anti-B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) Antikörper

BCL11B encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Zusätzlich bieten wir Ihnen BCL11B Kits (8) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BCL11B 58208 Q99PV8
BCL11B 64919 Q9C0K0
BCL11B 314423  
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Top anti-BCL11B Antikörper auf

Showing 10 out of 61 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-BCL11B Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate BCL11B is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-BCL11B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: BCL11B Sample Type: 293T Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human cerebral cortex shows strong nuclear positivity in a subset of neurons. Immunocytochemistry/Immunofluorescence: BCL11B Antibody [NBP2-33549] - Staining of mouse parietal association cortex shows nuclear immunoreactivity in neurons. 0.1 mL Anmelden zum Anzeigen 34 Days
Human Kaninchen Unkonjugiert WB BCL11B Antibody (Center) (ABIN654919) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the BCL11B antibody detected the BCL11B protein (arrow). All lanes : Anti-BCL11B Antibody (Center) at 1:16000 dilution Lane 1: Jurkat whole cell lysate Lane 2: MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 96 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:16000 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Detection of Human Bcl11b by Western Blot and Immunoprecipitation. Samples: Nuclear extract (5 and 50 mcg for WB, 1 mg for IP) from Jurkat cells. Antibodies: ABIN153204 used at 0.1 mcg/ml (A) and 0.5 mcg/ml (B) for WB and at 1 and 10 mcg/mg lysate for IP (B). Bcl11b was also immunoprecipitated using affinity purified rabbit anti-Bcl11b antibodies ABIN153202 and ABIN153203 at 1 and 10 mcg/mg lysate. Normal rabbit IgG was used as a control for immunoprecipitation reactions. Detection: Chemiluminescence with exposure times of 1 minute (A), 1 second (B) or 30 seconds (B). Immunohistochemistry-Paraffin: BCL11B Antibody [ABIN153204] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert EIA, WB BCL11B Antibody (Center) western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the BCL11B antibody detected the BCL11B protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Maus Unkonjugiert ELISA, FACS, ICC, IF, IHC, WB ELISA: BCL11B Antibody (1F8G8)  - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Flow Cytometry: BCL11B Antibody (1F8G8)  - Analysis of Hela cells using BCL11B mouse mAb (green) and negative control (red). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p), WB Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-BCL11B antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other fo ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage

Am meisten referenzierte anti-BCL11B Antikörper

  1. Human Polyclonal BCL11B Primary Antibody für ICC, IF - ABIN251041 : Beguin, Crépel, Aniksztejn, Becq, Pelosi, Pallesi-Pocachard, Bouamrane, Pasqualetti, Kitamura, Cardoso, Represa: An epilepsy-related ARX polyalanine expansion modifies glutamatergic neurons excitability and morphology without affecting GABAergic neurons development. in Cerebral cortex (New York, N.Y. : 1991) 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal BCL11B Primary Antibody für ICC, IF - ABIN153204 : Matsumoto, Nagoshi, Yoshida, Kato, Kuroda, Shimura, Kaneko, Horiike, Nakamura, Taniwaki: Expression of Master Regulators of T-cell, Helper T-cell and Follicular Helper T-cell Differentiation in Angioimmunoblastic T-cell Lymphoma. in Internal medicine (Tokyo, Japan) 2018 (PubMed)

Weitere Antikörper gegen BCL11B Interaktionspartner

Mouse (Murine) B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) Interaktionspartner

  1. Mice lacking Bcl11b in mature T-cells have a diminished capacity to mount Th2 responses during helminth infection and allergic asthma, showing reduced Th2 cytokines and Gata3, and elevated Runx3.

  2. Thus, this study identifies BCL11B as a novel regulator of adipogenesis, which works, at least in part, by stimulating C/EBPbeta activity and suppressing the Wnt/beta-catenin signaling pathway.

  3. Bcl11b is associated with cell fate in the T-cell gene regulatory network.

  4. Bcl11b, known as a T-lineage commitment factor, is essential for proper expression of ThPOK and Runx3, central regulators for the CD4-helper/CD8-cytotoxic lineage choice.

  5. Authors provide insight into the mechanism that underpins the repositioning of regulatory elements; identify a non-coding RNA, named ThymoD, which acts to reposition the Bcl11 enhancer away from the lamina to the nuclear interior and sequester the Bcl11b promoter and enhancer region into a single-loop domain.

  6. key regulator of Invariant natural killer T-cell effector subsets, their function, identity, and survival

  7. these results suggest that Bcl11b acts as a central intrinsic regulator of mammary epithelial stem cell quiescence.

  8. BCL11B is expressed in both osteogenic and sutural mesenchyme of the developing craniofacial complex. Bcl11b(-/-) mice exhibit increased proliferation of osteoprogenitors, premature osteoblast differentiation, and enhanced skull mineralization leading to synostoses of facial and calvarial sutures.

  9. this study shows that distinct, asynchronous and stage-specific transcription factors (TCF-1, GATA-3 and Runx1) activate Bcl11b for T cell commitment

  10. the expression and function of Bcl11b in the oral epithelium and demonstration that Bcl11b is an essential regulator for keratinocyte differentiation and the morphogenesis of papillary structure of the lingual epithelium.

  11. BCL11B as a regulator of energy metabolism

  12. Data uncover for the first time a specific role of Bcl11b in adult hippocampal neurogenesis and function.

  13. BCL11B is extensively expressed in neocortical GABAergic interneurons of all three major subgroups and thus its expression is not restricted to subcerebral projections cells.

  14. Bcl11b regulates development of different thymocyte subsets at multiple stages and prevents an excess of innate CD8 single-positive thymocytes.

  15. sustains mature Type 2 innate lymphoid cells genetic and functional programs and lineage fidelity

  16. Data indicate kinetic changes in relative phosphorylation on 18 of 23 serine and threonine residues and sumoylation on one of two lysine resides in B-cell lymphoma-leukemia 11B protein BCL11B.

  17. BCL11B is expressed to potentially regulate the transition of mesenchymal differentiation and suture formation within craniofacial intramembranous bone.

  18. Bcl11b is essential for group 2 innate lymphoid cell development

  19. Bcl11b, a transcription factor essential in T cell lineage commitment and maintenance, is specifically expressed in progenitors committed to the ILC2 lineage and is required for ILC2 development

  20. Deletion junctions in Bcl11b exhibit greater germline nucleotide loss.

Human B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B) Interaktionspartner

  1. These results suggest that the upregulation of miR-650 contributes to the development of acute renal allograft rejection by suppression of BCL11B, which leads to apoptosis and inflammatory responses. Thus, miR-650 and BCL11B may represent potential therapeutic targets for the prevention of acute renal allograft rejection.

  2. In this present work, the authors identify and characterize a transcription factor i.e. HIC1, which physically interacts with both Bcl11b/CTIP2 and HMGA1 to co-regulate specific subsets of cellular genes and the HIV-1 tat gene.

  3. Decreased transcript and increased promoter methylation levels of BCL11B gene were identified in ankylosing spondylitis patients.

  4. this is the first study to show that the inhibition of Bcl11b suppresses glioma cell growth by regulating the expression of the cell cycle regulator p21 and stemness-associated genes (Sox-2/Bmi-1).

  5. studies show BCL11B is a key regulator of the initial stages of human T-cell differentiation and delineate the BCL11B transcriptional program, enabling the dissection of the underpinnings of normal T-cell differentiation and providing a resource for understanding dysregulations in T-ALL

  6. BCL11B showed increased but varied expression in advanced tumor stage. Analysis of four patients receiving SAHA treatment suggested a positive correlation between BCL11B expression and favorable response to SAHA treatment. In conclusion, BCL11B may serve as a therapeutic target and a useful marker for improving HDACi efficacy in advanced CTCL.

  7. Human T-cell leukemia virus type 1 (HTLV-1) Tax directly binds to BCL11B. Tax enhances BCL11B degradation through proteasome pathway. Loss of BCL11B enhances cell growth in HTLV-1-infected cells.

  8. Findings identify BCL11B Ser2 phosphorylation as a new mandatory step in the interconnected posttranslational modifications converting BCL11B from a transcriptional repressor to an activator.

  9. BCL11B introduction in human cell lines downregulated transcription of beta-catenin target genes, whereas Bcl11b attenuation in Lgr5(+) crypt base columnar cells increased expression of beta-catenin targets including c-Myc and cyclin D1.

  10. Tax is responsible for suppressing BCL11B protein expression in HTLV-1-infected T-cells; Tax-mediated repression of BCL11B is another mechanism that Tax uses to promote oncogenesis of HTLV-1-infected T-cells.

  11. low BCL11b expression was associated with poor prognosis; particularly in the standard risk group of thymic T-cell acute lymphoblastic leukemia

  12. Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations.

  13. a comprehensive review of the roles of Bcl11b in progenitors, effector T cells, regulatory T cells, and invariant NKT cells, as well as its impact on immune diseases.

  14. overexpressed in mycosis fungoides lesions

  15. CTIP2 controls P-TEFb function in physiological and pathological conditions.

  16. BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.

  17. a reduction in the level of the BCL11B protein is a key event in the multistep progression of ATLL leukemogenesis

  18. BLC11B is an oncogene in T-ALL pathogenesis.

  19. BCL11B gene silencing alone does not affect hematopoietic stem/progenitor cell proliferation and differentiation in vitro.

  20. REVIEW: describes phenotypes given by loss of Bcl11b and roles of Bcl11b in cell proliferation, differentiation and apoptosis, taking tissue development and lymphomagenesis into consideration

BCL11B Antigen-Profil

Protein Überblick

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

Genbezeichner und Symbole assoziert mit BCL11B

  • B-cell CLL/lymphoma 11B (BCL11B) Antikörper
  • B cell leukemia/lymphoma 11B (Bcl11b) Antikörper
  • B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B) Antikörper
  • B-cell CLL/lymphoma 11B (Bcl11b) Antikörper
  • 9130430L19Rik Antikörper
  • AI604821 Antikörper
  • ATL1 Antikörper
  • ATL1-alpha Antikörper
  • ATL1-beta Antikörper
  • ATL1-delta Antikörper
  • ATL1-gamma Antikörper
  • B630002E05Rik Antikörper
  • BCL-11B Antikörper
  • BCL11B Antikörper
  • CTIP-2 Antikörper
  • CTIP2 Antikörper
  • hRIT1-alpha Antikörper
  • RIT1 Antikörper
  • ZNF856B Antikörper

Bezeichner auf Proteinebene für BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein) , B-cell CLL/lymphoma 11B , B-cell CLL/lymphoma 11B, isoform 1 , B-cell leukemia/lymphoma 11B , B-cell lymphoma/leukaemia 11B , B-cell lymphoma/leukemia 11B , COUP-TF interacting protein 2 , COUP-TF-interacting protein 2 , mRit1 , radiation-induced tumor suppressor gene 1 protein , B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein , BCL-11B , BCL11B/TRDC fusion , hRit1 , zinc finger protein hRit1 alpha , B-cell lymphoma/leukemia 11B (predicted), 3 prime , B-cell lymphoma/leukemia 11B (predicted), 5 prime , COUP-TF-interacting protein 2 long form

423444 Gallus gallus
467548 Pan troglodytes
100137584 Papio anubis
58208 Mus musculus
64919 Homo sapiens
612476 Canis lupus familiaris
783269 Bos taurus
100328694 Oryctolagus cuniculus
314423 Rattus norvegicus
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