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The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Zusätzlich bieten wir Ihnen CHRNB3 Proteine (13) und CHRNB3 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 38 products:
Human Polyclonal CHRNB3 Primary Antibody für ELISA, WB - ABIN409076
Zeiger, Haberstick, Schlaepfer, Collins, Corley, Crowley, Hewitt, Hopfer, Lessem, McQueen, Rhee, Ehringer: The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco. in Human molecular genetics 2008
To gain a better understanding of the pathological processes underlying ND and ND-related behaviors and to promote the development of effective smoking cessation therapies, we here present the most recent studies concerning the genetic effects of the CHRNB3-CHRNA6 gene cluster in ND.
More low frequency variants in the CHRNA6/CHRNB3 gene region were observed in cases compared to controls.
the CHRNB3-A6 locus contains multiple variants affecting risk for vulnerability to cocaine and nicotine dependence as well as bipolar disorder, suggesting that they have pleiotropic effects.
Polymorphism in CHRNB3 gene is associated with esophageal adenocarcinoma.
The common variant rs13273442 in the CHRNB3-CHNRA6 (zeige CHRNA6 Antikörper) region is associated significantly with nicotine dependence in European Americans and African Americans.
CHRNB3 c.-57A>G alteration affects the promoter activity and is associated with Parkinson's disease (PD), and smoking in PD patients.
Level of cigarettes per day during adolescence and young adulthood is associated with CHRNB3A6, CHRNA5A3B4, and CHRNA2 (zeige CHRNA2 Antikörper)
Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence.
this study provides convincing evidence for a role of CHRNB3 in Nicotine Dependence.
these results demonstrate that the combined effect of rs6474412-C/T polymorphism in smoking-related CHRNB3-CHRNA6 region gene and smoking behavior may not confer risk to psoriasis vulgaris (PV), but may have impact on PV severity in Chinese Han population.
Chimeric nicotinic acetylcholine receptors reveal the roles for N-terminal extracellular domains of (nAChR (zeige CHRNA4 Antikörper)) beta3 subunits in the receptor activity and function.
beta3 subunit coexpression promotes function of alpha6*-nAChR (zeige CHRNA6 Antikörper)
Data show that in Prkce (zeige PRKCE Antikörper)(-/-) mice, conditioned place preference and self-administer behaviors are associated with reduced levels of alpha(6) and beta(3) nicotinic receptor subunit mRNA in the ventral midbrain and striatum.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997
acetylcholine receptor, neuronal nicotinic, beta-3 subunit
, acetylcholine receptor, nicotinic, beta 3 (neuronal)
, cholinergic receptor, nicotinic, beta polypeptide 3
, neuronal acetylcholine receptor subunit beta-3
, cholinergic receptor, nicotinic, beta 3
, neuronal acetylcholine receptor subunit beta-3-like
, cholinergic receptor neuronal nicotinic beta protein 3
, nicotinic acetylcholine receptor beta 3 subunit