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MAPK11 Antikörper

MAPK11 Reaktivität: Human, Maus IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN966523
  • Target Alle MAPK11 Antikörper anzeigen
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Reaktivität
    • 66
    • 33
    • 22
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 81
    • 4
    • 3
    Kaninchen
    Klonalität
    • 83
    • 5
    Polyklonal
    Konjugat
    • 38
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MAPK11 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 44
    • 29
    • 26
    • 26
    • 11
    • 7
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of human MAPK11 (Mitogen-activated protein kinase 11)
    Top Product
    Discover our top product MAPK11 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C
  • Kumar, McDonnell, Gum, Hand, Lee, Young: "Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 533-8, (1997) (PubMed).

    Stein, Yang, Young, Janknecht, Hunter, Murray, Barbosa: "p38-2, a novel mitogen-activated protein kinase with distinct properties." in: The Journal of biological chemistry, Vol. 272, Issue 31, pp. 19509-17, (1997) (PubMed).

    Jiang, Chen, Li, Guo, Gegner, Lin, Han: "Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)." in: The Journal of biological chemistry, Vol. 271, Issue 30, pp. 17920-6, (1996) (PubMed).

  • Target
    MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))
    Andere Bezeichnung
    MAPK11 (MAPK11 Produkte)
    Synonyme
    ATMPK11 antikoerper, F22L4.10 antikoerper, F22L4_10 antikoerper, MAP kinase 11 antikoerper, zgc:86905 antikoerper, P38B antikoerper, P38BETA2 antikoerper, PRKM11 antikoerper, SAPK2 antikoerper, SAPK2B antikoerper, p38-2 antikoerper, p38Beta antikoerper, P38b antikoerper, Prkm11 antikoerper, Sapk2 antikoerper, Sapk2b antikoerper, p38beta antikoerper, p38beta2 antikoerper, p38b antikoerper, sapk2 antikoerper, prkm11 antikoerper, sapk2b antikoerper, mitogen-activated protein kinase 11 antikoerper, MAP kinase 11 antikoerper, mapk11 antikoerper, LOC9328118 antikoerper, MPK11 antikoerper, MAPK11 antikoerper, Mapk11 antikoerper, PTRG_02565 antikoerper
    Hintergrund
    MAPK11 (Mitogen-activated protein kinase 11) is involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. MAPK11 (Mitogen-activated protein kinase 11) phosphorylates preferentially transcription factor ATF2. MAPK11 (Mitogen-activated protein kinase 11) is activated by phosphorylation on threonine and tyrosine by MKK6. MAPK11 is inhibited by pyridinyl-imidazole related compounds. Highest levels of MAPK11 expression is in the brain and heart. MAPK11 is also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas. The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. MAPK11 is dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme. MAPK11 belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family and MAP kinase subfamily. MAPK11 contains 1 protein kinase domain.
    Synonyms: PRKM11, SAPK2 (Stress-activated protein kinase 2), p38-2 (Mitogen-activated protein kinase p38 beta), p38b (MAP kinase p38 beta)
    Pathways
    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine
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