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BCL10 Antikörper
BCL10
Reaktivität: Human
WB, IHC, ELISA
Monoclonal
unconjugated
Produktdetails anti-BCL10 Antikörper
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Target
Alle BCL10 Antikörper anzeigen
BCL10
(B-Cell CLL/lymphoma 10 (BCL10))
Reaktivität
Alle Reaktivitäten für BCL10 Antikörper
Human
Wirt
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Klonalität
Alle Klonalitäten für BCL10 Antikörper
Monoklonal
Konjugat
Alle Konjugate für BCL10 Antikörper
Dieser BCL10 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BCL10 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Spezifität
Ni-NTA purified recombinant human BCL-10 expressed in E. Coli strain BL21 (DE3).
Aufreinigung
Antibodies are purified by protein A affinity chromatography
Isotyp
IgG1
Top Product
Discover our top product BCL10 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
IHC(P): Dilution 1: 100- 1: 500 IHC(F): Dilution 1: 200- 1: 1000 Western blot: Dilution 1: 2000- 1: 5000 ELISA: Propose dilution 1: 10000. Determining optimal working dilutions by titration test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Lagerung
-20 °C
Referenzen für anti-BCL10 Antikörper (ABIN965650)
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Cahill : "Vasoconstrictor responsiveness of portal hypertensive vessels. " in: Clinical science (London, England : 1979) , Vol. 96 , Issue 1 , pp. 3-4 , (1999 ) (PubMed ).
Details zu BCL10
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Target
BCL10
(B-Cell CLL/lymphoma 10 (BCL10))
Andere Bezeichnung
BCL-10 (BCL10 Produkte )
Synonyme
CARMEN antikoerper, CIPER antikoerper, CLAP antikoerper, c-E10 antikoerper, mE10 antikoerper, BCL10 antikoerper, AI132454 antikoerper, BCL-10 antikoerper, C81403 antikoerper, ME10 antikoerper, cE10 antikoerper, bcl10 antikoerper, B-cell CLL/lymphoma 10 antikoerper, B-cell lymphoma/leukemia 10-like antikoerper, B cell leukemia/lymphoma 10 antikoerper, B-cell lymphoma/leukemia 10 antikoerper, BCL10 antikoerper, Bcl10 antikoerper, bcl10 antikoerper, LOC100223183 antikoerper
Hintergrund
Bcl-10 is a 31kDa protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.
Gen-ID
8915
Pathways
T-Zell Rezeptor Signalweg , Fc-epsilon Rezeptor Signalübertragung , Activation of Innate immune Response , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Tube Formation , Positive Regulation of Endopeptidase Activity , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteine
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