anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antikörper

ADH5 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Zusätzlich bieten wir Ihnen Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Proteine (31) und Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ADH5 128 P11766
ADH5 100145871 P12711
ADH5 11532 P28474
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Top anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antikörper auf antikoerper-online.de

Showing 10 out of 116 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Pferd Kaninchen Unkonjugiert WB WB Suggested Anti-ADH5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of ADH5 Antibody (Center) (ABIN652502) in K562 cell line lysates (35 µg/lane). ADH5 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADH5 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of ADH5 expression in rat brain extract ( Lane 1), mouse brain extract ( Lane 2) and HEPG2 whole cell lysates ( Lane 3). ADH5 at 40KD was detected using rabbit anti- ADH5 Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Rind (Kuh) Ziege Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$462.00
Details
Human Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of ADH5 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of ADH5 expression in U251 (A), U937 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
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Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of ADH5 Antibody (Center) in K562 cell line lysates (35ug/lane). ADH5 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IHC, WB Immunohistochemistry-Paraffin: alcohol dehydrogenase 5 Antibody (OTI5G4)  - Staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-ADH5 mouse monoclonal antibody.(Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 degrees C for 3 min, (1:150) Immunohistochemistry-Paraffin: alcohol dehydrogenase 5 Antibody (OTI5G4)  - Staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-ADH5 mouse monoclonal antibody. (Heatinduced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120 degrees C for 3 min, (1:150) 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IF, IHC, WB Immunofluorescence analysis of HepG2 cell using ADH5 antibody. Blue: DAPI for nuclear staining. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: alcohol dehydrogenase 5 Antibody [ABIN1887411] - (0.5ug/ml) staining of Human Testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details

ADH5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Antikörper

  1. Human Polyclonal ADH5 Primary Antibody für ELISA, WB - ABIN188741 : Adinolfi, Adinolfi, Hopkinson: Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme. in Annals of human genetics 1984 (PubMed)

Weitere Antikörper gegen Alcohol Dehydrogenase 5 (Class III), chi Polypeptide Interaktionspartner

Human Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Interaktionspartner

  1. Data (including data from studies using knockout and transgenic mice) suggest that obesity and diabetes are accompanied by decreases in GSNOR activity in hepatocytes engendering nitrosative stress; obesity promotes S-nitrosylation of lysosomal proteins in liver, thereby impairing lysosomal enzyme activities and compromising autophagy.

  2. GSNOR represents the prototype enzyme to disclose how denitrosylation plays a crucial role in tuning NO-bioactivity and how much it deeply impacts on cell homeostasis and human pathophysiology. (Review)

  3. It was concluded that in HepG2 cells, ADH5 is a source of formate for de novo purine biosynthesis, especially during folate deficiency when folate-dependent formate production is limited.

  4. GSNOR expression has different effect on neuronal viability in dependence on the stimulus applied, and plays opposite roles in SH-SY5Y models of Parkinson's disease and amyotrophic lateral sclerosis

  5. ADH5 counteracts neuronal differentiation of neural stem cells and this effect can be reversed by pharmacological inhibition of ADH5.

  6. common ADH (zeige AVP Antikörper) variants conferred risk for both schizophrenia in African-Americans and autism in European-Americans.

  7. A decrease in ADH (zeige AVP Antikörper) IB, rather than GSNOR, correlates with human lung cancer.

  8. study compared individuals occupationally exposed to formaldehyde and controls to effects of XRCC3 (zeige XRCC3 Antikörper) Thr241Met, ADH5 Val309Ile and Asp353Glu polymorphisms; ADH5 polymorphisms did not show significant association with genotoxicity biomarkers

  9. Data suggest that GSNOR deficiency, through dysregulated S-nitrosylation, may promote hepatocellular carcinoma, possibly by inactivating a DNA repair system.

  10. Significant associations were found however, for reactions to alcohol with a SNP in ADH5 (rs6827292, p = .001) and a SNP just upstream of ADH5 (rs6819724, p = .0007) that is in strong LD with rs6827292.

Mouse (Murine) Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Interaktionspartner

  1. Data (including data from studies using knockout and transgenic mice) suggest that obesity and diabetes are accompanied by decreases in GSNOR activity in hepatocytes engendering nitrosative stress; obesity promotes S-nitrosylation of lysosomal proteins in liver, thereby impairing lysosomal enzyme activities and compromising autophagy.

  2. Report inhibition of GSNOR activity by nebivolol leading to accumulation of nitrosothiols in cells, and this is associated with an enhanced vasodilation by S-nitrosoglutathione.

  3. Increased GSNOR expression during aging decreases S-nitrosation of CaMKIIalpha (zeige CAMK2 Antikörper) and reduces CaMKIIalpha (zeige CAMK2 Antikörper) synaptosomal accumulation.

  4. These data indicate a role for GSNOR in the host response to malaria infection and suggest that strategies to disrupt its activity will improve clinical outcomes.

  5. GSNOR may act as a "brake" on skeletal muscle contractile performance under physiological conditions by modulating nitrosylation/denitrosylation balance.

  6. Loss of GSNOR confers enhanced post-MI cardiac regenerative activity, characterized by enhanced turnover of cardiomyocytes and cardiac stem cells.

  7. Results show that ADH5 removes endogenous formaldehyde to prevent DNA adducts, and protects with FANCD2 (zeige FANCD2 Antikörper), hematopoietic stem cells, hepatocytes, and nephrons from endogenous DNA damage.

  8. S-nitrosoglutathione reductase-dependent modification of PPARgamma (zeige PPARG Antikörper) alters the balance between adipocyte and osteoblast differentiation and provides checkpoint regulation of the lineage bifurcation of these 2 lineages.

  9. These findings provide novel insights into the involvement of GSNOR and S-nitrosylation in neuromuscular atrophy and neuropathic pain that are associated with pathological states.

  10. Overexpression of ADH5 reduces both development and adult neuronal differentiation of neurons. This effect depends on the catalytic activity of ADH5 and involves ADH5-mediated denitrosation of histone deacetylase 2 (HDAC2 (zeige HDAC2 Antikörper)).

Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) Antigen-Profil

Protein Überblick

This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Genbezeichner und Symbole assoziert mit ADH5

  • alcohol dehydrogenase 5 (class III), chi polypeptide (ADH5) Antikörper
  • alcohol dehydrogenase 5 (adh5) Antikörper
  • alcohol dehydrogenase 5 (class III), chi polypeptide (Adh5) Antikörper
  • alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog (adh5.L) Antikörper
  • adh-3 Antikörper
  • Adh-5 Antikörper
  • ADH1C Antikörper
  • adh3 Antikörper
  • ADH4 Antikörper
  • adh5 Antikörper
  • adhx Antikörper
  • FALDH Antikörper
  • fdh Antikörper
  • GSH-FDH Antikörper
  • gsnor Antikörper
  • wu:fb60b11 Antikörper

Bezeichner auf Proteinebene für ADH5

S-(hydroxymethyl)glutathione dehydrogenase , alcohol dehydrogenase (class III), chi polypeptide , alcohol dehydrogenase class chi chain , alcohol dehydrogenase class-3 , alcohol dehydrogenase class-III , formaldehyde dehydrogenase , glutathione-dependent formaldehyde dehydrogenase , FALDH , FDH , GSH-FDH , alcohol dehydrogenase 1C (class I), gamma polypeptide , class III alcohol dehydrogenase , fb60b11 , ADH-B2 , alcohol dehydrogenase 2 , alcohol dehydrogenase B2 , class III alcohol dehydrogenase, chi subunit , S-nitrosoglutathione reductase , alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog , alcohol dehydrogenase class 3 , alcohol dehydrogenase 4 (class II), pi polypeptide

GENE ID SPEZIES
128 Homo sapiens
100009307 Oryctolagus cuniculus
116517 Danio rerio
100145871 Rattus norvegicus
11532 Mus musculus
505515 Bos taurus
100719427 Cavia porcellus
445841 Xenopus laevis
609781 Canis lupus familiaris
422705 Gallus gallus
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