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anti-TICAM1 (TICAM1) Antikörper

anti-Toll-Like Receptor Adaptor Molecule 1 Antikörper (TICAM1)
Auf finden Sie aktuell 80 Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TICAM1 Kits (7) und TICAM1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 98 TICAM1 Produkte verfügbar.
AW046014, AW547018, IIAE6, MyD88-3, PRVTIRB, TICAM-1, trif
Alle Antikörper anzeigen Gen GeneID UniProt
TICAM1 148022 Q8IUC6
TICAM1 106759 Q80UF7
TICAM1 363328  

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Meistgesuchte Reaktivitäten zu anti-TICAM1 (TICAM1) Antikörper

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anti-Human TICAM1 Antikörper:

anti-Mouse (Murine) TICAM1 Antikörper:

anti-Rat (Rattus) TICAM1 Antikörper:

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Am meisten referenzierte anti-TICAM1 Antikörper

  1. Human Polyclonal TICAM1 Primary Antibody für ICC, IF - ABIN266066 : Hoebe, Du, Georgel, Janssen, Tabeta, Kim, Goode, Lin, Mann, Mudd, Crozat, Sovath, Han, Beutler: Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. in Nature 2003 (PubMed)
    Zeige alle 23 Referenzen für ABIN266066

  2. Human Polyclonal TICAM1 Primary Antibody für WB - ABIN1881885 : Bin, Xu, Shu: TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 5 Referenzen für ABIN1881885

  3. Human Polyclonal TICAM1 Primary Antibody für EIA, IHC (p) - ABIN501042 : ONeill, Fitzgerald, Bowie: The Toll-IL-1 receptor adaptor family grows to five members. in Trends in immunology 2003 (PubMed)
    Zeige alle 4 Referenzen für ABIN501042

  4. Human Polyclonal TICAM1 Primary Antibody für IP, WB - ABIN1169062 : Carty, Goodbody, Schröder, Stack, Moynagh, Bowie: The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. in Nature immunology 2006 (PubMed)
    Zeige alle 3 Referenzen für ABIN1169062

  5. Human Polyclonal TICAM1 Primary Antibody für DB, EIA - ABIN493536 : Fitzgerald, Golenbock: Immunology. The shape of things to come. in Science (New York, N.Y.) 2007 (PubMed)
    Zeige alle 3 Referenzen für ABIN493536

  6. Human Polyclonal TICAM1 Primary Antibody für ELISA, ICC - ABIN4362350 : Shi, Kehrl: MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen TICAM1 Interaktionspartner

Human Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Interaktionspartner

  1. The NF-kappaB (zeige NFKB1 Antikörper) activated by dsRNA appears not to be the canonical p65 (zeige GORASP1 Antikörper)/p50 (zeige CD40 Antikörper) heterodimers.

  2. We confirmed associations with papillary thyroid cancer and SNPs in FOXE1 (zeige FOXE1 Antikörper)/HEMGN, SERPINA5 (zeige SERPINA5 Antikörper) (rs2069974), FTO (zeige FTO Antikörper) (rs8047395), EVPL (zeige EVPL Antikörper) (rs2071194), TICAM1 (rs8120) and SCARB1 (zeige SCARB1 Antikörper) (rs11057820) genes. We found associations with SNPs in FOXE1 (zeige FOXE1 Antikörper), SERPINA5 (zeige SERPINA5 Antikörper), FTO (zeige FTO Antikörper), TICAM1 and HSPA6 (zeige HSPA6 Antikörper) and and follicular thyroid cancer

  3. IL-12p70 production requires uptake of Streptococcus pneumoniae as well as the presence of the adaptor molecule TRIF (zeige TRIM69 Antikörper).

  4. TIRF high-content imaging system simultaneously showed the expression pattern of EGFRs and EC50 value for CPT (zeige CHPT1 Antikörper)-induced apoptosis and necrosis in MCF-7, SK-BR-3 and JIMT-1 cancer cell line

  5. involved in signaling that moderates the expression of heme oxygenase1 and il-8 (zeige IL8 Antikörper) after keratinocytes exposure to dinitrochlorobenzene

  6. Using bone marrow derived macrophages from knockout mice we demonstrate that hBD3 (zeige DEFB103A Antikörper) suppresses the polyI:C-induced TLR3 (zeige TLR3 Antikörper) response mediated by TICAM1 (TRIF), while exacerbating the cytoplasmic response through MDA5 (IFIH1 (zeige IFIH1 Antikörper)) and MAVS (IPS1/CARDIF (zeige MAVS Antikörper)).

  7. signaling through TRIF (zeige TRIM69 Antikörper) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  8. Data show that toll-like receptor 3 (zeige TLR3 Antikörper)/TRIF (zeige TRIM69 Antikörper) protein signalling regulates cytokines IL-32 (zeige IL32 Antikörper) and IFN-beta (zeige IFNB1 Antikörper) secretion by activation of receptor-interacting protein-1 (RIP-1 (zeige RIPK1 Antikörper)) and tumour necrosis factor (zeige TNF Antikörper) receptor-associated factor 6 (TRAF6 (zeige TRAF6 Antikörper)) in cornea epithelial cells.

  9. WDFY1 (zeige WDFY1 Antikörper) mediates TLR3 (zeige TLR3 Antikörper)/TLR4 (zeige TLR4 Antikörper) signaling by recruiting TRIF (zeige TRIM69 Antikörper).

  10. In mic (zeige AGT Antikörper)e with nonfunctional TRIF (Trif(mut) mice), Ang II-induced hypertension and cardiac hypertrophy were abrogated, and proinflammatory gene expression in heart and kid (zeige TRIM69 Antikörper)neys was unchanged or decreased. These results indicate that Ang II induces activation of a proinflammatory innate immune response, causing hypertension and cardiac hypertrophy, which require functional adaptor protein TRIF-mediated pathways.

Mouse (Murine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Interaktionspartner

  1. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (zeige FOSL1 Antikörper) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (zeige TRAF3 Antikörper)), TIR domain-containing adapter inducing IFN-beta (zeige IFNB1 Antikörper) (TRIF (zeige RNF138 Antikörper)), and Tank-binding kinase 1 (TBK1 (zeige TBK1 Antikörper)) via impairing K63-linked polyubiquitination of TRAF3 (zeige TRAF3 Antikörper) and TRIF (zeige RNF138 Antikörper).

  2. These results suggested the importance of TRIF (zeige RNF138 Antikörper) in TLR2 (zeige TLR2 Antikörper) mediated foam cell formation via inflammatory mediators, including MCP-1 (zeige CPT1B Antikörper).

  3. DENV replication and IFNalpha/beta, TNF-alpha (zeige TNF Antikörper), IL-12 (zeige IL12A Antikörper) and IL-18 (zeige IL18 Antikörper) in infected cultures at 24h were found. All of these parameters were significantly decreased after TRIF (zeige RNF138 Antikörper), MYD88 (zeige MYD88 Antikörper) or NF-kB inhibition

  4. The authors demonstrate that, in addition to MyD88 (zeige MYD88 Antikörper), Yersinia pseudotuberculosis inhibits TRIF (zeige RNF138 Antikörper) signaling through the type III secretion system effector YopJ.

  5. Results show that toll (zeige TLR4 Antikörper)/IL-1 (zeige IL1A Antikörper) domain-containing adaptor inducing IFN-beta (zeige IFNB1 Antikörper) (TRIF (zeige RNF138 Antikörper)) is essential for Toll (zeige TLR4 Antikörper)-like receptors TLR3 (zeige TLR3 Antikörper)- and TLR4 (zeige TLR4 Antikörper)-mediated innate immune responses in peritoneal mesothelial cells (PMCs).

  6. Data show that annexin A2 (AnxA2 (zeige ANXA2 Antikörper)) directly exerted negative regulation of inflammatory responses through Toll-like receptor 4 (TLR4 (zeige TLR4 Antikörper))-initiated TRAM protein (zeige TRAM2 Antikörper)-TRIF (zeige RNF138 Antikörper) protein pathway occurring on endosomes.

  7. ProTalpha preconditioning-induced prevention of retinal ischemic damage is mediated by selective activation of the TIR-domain-containing adapter-inducing interferon-beta (zeige IFNB1 Antikörper) interferon regulatory factor 3 (zeige IRF3 Antikörper) pathway downstream of toll-like receptor 4 (zeige TLR4 Antikörper) in microglia

  8. signaling through TRIF (zeige RNF138 Antikörper) is important for the inflammatory response of AngII-induced abdominal aortic aneurysm formation

  9. analysis of how MyD88 (zeige MYD88 Antikörper) and TRIF (zeige RNF138 Antikörper) affect TLR4 (zeige TLR4 Antikörper) activation

  10. Ang II (zeige AGT Antikörper) induces activation of a proinflammatory innate immune response, causing hypertension and cardiac hypertrophy. These effects require functional adaptor protein TRIF (zeige RNF138 Antikörper)-mediated pathways.

Cow (Bovine) Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Interaktionspartner

  1. Inhibition of the Toll (zeige TLR4 Antikörper)/interleukin-1 receptor (TIR) domain-containing adapter-inducing interferon-beta (zeige IFNB1 Antikörper) signaling reduced permeability changes and apoptosis in endothelial cells exposed to lipopolysaccharide.

Zebrafish Toll-Like Receptor Adaptor Molecule 1 (TICAM1) Interaktionspartner

  1. 3D-models of rohu TLR3 (zeige TLR3 Antikörper)-TIR and zebrafish TRIF

  2. The role of zebrafish (Danio rerio) TICAM1 in activating NF-kappaB (zeige NFKB1 Antikörper) and zebrafish type I IFN was described.

  3. study focuses on the functional characterization of zebrafish TRIF; results show that the full length cDNA of zebrafish TRIF encodes a protein of 556 amino acids; TRIF is able to induce the IFN promoter as well as activate NF-kappaB (zeige NFKB1 Antikörper) response promoter

TICAM1 Antigen-Profil

Beschreibung des Gens

This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response.

Alternative names and synonyms associated with TICAM1

  • toll-like receptor adaptor molecule 1 (TICAM1) Antikörper
  • toll-like receptor adaptor molecule 1 (LOC100231928) Antikörper
  • toll-like receptor adaptor molecule 1 (Ticam1) Antikörper
  • toll-like receptor adaptor molecule 1 (ticam1) Antikörper
  • AW046014 Antikörper
  • AW547018 Antikörper
  • IIAE6 Antikörper
  • MyD88-3 Antikörper
  • PRVTIRB Antikörper
  • TICAM-1 Antikörper
  • trif Antikörper

Bezeichner auf Proteinebene für TICAM1

TIR domain-containing adapter molecule 1 , TIR domain containing adaptor inducing interferon-beta , toll-interleukin I receptor domain containing adaptor molecule 1 , toll-like receptor adaptor molecule 1 , TIR domain-containing adapter molecule 1-like , TIR domain-containing adapter protein inducing IFN-beta , proline-rich, vinculin and TIR domain-containing protein B , putative NF-kappa-B-activating protein 502H , toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta , TIR domain-containing adaptor inducing interferon-beta , toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta , TICAM-1 , TIR-domain containing adaptor inducing IFN-beta , TRIF/TICAM1

468677 Pan troglodytes
574294 Macaca mulatta
611852 Canis lupus familiaris
100062414 Equus caballus
100231928 Taeniopygia guttata
100405343 Callithrix jacchus
100588929 Nomascus leucogenys
148022 Homo sapiens
106759 Mus musculus
510427 Bos taurus
363328 Rattus norvegicus
403147 Danio rerio
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