homo sapiens
14055 Mus musculus
533087 Bos taurus
303547 Rattus norvegicus
664754 Danio rerio
420023 Gallus gallus
480516 Canis lupus familiaris
100518394 Sus scrofa
100720693 Cavia porcellus
399174 Xenopus laevis
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