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The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Zusätzlich bieten wir Ihnen ATPase, Class I, Type 8A, Member 1 Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.
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Knockdown of ATP8A1 (a recycling endosome phosphatidlyserine-flippase) suppresses nuclear localization of YAP (zeige YAP1 Antikörper) and YAP (zeige YAP1 Antikörper)-dependent transcription. ATP8A1 knockdown increases the phosphorylated (activated) form of Lats1 that phosphorylates and inactivates YAP (zeige YAP1 Antikörper).
The increased level of intracellular ATP8A1 protein attenuated the inhibitor role of miR (zeige MLXIP Antikörper)-140-3p in the growth and mobility of NSCLC cell.
Depletion of ATP8A1 impaired the asymmetric transbilayer distribution of phosphatidylserine in recycling endosomes, dissociated EHD1 (zeige EHD1 Antikörper) from recycling endosomes, and generated aberrant endosomal tubules that appear resistant to fission.
the phospholipid flippase complex of ATP8A1 and CDC50A proteins has a role in cell migration
APLT has a role in macrophage-induced nitrosylation/oxidation plays an important role in cell clearance
The data of this study strongly indicated that Atp8a1 plays a central role in the PM-APLT activity of some mammalian cells.
role in normal phospholipid distribution in the bilayer, and for normal binding, penetration, and signaling by the zona pellucida
ATPase (zeige DNAH8 Antikörper) activity of the secretory granule Atp8a1 is activated by phospholipids binding to a specific site
Such observations suggest tissue-specific differences in transcription initiation complex assembly and regulation of ATPase II gene expression.
The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes. Several subfamilies of P-type ATPases have been identified. One subfamily catalyzes transport of heavy metal ions. Another subfamily transports non-heavy metal ions (NMHI). The protein encoded by this gene is a member of the third subfamily of P-type ATPases and acts to transport amphipaths, such as phosphatidylserine. Two transcript variants encoding different isoforms have been found for this gene.
probable phospholipid-transporting ATPase IA
, ATPase II
, ATPase class I type 8A member 1
, aminophospholipid translocase
, chromaffin granule ATPase II
, ATPase 8A1, aminophospholipid transporter (APLT), class I
, ATPase 8A1, p type