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May be a regulator of keratinocyte proliferation or differentiation (By similarity). Zusätzlich bieten wir Ihnen Coiled-Coil alpha-Helical Rod Protein 1 Kits (12) und Coiled-Coil alpha-Helical Rod Protein 1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes
CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding
Confocal imaging confirmed the localization of CCHCR1 in P-bodies.
The centrosomal localization of CCHCR1 provides a connection to the abnormal cell proliferation and offers a link to possible cellular pathways altered in psoriasis.
Psoriasis is associated with genetic polymorphism in the CCHCR1 gene and in a genomic segment flanking the HLA-C region in the North Indian population.
Isolated by a two hybrid assay, StAR binding protein binds StAR protein in cells and enhances the ability of StAR protein to promote syntheses of steroid hormones.(sTAR binding protein)
These studies show that miR-122, a 22-nucleotide microRNA, is derived from a liver-specific noncoding polyadenylated RNA transcribed from the gene hcr.
These results suggest a role for CCHCR1 in the pathogenesis of psoriasis via the regulation of skin steroid metabolism.
Results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of psoriasis are predictably highly similar in a Finnish nationwide cohort of 379 psoriasis patients.
the aberrant function of CCHCR1 may lead to abnormal keratinocyte proliferation which is a key feature of psoriatic epidermis.
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression
May be a regulator of keratinocyte proliferation or differentiation (By similarity).
HCR (a-helix coiled-coil rod homologue)
, StAR-binding protein
, alpha-helical coiled-coil rod protein
, putative gene 8 protein
, HCR (a-helix coiled-coil rod homolog)
, a-helix coiled-coil rod homolog
, alpha helical coiled-coil rod protein
, tricohyalin homologue
, coiled-coil alpha-helical rod protein 1