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ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking.
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Human Polyclonal ARFGEF2 Primary Antibody für ICC, IF - ABIN4281377
Christis, Munro: The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2. in The Journal of cell biology 2012
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition.
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
, cytohesin 1-like
, brefeldin A-inhibited GEP 2
, brefeldin A-inhibited guanine nucleotide-exchange protein 2
, Brefeldin A-inhibited guanine nucleotide-exchange factor 2