ATF7IP2 Antikörper (N-Term)
Kurzübersicht für ATF7IP2 Antikörper (N-Term) (ABIN2790606)
Target
Alle ATF7IP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Verwendungszweck
- ATF7IP2 Antibody - N-terminal region
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Sequenz
- EEIVHSETKL EQVVCSYQKP SRTTESPSRV FTEEAKDSLN TSENDSEHQT
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Homologie
- Human: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ATF7IP2. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human ATF7IP2
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP67011-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))
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Andere Bezeichnung
- ATF7IP2
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Hintergrund
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Background Information: ATF7IP2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. It can both act as an activator or a repressor depending on the context. ATF7IP2 mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity.
Alternative Symbols: MCAF2
Protein Name: Activating transcription factor 7-interacting protein 2
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Molekulargewicht
- 59kDa
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Gen-ID
- 80063
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NCBI Accession
- NP_001243089
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UniProt
- Q5U623
Target
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