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E2F6 encodes a member of the E2F transcription factor protein family. Zusätzlich bieten wir Ihnen E2F6 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Cow (Bovine) Polyclonal E2F6 Primary Antibody für IHC, WB - ABIN2779510
Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006
Show all 2 Pubmed References
Human Polyclonal E2F6 Primary Antibody für ELISA, WB - ABIN4306784
McLaughlin-Drubin, Huh, Münger: Human papillomavirus type 16 E7 oncoprotein associates with E2F6. in Journal of virology 2008
This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms.
E2F transcription factor 6
, transcription factor E2F6
, E2F-binding site-modulating activity protein
, transcriptional repressor E2F6