anti-Chemokine (C-C Motif) Receptor 8 (CCR8) Antikörper

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Zusätzlich bieten wir Ihnen CCR8 Kits (19) und CCR8 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CCR8 1237 P51685
CCR8 12776 P56484
CCR8 301066  
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Top anti-CCR8 Antikörper auf antikoerper-online.de

Showing 10 out of 115 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CCR8 Antibody Titration:  2.5ug/ml  Positive Control:  K562 cell lysate CCR8 is supported by BioGPS gene expression data to be expressed in K562 100 μL 2 bis 3 Tage
$249.00
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB CCR8 Antibody (C-term) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CCR8 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CCR8 antibody detected the CCR8 protein (arrow). 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image CCR8 antibody detects CCR8 protein at membrane on A549 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded A549 xenograft. CCR8 antibody , dilution: 1:500. 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: K562 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image CCR8 antibody detects CCR8 protein at membrane on human gastric cancer by immunohistochemical analysis. Sample: Paraffin-embedded gastric cancer. CCR8 antibody , dilution: 1:500. 100 μL 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-CCR8 antibody  ABIN1048403 IHC staining of human tonsil, germinal center and mantle zone. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CCR8 antibody IHC of human tonsil, germinal center and mantle zone. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-CCR8 antibody  ABIN1048404 IHC staining of human tonsil, germinal center. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CCR8 antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) Human Tonsil (formalin-fixed, paraffin-embedded) stained with CCR8 antibody ABIN213445 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-CCR8 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of CCR8 using COLO205 whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$537.17
Details

Am meisten referenzierte anti-CCR8 Antikörper

  1. Human Polyclonal CCR8 Primary Antibody für ELISA, WB - ABIN1002066 : Zaballos, Varona, Gutiérrez, Lind, Márquez: Molecular cloning and RNA expression of two new human chemokine receptor-like genes. in Biochemical and biophysical research communications 1996 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal CCR8 Primary Antibody für FACS - ABIN4895444 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Polyclonal CCR8 Primary Antibody für IHC (p), IHC - ABIN152132 : Liu, Cao, Tang, Liu, Tang: CCR7, CCR8, CCR9 and CCR10 in the mouse hippocampal CA1 area and the dentate gyrus during and after pilocarpine-induced status epilepticus. in Journal of neurochemistry 2007 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal CCR8 Primary Antibody für FACS - ABIN4895440 : Ahern, Lloyd, Robinson: Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors. in Allergy 2009 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal CCR8 Primary Antibody für IHC (p) - ABIN270974 : Brix, Stege, Disteldorf, Hoxha, Krebs, Krohn, Otto, Klätschke, Herden, Heymann, Lira, Tacke, Wolf, Busch, Jabs, Özcan, Keller, Beige, Wagner, Helmchen, Noriega, Wiech, Panzer, Stahl: CC Chemokine Ligand 18 in ANCA-Associated Crescentic GN. in Journal of the American Society of Nephrology : JASN 2015 (PubMed)

  6. Human Polyclonal CCR8 Primary Antibody für IHC (p) - ABIN4289263 : Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

Weitere Antikörper gegen CCR8 Interaktionspartner

Human Chemokine (C-C Motif) Receptor 8 (CCR8) Interaktionspartner

  1. Blocking CCR8 via a small molecule inhibitor or short hairpin (sh)RNA mitigated the decrease in Ecadherin, and increase in MMP2 and VEGFC, caused by human recombinant (r)CCL18. CCR8 knockdown by shRNA reversed rCCL18induced cancer cell invasion, migration and epithelialmesenchymal transition

  2. Long-lived memory T cells in human skin can be defined by the expression of CCR8.

  3. Authors demonstrate the pivotal role of CCR8(+) Treg cells in restraining immunity and highlight the potential clinical implications of this discovery.

  4. Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding.

  5. High CCR8 expression is associated with high recurrence in kidney cancer.

  6. findings suggest that CCR8 expression in ALCL is more closely related to the presence of DUSP22 rearrangements than to cutaneous involvement and that the function of CCR8 may extend beyond its skin-homing properties in this disease

  7. Epidermal-derived vitamin D3 metabolites and prostaglandins provide an essential cue for the localization of CCR8+ immune surveillance T cells within healthy human skin.

  8. CCL1-CCR8 interaction may play a critical role in lymphocytic recruitment in IgG4-related sclerosing cholangitis and type 1 autoimmune pancreatitis, leading to duct-centred inflammation and obliterative phlebitis.

  9. Identification of human CCR8 as a CCL18 receptor.

  10. CCR8(+) myeloid cell subset is expanded in patients with cancer.

  11. Data show that CCR8 expression by newly activated naive T cells is regulated by skin-specific factor(s) derived primarily from epidermal keratinocytes.

  12. C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  13. The functional data from human macrophages suggest a potential cross talk between the CCR8 and the Toll-like receptor 4 (TLR4) pathways, both of which are present in chronic obstructive pulmonary disease patients.

  14. There may be a role for CCR8 in the recruitment of T cells to the lung in asthmatics.

  15. CCR8 mediates rescue from dexamethasone-induced apoptosis via an ERK-dependent pathway

  16. found in the central nervous system and is associated with phagocytic macrophages

  17. CCR8 genes and surrounding genomic regions these genes are the result of the duplication of an ancestral gene prior to the divergence of teleost fish.

  18. Transfected human CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I.

  19. The induction of CCR8 under conditions associated with vascular smooth muscle cell proliferation and migration raises the possibility that CCR8 may play an important role in vessel wall pathology.

  20. the axis CCL1-CCR8 links adaptive and innate immune functions that play a role in the initiation and amplification of atopic skin inflammation

Mouse (Murine) Chemokine (C-C Motif) Receptor 8 (CCR8) Interaktionspartner

  1. this study shows that the chemokine receptor CCR8 promotes the migration of dendritic cells into the lymph node parenchyma to initiate the allergic immune response

  2. CCR8 negatively regulates migration of cutaneous dendritic cells from the skin to the draining lymph nodes in contact hypersensitivity by keeping these cells in the skin.

  3. Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages.

  4. A sustained donor Treg presence is critical for their beneficial properties, and that their survival depends on CCR8 and donor but not host CD11c(+) Aantigen presenting cells.

  5. Expression of CCR-8 in microglia was upregulated in the presence of CCL-1.

  6. C-terminal clipping of chemokine CCL1/I-309 enhances CCR8-mediated intracellular calcium release and anti-apoptotic activity

  7. Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice.

  8. a key regulator of Th2 cell skin recruitment during IL-5-mediated allergic inflammation

  9. mediates increased responsiveness of murine eosinophils to TCA-3

  10. Data from three different models plus an in vivo blocking study clearly show that the Th2 cell-mediated pathological response to ovalbumin-induced allergic airway inflammation is not critically CCR8-dependent.

  11. sulfation at specific positions of the N-terminal domain of mouse CCR8 is critical for its biological activity, whereas glycosylation has a minor influence

  12. IL-10 production correlates with CCR8 ligand (CCL1) expression and the appearance of CCR8+ cells in granulomatous lungs and is required for full expression of the T helper type 2 cell response to parasite antigens.

  13. CCR8 may have a negative impact on host defense during septic peritonitis, providing a new paradigm for the role of CCR8 in innate immunity.

  14. CCR8 ligands are allotropic, binding to distinct sites within CCR8

  15. CCR8 is expressed by a small and heterogeneous population of peripheral blood CD4 memory T cells enriched in T helper type 2 (Th2) effector and T regulatory (Treg) cells.

  16. Ccr8 has a pivotal role in the progression of experimental fungal asthma.

  17. Mast cell-derived CCR8- and CCL1-expressing CD4-positive effector T lymphocytes play an essential role in orchestrating lung mucosal inflammatory responses.

  18. Results suggest that CCR8 plays a significant role in the pathogenesis of experimental autoimmune encephalomyelitis and probalby of multiple sclerosis.

  19. CCR8/CCL1 interaction may play a role in type 1 diabetes through macrophage recruitment and activation

  20. Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.

CCR8 Antigen-Profil

Protein Überblick

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.

Genbezeichner und Symbole assoziert mit CCR8

  • C-C motif chemokine receptor 8 (CCR8) Antikörper
  • chemokine (C-C motif) receptor 8 (Ccr8) Antikörper
  • C-C motif chemokine receptor 8 (Ccr8) Antikörper
  • C-C Antikörper
  • C-C CKR-8 Antikörper
  • CC-CKR-8 Antikörper
  • CCR-8 Antikörper
  • CDw198 Antikörper
  • CKR-8 Antikörper
  • CKRL1 Antikörper
  • Cmkbr8 Antikörper
  • CMKBRL2 Antikörper
  • CY6 Antikörper
  • GPRCY6 Antikörper
  • mCCR8 Antikörper
  • TER1 Antikörper

Bezeichner auf Proteinebene für CCR8

C-C chemokine receptor type 8 , CC chemokine receptor 8 , CC chemokine receptor CHEMR1 , CC-chemokine receptor chemr1 , chemokine (C-C) receptor 8 , chemokine (C-C) receptor-like 2 , chemokine receptor-like 1 , C-C motif chemokine receptor 8

GENE ID SPEZIES
1237 Homo sapiens
12776 Mus musculus
693806 Macaca mulatta
301066 Rattus norvegicus
420718 Gallus gallus
407772 Bos taurus
100345500 Oryctolagus cuniculus
100725278 Cavia porcellus
Ausgewählte Anbieter für anti-CCR8 (CCR8) Antikörper
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