ARFGEF2 Antikörper
(ADP-Ribosylation Factor Guanine Nucleotide-Exchange Factor 2 (Brefeldin A-Inhibited) (ARFGEF2))
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008].
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Ausgewählte ARFGEF2 Kategorien
ARFGEF2 Antikörper
High quality antibodies with extensive validation data.
Empfohlene ARFGEF2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7145776
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN6258592
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (1)
Kat. Nr.
ABIN7184628
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ARFGEF2 Produkten
: "Arf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 34, pp. E3162-70, (2013) (PubMed).: "The small G protein Arl1 directs the trans-Golgi-specific targeting of the Arf1 exchange factors BIG1 and BIG2." in: The Journal of cell biology, Vol. 196, Issue 3, pp. 327-35, (2012) (PubMed).
: "cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2." in: The Journal of biological chemistry, Vol. 283, Issue 37, pp. 25364-71, (2008) (PubMed).
Synonyme und alternative Namen zu ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2), ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (Arfgef2), ADP ribosylation factor guanine nucleotide exchange factor 2 (Arfgef2), AI463430, AW493672, BIG2, Big2, dJ1164I10.1, E230011G24Rik, PVNH2Bezeichner auf Proteinebene für ARFGEF2
- ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
- cytohesin 1-like
- brefeldin A-inhibited GEP 2
- brefeldin A-inhibited guanine nucleotide-exchange protein 2
- Brefeldin A-inhibited guanine nucleotide-exchange factor 2
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