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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation.
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These data suggest that MBD1 (zeige DPEP1 Antikörper).MCAF1 (zeige ATF7IP Antikörper).SETDB1 (zeige SETDB1 Antikörper) complex facilitates the formation of heterochromatic domains, emphasizing the role of MCAF (zeige CCL2 Antikörper)/AM family proteins in epigenetic control, and describe a new family member, MCAF2 (ATF7IP2).
cloning and characterization of PSM2; deduced protein has high similarity with human MCAF2; hypothesized that PSM2 might interact with some important partners by the conserved domain and be involved in the transcription modulation during gonad development
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity).
ATF7-interacting protein 2
, MBD1-containing chromatin associated factor 2
, MBD1-containing chromatin-associated factor 2
, activating transcription factor 7-interacting protein 2
, protein similar to MCAF2