anti-Chemokine (C-C Motif) Receptor 1 (CCR1) Antikörper

CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Zusätzlich bieten wir Ihnen CCR1 Kits (32) und CCR1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CCR1 1230 P32246
CCR1 12768 P51675
CCR1 57301  
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Top anti-CCR1 Antikörper auf antikoerper-online.de

Showing 10 out of 188 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus PE FACS Detection of CCR1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Maus Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of CCR1 using anti- CCR1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each Lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat brain tissue lysates, Lane 2: mouse brain tissue lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- CCR1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CCR1 at approximately 41KD. The expected band size for CCR1 is at 41KD. IHC analysis of CCR1 using anti- CCR1 antibody . CCR1 was detected in paraffin-embedded section of mouse lymphaden tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- CCR1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert WB Western blot analsysis of CCR1 in Jurkat cell lysate. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$280.00
Details
Human Kaninchen Unkonjugiert FACS, ICC, IF, IHC (p), WB Immunohistochemistry-Paraffin: CCR1 Antibody [ABIN42889164] - Formalin-fixed, paraffin-embedded normal human spleen tissue stained with CCR1 antibody (5 ug/ml), peroxidase-conjugate and DAB chromogen. Note granulocyte staining. Flow Cytometry: CCR1 Antibody [ABIN42889164] - Image 1: Surface staining of mouse primary epidermal cells (B-6 mice, 30wks) with CL 11-PE, CD11c PE-Cy5, and CCR1 (Langerans), stained with rabbit isotype control (shaded histogram) were analyzed for CCR1 at 5ul (blue histogram) and 10ul (green histogram). Data kindly provided by Corey Parlet, University of Iowa. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: CCR1 Antibody [NBP2-31088] - Analysis of spleen (lymphocytes) using this antibody at 5 ug/ ml. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Analysis of anti-CCR1 antibody with skeletal muscle, myocytes. Immunohistochemistry-Paraffin: CCR1 Antibody [NLS1242] - Analysis of anti-CCR1 antibody with human colon, carcinoma. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Ratte Kaninchen Unkonjugiert WB Western blot analysis of CCR1 using anti-CCR1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each Lane was loaded with 50ug of sample under reducing conditions. Lane 1: rat PC-12 whole Cell lysate. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CCR1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CCR1 at approximately 48KD. The expected band size for CCR1 is at 41KD. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert CyTOF, FACS   100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$308.20
Details
Human Ziege Unkonjugiert ELISA, ICC, IHC, IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-CCR1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-CCR1 antibody ABIN1048386 IHC staining of human small intestine, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CCR1 antibody IHC of human small intestine, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details

Am meisten referenzierte anti-CCR1 Antikörper

  1. Human Monoclonal CCR1 Primary Antibody für FACS - ABIN4898192 : Broux, Mizee, Vanheusden, van der Pol, van Horssen, Van Wijmeersch, Somers, de Vries, Stinissen, Hellings: IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)
    Show all 19 Pubmed References

  2. Human Monoclonal CCR1 Primary Antibody für CyTOF, FACS - ABIN4900686 : Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 16 Pubmed References

  3. Human Polyclonal CCR1 Primary Antibody für FACS, ICC - ABIN4288916 : Demoule, Divangahi, Danialou, Gvozdic, Larkin, Bao, Petrof: Expression and regulation of CC class chemokines in the dystrophic (mdx) diaphragm. in American journal of respiratory cell and molecular biology 2005 (PubMed)
    Show all 6 Pubmed References

  4. Mouse (Murine) Monoclonal CCR1 Primary Antibody für CyTOF, FACS - ABIN4899318 : Baba, Naka, Morishita, Komatsu, Hirao, Mukaida: MIP-1α/CCL3-mediated maintenance of leukemia-initiating cells in the initiation process of chronic myeloid leukemia. in The Journal of experimental medicine 2013 (PubMed)
    Show all 2 Pubmed References

  5. Mouse (Murine) Monoclonal CCR1 Primary Antibody für FACS - ABIN4895914 : Sun, Chen, Lin, Chen, Yu, Hou, Li: Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain. in Molecular immunology 2016 (PubMed)

  6. Mouse (Murine) Monoclonal CCR1 Primary Antibody für FACS - ABIN4895916 : Fleming, Chandrasekaran, Dillon, Dalby, Suresh, Sarkar, El-Sayed, Mosser: The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. in Journal of leukocyte biology 2015 (PubMed)

  7. Human Monoclonal CCR1 Primary Antibody für FACS - ABIN4898187 : de la Rica, García-Gómez, Comet, Rodríguez-Ubreva, Ciudad, Vento-Tormo, Company, Álvarez-Errico, García, Gómez-Vaquero, Ballestar: NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation. in Genome biology 2015 (PubMed)

  8. Mouse (Murine) Polyclonal CCR1 Primary Antibody für ELISA - ABIN4258851 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)

  9. Human Polyclonal CCR1 Primary Antibody für IHC, IHC (p) - ABIN4288932 : Pacheco-Rodriguez, Kumaki, Steagall, Zhang, Ikeda, Lin, Billings, Moss: Chemokine-enhanced chemotaxis of lymphangioleiomyomatosis cells with mutations in the tumor suppressor TSC2 gene. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

Weitere Antikörper gegen CCR1 Interaktionspartner

Human Chemokine (C-C Motif) Receptor 1 (CCR1) Interaktionspartner

  1. Data suggest that CCR1 gene may be a putative marker of molecular activity of Crohn's disease.

  2. Results reveal that CCR1 expression is positively correlated with OPN (zeige SPP1 Antikörper) expression in hepatocellular carcinoma cells, and the patients with high levels of both OPN (zeige SPP1 Antikörper) and CCR1 have the most dismal prognosis. Study also, shows that steopontin upregulates CCR1 in HCC (zeige FAM126A Antikörper) cells and, that CCR1 is essential for osteopontin (zeige SPP1 Antikörper)-induced HCC (zeige FAM126A Antikörper) metastasis.

  3. Expression of CCR1 was measured in retrospective clinical specimens of colorectal cancer lung metastases. CCR1+ cells accumulated around the CCL15 (zeige CCL15 Antikörper)-positive colorectal cancer cells in the lung, but few around the CCL15 (zeige CCL15 Antikörper)-negative ones.

  4. during renal transplantation, CD4+ and CD8+ T cells expressing CCR1 were increased in patients who developed renal allograft dysfunction

  5. MIP-1alpha (zeige CCL3 Antikörper) receptor antagonism can significantly reduce T cell migration to the secreted factors from Oesophagogastric adenocarcinoma omentum and liver.

  6. These data suggest that CCR1/CCR2B (zeige CCR2 Antikörper) could be involved in clearing EBV-infected latency III B cells in immunocompetent individuals via directing the migration of these cells and attracting the chemokines-expressing immune cells.

  7. Data suggest that the interplay between CCR1 upregulation and inactivation of CXCR4 (zeige CXCR4 Antikörper) signaling (the CCR1/CXCR4 (zeige CXCR4 Antikörper) axis) drives the egress of multiple myeloma PCs from the bone marrow, leading to disease dissemination.

  8. Basophil migration into skin lesions of Systemic Lupus Erythematosus patients were observed, but not in normal skin tissue. This migration was related to the upregulation of chemokine receptors CCR1 and CCR2 on basophils.

  9. Study indicates that two distinct micro-environmental factors, CD40L (zeige CD40LG Antikörper) and Mphis, signal via CCR1 to induce AKT (zeige AKT1 Antikörper) activation resulting in translational stabilization of MCL-1 (zeige MCL1 Antikörper), and hence can contribute to CLL cell survival.

  10. CCL15 activation of CCR1 plays critical roles in hepatocellular carcinoma metastasis.

Mouse (Murine) Chemokine (C-C Motif) Receptor 1 (CCR1) Interaktionspartner

  1. The enhanced presence of CCL3 can explain the immediate analgesic effects, independent from an anti-inflammatory action, evoked by the administration of the CCR1 antagonist J113863 in carrageenan- and complete Freund's adjuvant inflamed mice.

  2. Inhibition of CCR1, the distal part of this signaling relay, may have a therapeutic impact in metastatic disease with lower toxicity than blocking upstream targets.

  3. Data indicate that deletion or inhibition of CC chemokine receptor 1 (CCR1) decreases pain responses.

  4. CCR1-mediated accumulation of myeloid cells in the liver microenvironment promotes mouse colon cancer metastasis.

  5. CCR1 is required for recruitment of neutrophils during respiratory infection with modified vaccinia virus Ankara.

  6. This study demonstrates a Tpl2 (zeige MAP3K8 Antikörper)-dependent mechanism for macrophage expression of select chemokine (zeige CCL1 Antikörper) receptors.

  7. Ccr1 plays a critical role in the recruitment of T and mononuclear phagocyte cells to inflamed kidneys of NZB/W mice, which in turn contribute to the progression of renal injury.

  8. CCR1.beta-arrestin-2 (zeige ARRB2 Antikörper) complex may be related to a potential scavenging function of the receptor, which may be important for maintenance of chemokine (zeige CCL1 Antikörper) gradients and receptor responsiveness in complex fields of chemokines during inflammation.

  9. CCR1 expression by both hematopoietic and nonhematopoietic cells favors tumor aggressiveness and liver cancer metastasis development.

  10. findings show that CCR1 is pivotal for bone remodeling induced by mechanical loading during orthodontic tooth movement and these actions depend, at least in part, on CCL3 (zeige CCL3 Antikörper)

CCR1 Antigen-Profil

Protein Überblick

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

Genbezeichner und Symbole assoziert mit CCR1

  • C-C motif chemokine receptor 1 (CCR1) Antikörper
  • chemokine (C-C motif) receptor 1 (Ccr1) Antikörper
  • C-C motif chemokine receptor 1 (Ccr1) Antikörper
  • CD191 Antikörper
  • CKR-1 Antikörper
  • CKR1 Antikörper
  • Cmkbr1 Antikörper
  • HM145 Antikörper
  • Mip-1a-R Antikörper
  • MIP1aR Antikörper
  • SCYAR1 Antikörper

Bezeichner auf Proteinebene für CCR1

C-C CKR-1 , C-C chemokine receptor type 1 , CC-CKR-1 , CCR-1 , LD78 receptor , MIP-1alpha-R , RANTES receptor , RANTES-R , macrophage inflammatory protein 1-alpha receptor , MIP-1 alpha R , MIP-1 alphaR , chemokine (C-C) receptor 1 , macrophage inflammatory protein-1 alpha receptor , chemokine receptor

GENE ID SPEZIES
1230 Homo sapiens
12768 Mus musculus
57301 Rattus norvegicus
574188 Macaca mulatta
Ausgewählte Anbieter für anti-CCR1 (CCR1) Antikörper
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