anti-Collagen, Type III (COL3) Antikörper

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. Zusätzlich bieten wir Ihnen Collagen, Type III Kits (69) und Collagen, Type III Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COL3 2147 P00734
COL3 14061 P19221
COL3 29251  
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Top anti-Collagen, Type III Antikörper auf antikoerper-online.de

Showing 10 out of 169 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded dog bladder tissue labeled with Anti-Collagen III Polyclonal Antibody (ABIN669981), Unconjugated at 1:800, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human myocardium tissue labeled with Anti-Collagen III Polyclonal Antibody (ABIN669981), Unconjugated at 1:400, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$329.45
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Collagen III Polyclonal Antibody, Unconjugated (ABIN730168) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Collagen III Polyclonal Antibody, Unconjugated  at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$329.45
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human pancreas tissue, using Collagen III Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using Collagen III Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB ABIN6266516 staining BJ cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibody. Western blot analysis of extracts from Hela, using Collagen III Antibody.,The lane on the left is treated with the antigen-specific peptide. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Ziege Unkonjugiert ELISA Paraffin embedded human gastric cancer tissue was stained with Goat IgG-UNLB isotype control, DAB, and hematoxylin. 0.2 mg Anmelden zum Anzeigen 3 bis 4 Tage
$408.00
Details
Rind (Kuh) Kaninchen FITC ELISA, IHC, IP, WB anti collagen III antibody (600-401-105 Lot 26016, 1:400, 45 min RT) showed strong staining in FFPE sections of human skin(left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue between seminiferous tubules. The antibody showed strong extracellular staining within connective tissues across many organs with minimal background staining. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA 50 μg Anmelden zum Anzeigen 5 bis 7 Tage
$598.50
Details
Rind (Kuh) Kaninchen HRP ELISA, IHC, IP, WB anti collagen III antibody (600-401-105 Lot 26016, 1:400, 45 min RT) showed strong staining in FFPE sections of human skin(left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue between seminiferous tubules. The antibody showed strong extracellular staining within connective tissues across many organs with minimal background staining. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA 50 μg Anmelden zum Anzeigen 5 bis 7 Tage
$598.50
Details
Rind (Kuh) Kaninchen Biotin ELISA, IHC, IP, WB anti collagen III antibody (600-401-105 Lot 26016, 1:400, 45 min RT) showed strong staining in FFPE sections of human skin(left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue between seminiferous tubules. The antibody showed strong extracellular staining within connective tissues across many organs with minimal background staining. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA 100 μg Anmelden zum Anzeigen 5 bis 7 Tage
$598.50
Details
Rind (Kuh) Kaninchen Unkonjugiert ELISA, IHC, IP, WB anti collagen III antibody (600-401-105 Lot 26016, 1:400, 45 min RT) showed strong staining in FFPE sections of human skin(left, dermis) with moderate to strong red staining and testis (right) where strong staining was observed within connective tissue between seminiferous tubules. The antibody showed strong extracellular staining within connective tissues across many organs with minimal background staining. Slides were steamed in 0.01 M sodium citrate buffer, pH 6.0 at 99-100°C - 20 minutes for antigen retrieval. Images provided courtesy of LifeSpan Biosciences, Seattle, WA Western Blot of Rabbit Anti-COLLAGEN III Antibody Lane 1: Human Collagen III Load: 100 ng per lane Primary antibody: Collagen III Antibody at 1:1000 o/n at 4°C Secondary antibody: 649 Goat anti-rabbit at 1:20,000 for 30 min at RT Block: ABIN925618 for 30 min at RT Predicted/Observed size: 138 kDa, 138 kDa 100 μg Anmelden zum Anzeigen 5 bis 7 Tage
$598.50
Details
Human Maus Unkonjugiert WB 100 μL Anmelden zum Anzeigen Verfügbar
$181.73
Details

Am meisten referenzierte anti-Collagen, Type III Antikörper

  1. Human Polyclonal COL3 Primary Antibody für IF (p), IHC (p) - ABIN669981 : Zhu, Hu, Yu, Ren, Hu: High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium. in Medical science monitor : international medical journal of experimental and clinical research 2016 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal COL3 Primary Antibody für ELISA - ABIN135050 : Karamichos, Hutcheon, Zieske: Transforming growth factor-β3 regulates assembly of a non-fibrotic matrix in a 3D corneal model. in Journal of tissue engineering and regenerative medicine 2011 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal COL3 Primary Antibody für IHC (fro), IHC (p) - ABIN2473051 : Tauler, Lange, el-Maghrabi, Pilkis: Expression of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and its kinase domain in Escherichia coli. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)
    Show all 4 Pubmed References

  4. Human Polyclonal COL3 Primary Antibody für ELISA, ICC - ABIN6260941 : Yang, Zhou, Zhu, Fan, Liu, Duan, Tang, Shou, Zuo: miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition. in Journal of gastroenterology and hepatology 2018 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal COL3 Primary Antibody für IF (p), IHC (p) - ABIN730168 : Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious. in International journal of clinical and experimental pathology 2015 (PubMed)

  6. Human Polyclonal COL3 Primary Antibody für ICC, IHC (fro) - ABIN1172519 : Li, Kong, Ma, Gao, Ma: Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-β1 with concomitant induce Smad7 in human hypertrophic scar fibroblasts. in International journal of clinical and experimental medicine 2015 (PubMed)

  7. Rat (Rattus) Polyclonal COL3 Primary Antibody für IHC (fro), IF - ABIN2473053 : Jones, Bigley, Pemberton, Randall et al.: Quantitative histopathological assessment of retardation of islets of langerhans degeneration in rosiglitazone-dosed obese ZDF rats using combined insulin and collagens (I and III) ... in Toxicologic pathology 2013 (PubMed)

  8. Cow (Bovine) Polyclonal COL3 Primary Antibody für ELISA, IHC - ABIN214580 : Jeong, Luo, Li, Strokes, Piao: Characterization of G protein-coupled receptor 56 protein expression in the mouse developing neocortex. in The Journal of comparative neurology 2012 (PubMed)

Weitere Antikörper gegen Collagen, Type III Interaktionspartner

Human Collagen, Type III (COL3) Interaktionspartner

  1. Occlusion of anion-binding exosite 2 in meizothrombin explains its impaired ability to activate factor V.

  2. Prothrombin conversion is accelerated in the antiphospholipid syndrome and insensitive to thrombomodulin.

  3. Mutation p.Tyr434His in F2 segregated with thrombosis within the family. Tyr434His in F2 is at the target site of arthropod bleeding toxin.

  4. Thrombin generation increases between the up- and downregulation phases of In Vitro Fertilization (IVF). No correlation between thrombin generation and TFPI was shown during IVF.

  5. Elevated plasma levels of procoagulant factors, such as FVIII or prothrombin, enhanced thrombin generation and reduced the amount of TF required for the initiation of thrombin formation.

  6. When endothelial cells are incubated with antiphospholipid antibodies thrombin generation is increased.

  7. No significant difference in FVL genotype between patients and controls was observed, whereas high frequencies of PRT G20210A, MTHFR C677T and MTHFR A1298C mutations in the Hb S patients

  8. This study proved that Berberine (BBR) is a direct thrombin inhibitor that has activity in inhibiting thrombin-induced platelet aggregation. BBR may be a potential candidate for the development of safe and effective thrombin-inhibiting drugs

  9. Thrombin generation had a limited impact as biomarker of venous thromboembolism.

  10. results explain the reduced pro-coagulant activity of the W215A mutant and demonstrate the allosteric connection between Trp215, the sodium-binding loop, and the active site

  11. Polymorphisms of F2, PROC, PROZ, and F13A1 Genes are Associated With Recurrent Spontaneous Abortion in Chinese Han Women.

  12. the prothrombotic activity of FII is the result of a polymorphism and of a missense mutation, whereas that of FV derives only from a polymorphism. The observation that a clotting factor defect may be associated with both bleeding or venous thrombosis depending on the site of the mutation has caused an extensive reevaluation of the blood clotting mechanism.

  13. Findings provide evidence for a relationship between two genes-three mutations-of the cardiovascular disease (CVD genes panel and recurrent pregnancy loss (RPL). These genotypes include the heterozygous state of the factor II G20210A mutation.

  14. digestion of thrombin by P. aeruginosa elastase leads to the release of the C-terminal thrombin-derived peptide FYT21, which inhibits pro-inflammatory responses to several pathogen-associated molecular patterns.

  15. Prothrombin gene mutation is rare in Budd-Chiari syndrome patients in India.

  16. In HBV-related cirrhosis, the combination of miR-122, AFP and PIVKA-II enables the identification of patients at higher risk of hepatocellular carcinoma development.

  17. Data, including data using network analysis, suggest that angiotensinogen (AGT), mitogen-activated protein kinase-14 (MAPK14), and prothrombin (F2) in placental villous tissues are core factors in early embryonic development; these studies involved proteomics and bioinformatics analysis of altered protein expression in placental villous tissue from early recurrent miscarriage patients in comparison to control tissues.

  18. Arg596Gln mutation is a risk factor for Chinese patients with venous thromboembolism due to its moderately decreased clotting activity but strong resistance to antithrombin inhibition.

  19. The induction of TG by BXPC3 cells was mainly driven by the TF pathway while TG generation triggered by MCF7 cells was also driven by FXII activation.

  20. we were not able to confirm the association between the polymorphisms of f5, f2, and mthfr and pregnancy loss in Bosnian women

Mouse (Murine) Collagen, Type III (COL3) Interaktionspartner

  1. These results suggested that the thrombinstimulated synthesis of IL6 was limited by HSP90 in osteoblasts, and that the effects of HSP90 were exerted at the point between Rhokinase and p38 MAPK.

  2. Platelet derived microparticles formed in sepsis are a potent inducer of thrombin generation via phosphatidylserine exposure, and activation of both the intrinsic and extrinsic pathway of coagulation.

  3. These findings imply that a thrombin-pericyte interaction in the brain could be a significant mechanism responsible for blood-brain barrier dysfunction under obesity-associated diabetic conditions and thus could represent a therapeutic target for central nervous system complications of diabetes.

  4. mutations were introduced into the endogenous fII gene, resulting in expression of prothrombin carrying 3 amino acid substitutions (R157A, R268A, and K281A) to limit activation events to yield only fIIa(Meizothrombin) Homozygous fII(MZ) mice are viable, express fII levels comparable with fII(Wild type) mice, and have reproductive success.

  5. Biglycan plays a protective role during the progression of atherosclerosis in ApoE-deficient mice by inhibiting thrombin generation.

  6. allosteric inhibitor SbO4L targets the glycoprotein Ibalpha-binding and heparin-binding site of thrombin

  7. thrombin/PAR-1 interaction regulated MCP-1, TF, MCSF and IL-6 production.

  8. Observations illustrate the role of thrombin as a pleiotropic atherogenic molecule under conditions of hypercholesterolemia and suggest the utility of its inhibition with locally acting antithrombin nanoparticle therapeutics.

  9. Thrombin-PAR1 signaling, via nitric oxide and EPCR, promotes hematopoietic stem cell (HSC) mobilization.

  10. Primary tumor growth by colon cancer cells was reduced by reduction of circulating prothrombin. There were lower mitotic indices and invasiveness. This growth relied upon 2 targets of thrombin-mediated proteolysis, protease: PAR-1 and fibrinogen.

  11. Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase C epsilon.

  12. thrombin/PAR1 pathway as a novel target for developing therapeutic strategies to restore synaptic function in the acute phase of ischemic stroke.

  13. High Factor IIa expression is associated with multiorgan pathologies in sickle cell disease.

  14. Blockage of thrombin exosites with compounds specific for exosite I (hirudin and HD1 aptamer) or exosite II (heparin and HD22 aptamer) impaired the COMP-thrombin interaction, indicating a 2-site binding mechanism.

  15. Whole blood thrombin generation assay is capable of detecting a prothrombotic phenotype in Bmal1-KO mice.

  16. Fyn, but not Lyn, was required for complete Pyk2 phosphorylation by thrombin.

  17. Thrombin cleavage of osteopontin disrupts a pro-chemotactic sequence for dendritic cells, which is compensated by the release of its pro-chemotactic C-terminal fragment.

  18. The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth.

  19. Influenza virus H1N1 activates platelets through FcgammaRIIA signaling and thrombin generation.

  20. These results indicate that thrombin acts through multiple mechanisms to activate MMPs and PGE2 synthesis in amnion.

Collagen, Type III (COL3) Antigen-Profil

Protein Überblick

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

Genbezeichner und Symbole assoziert mit COL3

  • coagulation factor II, thrombin (F2) Antikörper
  • coagulation factor II (F2) Antikörper
  • Cf-2 Antikörper
  • Cf2 Antikörper
  • FII Antikörper
  • prothrombin Antikörper
  • PT Antikörper
  • RPRGL2 Antikörper
  • THPH1 Antikörper
  • thrombin Antikörper

Bezeichner auf Proteinebene für COL3

prepro-coagulation factor II , prothrombin , prothrombin B-chain , serine protease , coagulation factor 2 , thrombin

GENE ID SPEZIES
2147 Homo sapiens
14061 Mus musculus
29251 Rattus norvegicus
395306 Gallus gallus
Ausgewählte Anbieter für anti-Collagen, Type III (COL3) Antikörper
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