anti-Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Antikörper

human homolog may play a role in regulation of transcription and splicing. Zusätzlich bieten wir Ihnen Cdc2-Related Kinase, Arginine/serine-Rich Kits (11) und Cdc2-Related Kinase, Arginine/serine-Rich Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CRKRS 51755 Q9NYV4
CRKRS 69131 Q14AX6
CRKRS 192350 Q3MJK5
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Top anti-Cdc2-Related Kinase, Arginine/serine-Rich Antikörper auf antikoerper-online.de

Showing 10 out of 43 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB The anti-CRK7 Pab (ABIN391769) is used in Western blot to detect CRK1 in mouse liver tissue lysate. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Hund Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: CrkRS Antibody [NLS7350] - Analysis of anti-CDK12 / CRKRS antibody with human breast carcinoma at 6 ug/ml. Immunohistochemistry-Paraffin: CrkRS Antibody  - Anti-CDK12 / CRKRS antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot: CrkRS Antibody  - Detection of Human and Mouse CrkRS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-CrkRS antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Hund Kaninchen Unkonjugiert IHC, IHC (p) Anti-CDK12 / CRKRS antibody  ABIN1048422 IHC staining of human breast carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-CDK12 / CRKRS antibody  ABIN1048421 IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, WB The anti-CRK7 Pab is used in Western blot to detect CRK1 in mouse liver tissue lysate. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to CRKRS on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml] Immunofluorescence of monoclonal antibody to CRKRS on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: CrkRS Antibody [NBP1-85451] - Staining of human pancreas shows strong nuclear positivity in exocrine glandular cells and islet cells. Immunocytochemistry/Immunofluorescence: CrkRS Antibody [NBP1-85451] Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Maus Unkonjugiert ELISA, WB CRKRS monoclonal antibody (M02A), clone 2F6 Western Blot analysis of CRKRS expression in Hela S3 NE . Western Blot detection against Immunogen (36.63 KDa) . 200 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

CRKRS Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Cdc2-Related Kinase, Arginine/serine-Rich Antikörper

  1. Human Polyclonal CRKRS Primary Antibody für IP, WB - ABIN257745 : Eifler, Shao, Bartholomeeusen, Fujinaga, Jäger, Johnson, Luo, Krogan, Peterlin: Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. in Molecular and cellular biology 2014 (PubMed)
    Show all 2 Pubmed References

  2. Dog (Canine) Polyclonal CRKRS Primary Antibody für IHC (p) - ABIN271286 : Capra, Nuciforo, Confalonieri, Quarto, Bianchi, Nebuloni, Boldorini, Pallotti, Viale, Gishizky, Draetta, Di Fiore: Frequent alterations in the expression of serine/threonine kinases in human cancers. in Cancer research 2006 (PubMed)

Weitere Antikörper gegen Cdc2-Related Kinase, Arginine/serine-Rich Interaktionspartner

Fruit Fly (Drosophila melanogaster) Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. Cdk12 suppresses genes that support metabolic functions in stressed conditions. Cdk12 is not a generally essential Pol II kinase and is not required for the transcription of essential and housekeeping genes at least in adult tissues.

  2. CDK12 plays a role in controlling the epigenetic transition between euchromatin and heterochromatin, suggesting a chromatin regulatory mechanism in neuronal behaviors.

  3. The phosphorylation of the C-terminal domain of the RNA polymerase II by Cdk12 provides an elegant mechanism in regulating timed splicing of newly synthesized mRNA molecules.

Human Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. CDK12 gene amplification can contribute to the pathogenesis of breast cancer.

  2. BRCA1 downregulation combined with CHK1 (zeige CHEK1 Antikörper) inhibition induced excessive amounts of DNA damage, resulting in an inability to complete the S-phase. Therefore, we suggest CHK1 (zeige CHEK1 Antikörper) inhibition as a strategy for targeting BRCA1- or CDK12-deficient tumors.

  3. In Ovarian Cancer patients CDK12 loss is consistently associated with a particular genomic instability pattern characterized by hundreds of tandem duplications

  4. Structures of CDK12/CycK (zeige CCNK Antikörper) complexes solved in the presence of AMP (zeige APRT Antikörper)-PNP (zeige NP Antikörper).

  5. Data show that most mutations prevent formation of the cyclin-dependent kinase 12 (Cdk12)/cyclin K (CycK (zeige CCNK Antikörper)) complex, rendering the kinase inactive.

  6. CDK12 affects RNA processing events in two distinct ways: Indirectly through generating factor-binding phospho-epitopes on the CTD of elongating RNAPII (zeige 0 Antikörper) and directly through binding to specific factors

  7. CDK12 and CDK13 (zeige CDK13 Antikörper) losses in HCT116 cells preferentially affect expression of DNA damage response.

  8. CDK12 plays an important role in cotranscriptional processing of c-FOS transcripts

  9. CDK12 has properties that should confirm interest in its use as a biomarker.

  10. many CDK12 mutations are an unrecognized cause of HR defects in ovarian cancers

Mouse (Murine) Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Interaktionspartner

  1. Spontaneous DNA damage was revealed by an increase in 53BP1 (zeige TP53BP1 Antikörper) foci among cells cultured from Cdk12(-/-) embryos.

  2. Report on the functions of Cdk12 during neural development in vivo, proposes a dual role for Cdk12 in neurogenesis and late stage neuronal migration via 2 distinct pathways

  3. The findings of this study suggest that Cdk12 and Cdk13 (zeige CDK13 Antikörper) regulate axonal elongation through a common signaling pathway that modulates Cdk5 (zeige CDK5 Antikörper) expression.

Cdc2-Related Kinase, Arginine/serine-Rich (CRKRS) Antigen-Profil

Protein Überblick

human homolog may play a role in regulation of transcription and splicing

Genbezeichner und Symbole assoziert mit CRKRS

  • Cyclin-dependent kinase 12 (Cdk12) Antikörper
  • cyclin dependent kinase 12 (CDK12) Antikörper
  • cyclin-dependent kinase 12 (Cdk12) Antikörper
  • 1810022J16Rik Antikörper
  • AC017581 Antikörper
  • AI646528 Antikörper
  • anon-WO0140519.165 Antikörper
  • cg7597 Antikörper
  • Crk7 Antikörper
  • CRKR Antikörper
  • Crkrs Antikörper
  • D11Ertd752e Antikörper
  • dCDK12 Antikörper
  • Dmel\\CG7597 Antikörper
  • gi24668141 Antikörper
  • hCDK12 Antikörper
  • Pksc Antikörper

Bezeichner auf Proteinebene für CRKRS

CG7597-PA , CG7597-PB , CG7597-PC , Cdk12-PA , Cdk12-PB , Cdk12-PC , Cdc2-related kinase, arginine/serine-rich , CDC2-related protein kinase 7 , cell division cycle 2-related protein kinase 7 , cell division protein kinase 12 , CDC2-related kinase 7 , CDC2-related kinase, arginine/serine-rich , protein kinase for splicing component , cyclin-dependent kinase 12 isoform , cyclin-dependent kinase 12 , Cell division protein kinase 12

GENE ID SPEZIES
40385 Drosophila melanogaster
100354313 Oryctolagus cuniculus
51755 Homo sapiens
69131 Mus musculus
192350 Rattus norvegicus
511513 Bos taurus
100467815 Ailuropoda melanoleuca
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