anti-TCF3 (TCF3) Antikörper

Auf finden Sie aktuell 181 Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TCF3 Kits (7) und TCF3 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 207 TCF3 Produkte verfügbar.
A1, AA408400, ALF2, AW209082, bhlhb21, e2a, E12, E12/E47, E47, G12, itf1, ME2, Pan1, Pan2, TCF-3, Tcf3, tcf3a, TCF7L1, tcfe2a, vdir, xtcf-3, xtcf3, zgc:113045
Alle Antikörper anzeigen Gen GeneID UniProt
TCF3 83439 Q9HCS4
TCF3 21423 P15806
TCF3 312451  

Meistgesuchte Reaktivitäten zu anti-TCF3 (TCF3) Antikörper

anti-Human TCF3 Antikörper:

anti-Mouse (Murine) TCF3 Antikörper:

anti-Rat (Rattus) TCF3 Antikörper:

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Weitere Antikörper gegen TCF3 Interaktionspartner

Human Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Interaktionspartner

  1. Poly (ADP-ribose) polymerase (zeige PARP1 Antikörper) inhibitors selectively induce cytotoxicity in TCF3-HLF (zeige EPAS1 Antikörper)-positive leukemic cells.

  2. MiR (zeige MLXIP Antikörper)-138 may be a tumor suppressor and potential prognostic biomarker in cervical cancer. Its downstream target, TCF3, may also regulate cancer development in a reverse manner as miR (zeige MLXIP Antikörper)-138.

  3. High levels of TCF3 in gliomas promote glioma development through the Akt (zeige AKT1 Antikörper) and Erk (zeige EPHB2 Antikörper) pathways.

  4. TWIST1 (zeige TWIST1 Antikörper)-E12 (zeige ELSPBP1 Antikörper) protein heterodimeric complexes may thus constitute the main active forms of TWIST1 (zeige TWIST1 Antikörper) with regard to senescence inhibition over the time course of breast tumorigenesis.

  5. Review of the role of the E2A-PBX1 (zeige PBX1 Antikörper) gene rearrangement in the prognosis of childhood acute lymphoblastic leukemia and its central nervous system relapse.

  6. Our data suggest that E2A antagonism of PU.1 activity contributes to its ability to commit multipotential hematopoietic progenitors to the lymphoid lineages.

  7. E47 is a novel substrate of PAK5 (zeige PAK6 Antikörper), and PAK5 (zeige PAK6 Antikörper)-mediated phosphorylation of E47 promotes epithelial-mesenchymal transition. High expression of phospho-E47 was associated with an aggressive phenotype of colon cancer and metastasis.

  8. We observed significant enrichment of the neuroactive ligand-receptor interaction pathway in TCF3-PBX1 (zeige PBX1 Antikörper) as well as an enrichment of genes involved in immunity and infection pathways in ETV6 (zeige ETV6 Antikörper)-RUNX1 (zeige RUNX1 Antikörper) subtype

  9. Over expression of E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential.

  10. Drug response profiling of matched patient-derived xenografts revealed a distinct profile for TCF3-HLF (zeige EPAS1 Antikörper) ALL with resistance to conventional chemotherapeutics but sensitivity to glucocorticoids.

Mouse (Murine) Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Interaktionspartner

  1. If Gfi1 (zeige ZNF163 Antikörper) levels fall below a threshold, Id1 (zeige ID1 Antikörper) expression increases and renders E2A unable to function, which prevents hematopoietic progenitors from engaging along the B lymphoid lineage

  2. these data identified E2A and E2-2 (zeige TCF4 Antikörper) as central regulators of B cell immunity.

  3. down-regulation of Id3 (zeige ID3 Antikörper) in B cells is essential for releasing E2A and E2-2 (zeige TCF4 Antikörper), which in a redundant manner are required for antigen-induced B cell differentiation.

  4. Data suggest a novel mechanism of drug resistance in which E2a and PRC2 drive changes in the B-cell epigenome; these alterations attenuate alkylating agent treatment-induced apoptosis.

  5. These findings suggest that miR (zeige MLXIP Antikörper)-506-3p played an important role in regulating NSC proliferation and differentiation via targeting TCF3 (zeige TCF7L1 Antikörper), and provide a promising avenue for future in-depth research into the functions of miR (zeige MLXIP Antikörper)-506-3p and TCF3 (zeige TCF7L1 Antikörper) in nervous system development.

  6. Conditional expression of E2A-HLF (zeige HLF Antikörper) induces B-cell precursor death and myeloproliferative-like disease in knock-in mice.

  7. Upregulation of E12/E47 by HBx ultimately and concomitant repression of E-cadherin (zeige CDH1 Antikörper) expression led to epithelial-mesenchymal transition in human hepatocytes.

  8. Mechanistically, E47 repressed the expression of several astrocyte-specific genes in adult NSPCs.

  9. Tcf3 (zeige TCF7L1 Antikörper) is upregulated in skin wounds and Tcf3 (zeige TCF7L1 Antikörper) overexpression accelerates keratinocyte migration and skin wound healing.

  10. Loss and gain of function analyses combined with in vivo studies in syngeneic breast cancer models demonstrate the participation of LOXL2 (zeige LOXL3 Antikörper) and E47 in tumor growth and their requirement for lung metastasis.

Xenopus laevis Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3) Interaktionspartner

  1. Data indicte that Tcf-1 (zeige HNF1A Antikörper) and Lef-1 (zeige LEF1 Antikörper) exhibit a function in the axis induction assay, which is lacking in Tcf-3 and -4.

TCF3 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1\;19), with PBX1), childhood leukemia (t(19\;19), with TFPT) and acute leukemia (t(12\;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Alternative names and synonyms associated with TCF3

  • transcription factor 7-like 1 (T-cell specific, HMG-box) (TCF7L1) Antikörper
  • transcription factor 3 (TCF3) Antikörper
  • transcription factor 3b (tcf3b) Antikörper
  • transcription factor 3 (Tcf3) Antikörper
  • transcription factor 7-like 1 (T-cell specific, HMG-box) (Tcf7l1) Antikörper
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (tcf3) Antikörper
  • transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) (TCF3) Antikörper
  • A1 Antikörper
  • AA408400 Antikörper
  • ALF2 Antikörper
  • AW209082 Antikörper
  • bhlhb21 Antikörper
  • e2a Antikörper
  • E12 Antikörper
  • E12/E47 Antikörper
  • E47 Antikörper
  • G12 Antikörper
  • itf1 Antikörper
  • ME2 Antikörper
  • Pan1 Antikörper
  • Pan2 Antikörper
  • TCF-3 Antikörper
  • Tcf3 Antikörper
  • tcf3a Antikörper
  • TCF7L1 Antikörper
  • tcfe2a Antikörper
  • vdir Antikörper
  • xtcf-3 Antikörper
  • xtcf3 Antikörper
  • zgc:113045 Antikörper

Bezeichner auf Proteinebene für TCF3

HMG box transcription factor 3 , transcription factor 7-like 1 , VDR interacting repressor , class B basic helix-loop-helix protein 21 , helix-loop-helix protein HE47 , immunoglobulin transcription factor 1 , kappa-E2-binding factor , negative vitamin D response element-binding protein , transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) , transcription factor E2-alpha , transcription factor ITF-1 , vitamin D receptor-interacting repressor , transcription factor 3 , TCF-3 , immunoglobulin enhancer-binding factor E12/E47 , transcription factor A1 , transcription factor E2a , pancreas specific transcription factor 1c , transcription regulator Pan , transcription factor XE12/XE47 , class A basic helix-loop-helix transcription factor G12 , helix-loop-helix protein E12 , helix-loop-helix protein E47 , transcription factor 7-like 1 (T-cell specific, HMG-box)

83439 Homo sapiens
6929 Homo sapiens
664768 Danio rerio
21423 Mus musculus
312451 Rattus norvegicus
171046 Rattus norvegicus
379355 Xenopus laevis
395146 Gallus gallus
485079 Canis lupus familiaris
530616 Bos taurus
Ausgewählte Anbieter für anti-TCF3 (TCF3) Antikörper
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