anti-Cathepsin A (CTSA) Antikörper

CTSA encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. Zusätzlich bieten wir Ihnen Cathepsin A Proteine (29) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CTSA 296370  
CTSA 5476 P10619
CTSA 19025 P16675
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Top anti-Cathepsin A Antikörper auf antikoerper-online.de

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB CTSA Antibody (N-term)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CTSA antibody detected the CTSA protein (arrow). CTSA Antibody (N-term)  western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the CTSA antibody detected the CTSA protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Cathepsin A Antibody [NBP1-89728] - Staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Immunohistochemistry-Paraffin: Cathepsin A/Lysosomal Carboxypeptidase A Antibody [NBP1-89728] - Staining of human kidney shows strong cytoplasmic positivity in renal tubules. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from 293/Jurkat cells, treated with etoposide 25uM 1h, using PPGB (32k,Cleaved-Arg326) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB CTSA antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CTSA antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. CTSA Antibody (N-term) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the CTSA antibody detected the CTSA protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, IF/ICC Immunofluorescence staining of Human CTSA in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CTSA monoclonal antibody (15 µg/ml) at 4℃ overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm. 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$273.90
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB DAB staining on IHC-P; Samples: Human Colorectal cancer Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$316.00
Details
Maus Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin- embedded kidney tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$324.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$342.00
Details
Hund Kaninchen Unkonjugiert ICC, IHC, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$360.00
Details
Wildschwein Kaninchen Unkonjugiert ICC, IHC, WB 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$378.00
Details

Am meisten referenzierte anti-Cathepsin A Antikörper

  1. Human Polyclonal CTSA Primary Antibody für IHC (p), WB - ABIN654433 : Hossain, Higaki, Shinpo, Nanba, Suzuki, Ozono, Sakai: Chemical chaperone treatment for galactosialidosis: Effect of NOEV on ?-galactosidase activities in fibroblasts. in Brain & development 2015 (PubMed)

Weitere Antikörper gegen Cathepsin A Interaktionspartner

Arabidopsis thaliana Cathepsin A (CTSA) Interaktionspartner

  1. Studies indicate the transcript accumulation of the beta-galactosidases (BGAL (zeige GLB1 Antikörper)) genes AtBGAL1 (At3g13750), AtBGAL2 (At3g52840), AtBGAL3 (At4g36360), AtBGAL4 (At5g56870), AtBGAL5 (At1g45130) and AtBGAL12 (At4g26140) along the plant development, as well as their subcellular location by the construction of transgenic plants producing the enhanced green fluorescent protein (eGFP) fused to the six BGAL (zeige GLB1 Antikörper) proteins.

  2. It is shown by dot-immunoblotting that At3g52840 is the gene expressing Gal-2 (zeige LGALS2 Antikörper) which is associated with the cell wall in Arabidopsis.

Human Cathepsin A (CTSA) Interaktionspartner

  1. The usefulness of modified U1 snRNA for rescue from exon 7 skipping caused by the IVS7 +3a>g mutation of the CTSA gene.

  2. The gene signature of OPA1 (zeige OPA1 Antikörper), CTSA, NDUFA1 (zeige NDUFA1 Antikörper), STK10 and PRDX1 (zeige PRDX1 Antikörper) was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls.

  3. Galactosialidosis is a rare lysosomal storage disease caused by a combined deficiency of GM1 beta-galactosidase (beta-gal (zeige GLB1 Antikörper)) and neuraminidase (zeige NA Antikörper) secondary to a defect of a lysosomal enzyme protective protein/cathepsin A (PPCA) and mutation in CTSA gene.

  4. Case Report: galactosialidosis with novel mutations of CTSA gene diagnosed using placental pathology.

  5. We identified compound heterozygous mutations in the CTSA gene, responsible for causing galactosialidosis

  6. correct nomenclature of mutations for this gene is discussed; clinical and mutational analyses of 4 cases with rare infantile form of galactosialidosis; identified 3 novel nucleotide changes, 2 resulting in missense mutations and the third, resulting in the p.Gln406* stop codon; complexity of the clinical phenotypes in GS reflects dual functions of PPCA/CTSA

  7. Catalytic function, tissue distribution and substrates of cathepsin A are discussed as well as inhibition of cathepsin A as an emerging strategy for the treatment of heart failure.

  8. The Cathepsin C (zeige CTSC Antikörper) releases the glycosidases from complexes formed with cathepsin A, and reinstates their activity.

  9. Our data suggest that CatA (zeige CAT Antikörper) is involved in the C-terminal fine-tuning of antigenic T cell epitopes in human APC (zeige APC Antikörper).

  10. Increased activity of beta-galactosidase (zeige GLB1 Antikörper) in the peritoneal fluid is associated with gynecologic cancers and pelvic inflammatory disease

Mouse (Murine) Cathepsin A (CTSA) Interaktionspartner

  1. in normal tissues the tandem of serine carboxypeptidases, Scpep1 (zeige SCPEP1 Antikörper) and CathA likely constitutes an important part of the physiological mechanism responsible for the balanced elimination of heightened levels of ET-1 (zeige EDN1 Antikörper) that otherwise would accumulate in tissues and consequently contribute to development of the hyper-proliferative corneal dystrophy and abnormal skin thickening

  2. our results define the biological role of mammalian serine carboxypeptidase Scpep1 (zeige SCPEP1 Antikörper) and suggest that Scpep1 (zeige SCPEP1 Antikörper) and CathA together participate in the control of ET-1 (zeige EDN1 Antikörper) regulation of vascular tone and hemodynamics

  3. Loss of the cathepsin A results in the lysosomal storage disease galactosialidosis. However, mice with a catalytically inactive cathepsin A enzyme show no signs of this disease.

  4. characterization of human PPCA, including N-terminal sequencing of the two cleavage products

  5. the compromised halo cells, due to PPCA deficiency within their lysosomes, cannot function properly and as a result there is a recruitment of macrophages in the intertubular space

  6. PPCA deficiency causes structural changes to the blood-epididymal barrier as evidenced by lanthanum nitrate and Cldns expression that affects the luminal environment of the epididymis, resulting in altered sperm motility.

  7. CathA acts in vivo as an endothelin-1 (zeige EDN1 Antikörper)-inactivating enzyme and strongly confirm a crucial role of this enzyme in effective elastic fiber formation.

  8. Results indicate a novel role for PPCA/cathepsin A in osteoclastogenesis via down-regulation of NF-kappaB p50 (zeige NFKB1 Antikörper)/p65 (zeige NFkBP65 Antikörper) activity and suggest a new function for PPCA as an NF-kappaB (zeige NFKB1 Antikörper)-degrading enzyme in addition to its known multifunctional properties.

  9. Results describe the hydrodynamic properties of PPCA, NEU1 (zeige NEURL Antikörper), and a complex of the two proteins and identified multiple binding sites on both proteins.

  10. The N-terminal N-glycan of NEU1 (zeige NEURL Antikörper) is indispensable for its function, whereas the C-terminal N-glycan appears to be non-essential. The omission of the second N-glycan can be compensated for by upregulating the expression of PPCA

Cow (Bovine) Cathepsin A (CTSA) Interaktionspartner

  1. PPGB gene is not responsible for the lysosomal storage disease of Japanese Black cattle.

Cathepsin A (CTSA) Antigen-Profil

Protein Überblick

This gene encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Cathepsin A (CTSA) Antikörper

  • cathepsin A (Ctsa) Antikörper
  • beta-galactosidase 2 (BGAL2) Antikörper
  • cathepsin A (CTSA) Antikörper
  • AU019505 Antikörper
  • beta-galactosidase 2 Antikörper
  • GLB2 Antikörper
  • GSL Antikörper
  • NGBE Antikörper
  • PPCA Antikörper
  • PPGB Antikörper

Bezeichner auf Proteinebene für anti-Cathepsin A (CTSA) Antikörper

lysosomal protective protein , protective protein for beta-galactosidase , protective protein for beta-galactosidase (galactosialidosis) , beta-galactosidase 2 , beta-galactosidase protective protein , carboxypeptidase C , carboxypeptidase L , carboxypeptidase Y-like kininase , carboxypeptidase-L , deamidase , lysosomal carboxypeptidase A , protective protein cathepsin A , urinary kininase

GENE ID SPEZIES
296370 Rattus norvegicus
824450 Arabidopsis thaliana
428163 Gallus gallus
5476 Homo sapiens
19025 Mus musculus
518169 Bos taurus
100156798 Sus scrofa
611146 Canis lupus familiaris
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