»
Antikörper
»
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1...
X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1) Antikörper (Cy5)
| Antigen |
|
| Synonyme |
RCC, Xrcc-1, MGC102556, xrcc1, MGC80909, XRCC1 |
| Klonalität |
Polyklonal |
|
Wirt
|
|
|
Reaktivität
|
|
|
Konjugat
|
Biotin (4), Agarose Beads (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Applikation
|
 Alternativen Durchflusszytometrie (FACS), Immunfluoreszenz (IF)
Western Blot (WB) (57), Immunpräzipitation (IP) (36), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Immunfluoreszenz (IF) (31), Durchflusszytometrie (FACS) (19), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), ELISA (6), Immunhistochemie (IHC) (5), Enzyme Immunoassay (EIA) (4), ELISA (Detektionsantikörper) (3), Immunzytochemie (ICC) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
|
| Produktnummer |
ABIN673543 |
| Menge |
100 µg (1mg/1ml) |
| Preis |
290,60 € Zzgl. Versandkosten €20,00 und MWSt
|
| Lieferung nach |
|
| Verfügbarkeit |
Lieferung in 10 bis 15 Werktagen |
|
Weitere Bezeichnung
|
XRCC1
|
|
Immunogen
|
Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human XRCC1 C-terminus
|
|
Format
|
Lyophilized
|
|
Wiederherstellung
|
Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
|
|
Isotyp
|
IgG
|
|
Beschreibung
|
Synonym: DNA repair protein XRCC1, RCC, X ray repair complementing defective repair in chinese hamster, X ray repair complementing defective repair in chinese hamster cells 1, X ray Repair Complementing Defective Repair in Chinese Hamster Cells, X ray repair cross complementing protein 1, XRCC 1.
|
|
Spezifität
|
Excitation / Emission Wavelengths: 650nm/670nm
|
|
Molekulargewicht
|
70-85kDa
|
|
Kommentare
|
XRCC1 is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. In testis XRCC1 is expressed at high levels.
|
|
Applikationshinweise
|
Flow-Cyt (1:50-200), IF (1:50-200)
|
|
Konzentration
|
1mg/1ml
|
|
Reinigung
|
Antibodies are purified by protein A and peptide affinity chromatography.
|
|
Buffer
|
0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
|
|
Lagerung
|
Ship at room temperature. Store at -20°C
|
|
Forschungsgebiet
|
Krebs, DNS/RNS
|
|
Beschränkungen
|
Nur für Forschungszwecke einsetzbar
|
Alternativen zu Antigen "X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 1 (XRCC1)", Typ "Antikörper" finden
|
Wirte
|
Kaninchen (43), Maus (37)
|
|
Reaktivitäten
|
Human (80), Ratte (Rattus) (32), Maus (24), Hamster (3), Pferd (3), Kaninchen (3), Rind (Kuh) (2), Hund (2), Schwein (2)
|
|
Applikationen
|
Western Blot (WB) (57), Immunpräzipitation (IP) (36), Immunhistochemie (Paraffinschnitte) (IHC (p)) (32), Immunfluoreszenz (IF) (31), Durchflusszytometrie (FACS) (19), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (8), ELISA (6), Immunhistochemie (IHC) (5), Enzyme Immunoassay (EIA) (4), ELISA (Detektionsantikörper) (3), Immunzytochemie (ICC) (3), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
|
|
Konjugate
|
Biotin (4), Agarose Beads (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
|
|
Epitope
|
pSer461 (1), pSer485/pThr488 (1), pSer518/pThr519/523 (1)
|
