Creatine Kinase, Brain Proteine (CKB)

The protein encoded by CKB is a cytoplasmic enzyme involved in energy homeostasis. Zusätzlich bieten wir Ihnen Creatine Kinase, Brain Antikörper (232) und Creatine Kinase, Brain Kits (69) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CKB 1152 P12277
CKB 12709 Q04447
CKB 24264 P07335
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Showing 10 out of 36 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Baculovirus infected Insect Cells Human His tag 50 μg Anmelden zum Anzeigen 14 bis 16 Tage
$311.24
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$666.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$340.00
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Escherichia coli (E. coli) Human Unkonjugiert 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Escherichia coli (E. coli) Hund Unkonjugiert SDS-PAGE analysis of Dog Creatine Kinase, Brain Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$668.03
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Escherichia coli (E. coli) Ratte His tag   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$560.00
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Hefe REACT_Dogfish His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,025.83
Details

CKB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , , ,
, ,
Mouse (Murine) , ,

Rat (Rattus) ,

Am meisten referenzierte Creatine Kinase, Brain Proteine

  1. Human CKB Protein expressed in Escherichia coli (E. coli) - ABIN624668 : Mitsakakis, Gizeli: Detection of multiple cardiac markers with an integrated acoustic platform for cardiovascular risk assessment. in Analytica chimica acta 2011 (PubMed)

Weitere Proteine zu Creatine Kinase, Brain (CKB) Interaktionspartnern

Human Creatine Kinase, Brain (CKB) Interaktionspartner

  1. The data revealed a varying but significant increase of CK activity in CKBE individuals as compared to controls, reaching an almost 800-fold increase in two CKBE individuals which also had increased erythrocyte creatine.

  2. Association and oligomerization of Prx II could take part in recovery and protection of the CK BB enzyme activity from inactivation during heat-induced stress.

  3. membrane localization of BCK seems to be an important and regulated feature for the fueling of membrane-located, ATP-dependent processes, stressing again the importance of local rather than global ATP concentrations.

  4. These findings support increased CK activity as protection against ischaemia-reperfusion injury, in particular, protection via CKMT2 in a cardiac-relevant cell line, which merits further investigation in vivo.

  5. SRC, LYN and CKB expression or DNA methylation could be useful markers for predicting tumor progression.

  6. CK-MB levels were higher after ERCP in non-ischemic patients compared with a myocardial ischemia group. Creatine phosphokinase levels did not differ significantly between groups.

  7. CK-B catalytic activity also helps in the formation of protrusive ruffle structures which are actin-dependent and abundant on the surface of both unstimulated and LPS-activated macrophages.

  8. increased serum Ckbb reflects failure of osteoclasts or suppression of osteoclasts in children with osteogenesis imperfecta during neridronate treatment

  9. Estimation of CK and its CK isoenzyme fractions can aid in quick and accurate diagnosis of tubal ectopic pregnancy.

  10. effects of osmolytes on human brain-type creatine kinase folding

  11. We found that most patients with macular telangiectasia-2 possess retinal autoantibodies, the most prevalent of which were directed against AGL, RBP3, and CK-B.

  12. analysis of SNPs and their effect on creatine kinase structure and function

  13. study found promoter SNPs of CKB and TPI1 were weakly associated with schizophrenia;in addition, IFNG polymorphisms were associated with schizophrenia; results suggest that IFNG and proteins affected by IFNG may play a role in the pathogenesis of schizophrenia

  14. de-methylated CKB gene is inherited that leads to high CKB expression levels in myeloic precursor cells in the bone marrow

  15. His103 and Phe107 in hASB9-2 are essential for binding to CKB.

  16. Cigarette smoke induced carbonylation and subsequent degradation of creatine kinase B are involved in the regulation of senescence in bronchial epithelial cells.

  17. The results suggested that the intra- and inter-subunit domain interactions modified the behavior of kinetic refolding.

  18. Data demonstrate that the downregulation of CKB may play an important role in colon cancer progression by promoting EMT.

  19. CKB was up-regulated in women older than 38 years, and its expression in cumulus cells was associated with embryo quality

  20. These observations suggested that the ability to generate the oxidized form could protect BBCK against the intracellular oxidative stress.

Rabbit Creatine Kinase, Brain (CKB) Interaktionspartner

  1. The effect of Zn(2+) on the folding and aggregation of brain creatine kinase (CK-BB), was studied.

  2. report the identity of a 45 kDa imidazoline binding protein to be brain creatine kinase and this enzyme possesses an I2 binding site; findings will undoubtedly contribute to greater understanding of and development of imidazoline therapeutic drugs.

Mouse (Murine) Creatine Kinase, Brain (CKB) Interaktionspartner

  1. Loss of normal CKB structure and function contributes to the mechanisms by which isoaspartate accumulation leads to central nervous system dysfunction in the PIMT-Knockout mouse.

  2. CKB plays a key role in myotube formation by limiting myoblast fusion during myogenesis.

  3. BCK phosphorylation at Ser6 did not affect its enzymatic activity, but led to the appearance of the phosphorylated enzyme at the endoplasmic reticulum (ER)

  4. Hypothalamic plasticity of neuropeptide Y is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation

  5. negative regulation of CKB by mHTT is a key event in the pathogenesis of HD and contributes to the neuronal dysfunction associated with HD.

  6. reduced expression of brain creatine kinase in the cochlea of Huntington disease mice is associated with hearing impairment

  7. The comparison of protein patterns obtained with neural and non-neural derivatives of EC cell lines indicates changes are specific for the neural pathway, including the accumulation of the brain isozyme of creatine phosphokinase.

  8. In rat cerebrum and cerebellum, as in rat heart, at all ages the several cCK isoenzymes do participate in a gender-specific manner, in favor of females, in diverse functions of the different cell compartments of glial and neuronal cells.

  9. CK-B was expressed selective to astrocytes among glial populations, and was exclusive to inhibitory neurons among neuronal populations.

  10. Brain type and mitochondrial ubiquitous CK double knockout mice have a reduced body weight, and demonstrate a severely impaired spatial learning in both a dry and a wet maze, lower nestbuilding activity and diminished acoustic startle reflex responses.

  11. Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption.

  12. cytoskeletal dynamics during cell motility is coupled to on-site availability of ATP generated by CKB

  13. Here, we report on the coupling of CK activity to body temperature rhythm and adaptive thermoregulation

Creatine Kinase, Brain (CKB) Protein Überblick

Protein Überblick

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.

Genbezeichner und Symbole assoziert mit Creatine Kinase, Brain Proteine (CKB)

  • creatine kinase B (CKB)
  • creatine kinase, brain L homeolog (ckb.L)
  • creatine kinase B-type (CKB)
  • creatine kinase, brain (Ckb)
  • creatine kinase, brain (ckb)
  • creatine kinase, brain b (ckbb)
  • creatine kinase, brain (CKB)
  • creatine kinase B (Ckb)
  • b-ck Protein
  • bck Protein
  • cb594 Protein
  • Ck-3 Protein
  • Ck3 Protein
  • ckb Protein
  • Ckbb Protein
  • Ckbr Protein
  • wu:fj36f10 Protein
  • wu:fj37d11 Protein

Bezeichner auf Proteinebene für Creatine Kinase, Brain Proteine (CKB)

creatine kinase B chain , creatine kinase B-type , creatine kinase-B , B-CK , brain creatine kinase , creatine kinase, brain , creatine kinase B , B-creatine kinase , alternate protein , brain creatine kinase b , Creatine kinase B chain , Creatine kinase B-type

GENE ID SPEZIES
1152 Homo sapiens
100009085 Oryctolagus cuniculus
380055 Xenopus laevis
100190977 Ovis aries
453185 Pan troglodytes
516210 Bos taurus
12709 Mus musculus
733543 Xenopus (Silurana) tropicalis
396248 Gallus gallus
140744 Danio rerio
711167 Macaca mulatta
24264 Rattus norvegicus
100627332 Sus scrofa
100735800 Cavia porcellus
100855552 Canis lupus familiaris
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